Q84W27

PR
Gene name
SCPL43 (At2g12480, T27D6.5)
Protein name
Serine carboxypeptidase-like 43
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G12480
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

398-442 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q84W27

Entry ID Method Resolution Chain Position Source
AF-Q84W27-F1 Predicted AlphaFoldDB

95 variants for Q84W27

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00222934 4 S>C No 1000Genomes
tmp_2_5072201_C_A 9 M>I No 1000Genomes
ENSVATH01747142 9 M>V No 1000Genomes
ENSVATH12914212 11 I>V No 1000Genomes
tmp_2_5072194_T_C 12 M>V No 1000Genomes
ENSVATH05404997 13 V>G No 1000Genomes
ENSVATH05404998 13 V>I No 1000Genomes
tmp_2_5072184_A_G 15 V>A No 1000Genomes
ENSVATH01747140 16 T>S No 1000Genomes
tmp_2_5072161_C_T 23 A>T No 1000Genomes
tmp_2_5072156_T_A 24 E>D No 1000Genomes
tmp_2_5072157_T_C 24 E>G No 1000Genomes
ENSVATH14336337 26 Y>F No 1000Genomes
ENSVATH14336337 26 Y>S No 1000Genomes
ENSVATH05404994 30 D>E No 1000Genomes
ENSVATH05404995 30 D>N No 1000Genomes
ENSVATH00222932 38 Q>E No 1000Genomes
ENSVATH01747138 46 F>Y No 1000Genomes
ENSVATH05404993 53 D>N No 1000Genomes
ENSVATH00222930 55 E>A No 1000Genomes
ENSVATH05404990 66 E>K No 1000Genomes
ENSVATH05404989 67 A>S No 1000Genomes
ENSVATH00222929 70 E>Q No 1000Genomes
ENSVATH01747132 93 A>S No 1000Genomes
ENSVATH12914165 93 A>V No 1000Genomes
ENSVATH05404984 103 T>M No 1000Genomes
ENSVATH01747126 126 E>D No 1000Genomes
ENSVATH01747125 127 S>L No 1000Genomes
ENSVATH05404978 140 S>A No 1000Genomes
ENSVATH01747124 148 S>T No 1000Genomes
tmp_2_5071528_T_C 151 N>S No 1000Genomes
ENSVATH12914092 153 M>I No 1000Genomes
ENSVATH12914090 166 E>G No 1000Genomes
tmp_2_5071484_C_T 166 E>K No 1000Genomes
ENSVATH12914089 169 S>A No 1000Genomes
tmp_2_5071469_C_T 171 D>N No 1000Genomes
ENSVATH00222925 173 F>C No 1000Genomes
tmp_2_5071301_G_C 182 H>D No 1000Genomes
ENSVATH12914088 184 I>L No 1000Genomes
tmp_2_5071291_G_A 185 P>L No 1000Genomes
ENSVATH05404962 188 A>V No 1000Genomes
ENSVATH01747117 189 D>N No 1000Genomes
ENSVATH12914087 196 S>P No 1000Genomes
ENSVATH01747116 197 R>C No 1000Genomes
ENSVATH05404960 199 S>R No 1000Genomes
tmp_2_5070877_G_A 213 P>S No 1000Genomes
ENSVATH05404949 218 D>H No 1000Genomes
ENSVATH14336113 219 R>K No 1000Genomes
ENSVATH12914002 230 S>* No 1000Genomes
ENSVATH01747106 241 T>R No 1000Genomes
tmp_2_5070790_T_C 242 I>V No 1000Genomes
tmp_2_5070762_G_A 251 P>L No 1000Genomes
ENSVATH05404947 252 K>E No 1000Genomes
ENSVATH00222924 262 I>V No 1000Genomes
ENSVATH05404945 274 S>N No 1000Genomes
tmp_2_5070685_T_C 277 I>V No 1000Genomes
tmp_2_5070654_A_G 287 V>A No 1000Genomes
ENSVATH01747105 289 Q>E No 1000Genomes
tmp_2_5070475_C_T 298 A>T No 1000Genomes
ENSVATH05404942 298 A>V No 1000Genomes
ENSVATH05404941 304 T>N No 1000Genomes
ENSVATH05404941 304 T>S No 1000Genomes
ENSVATH00222922 305 R>C No 1000Genomes
ENSVATH00222921 305 R>H No 1000Genomes
ENSVATH00222920 313 C>S No 1000Genomes
ENSVATH05404937 316 R>Q No 1000Genomes
ENSVATH00222918 316 R>W No 1000Genomes
tmp_2_5070317_T_C 320 S>G No 1000Genomes
tmp_2_5070316_C_A 320 S>I No 1000Genomes
ENSVATH01747102 322 I>L No 1000Genomes
ENSVATH12914000 326 I>N No 1000Genomes
ENSVATH05404936 339 Q>* No 1000Genomes
tmp_2_5070253_G_A 341 P>L No 1000Genomes
ENSVATH05404931 351 S>F No 1000Genomes
tmp_2_5070148_T_C 353 I>V No 1000Genomes
ENSVATH05404930 363 R>Q No 1000Genomes
ENSVATH14336112 368 D>H No 1000Genomes
ENSVATH01747100 371 F>Y No 1000Genomes
ENSVATH00222916 375 I>V No 1000Genomes
ENSVATH05404929 379 A>G No 1000Genomes
tmp_2_5069965_C_A 387 G>C No 1000Genomes
tmp_2_5069952_G_A 391 T>I No 1000Genomes
ENSVATH00222912 396 L>Q No 1000Genomes
ENSVATH05404927 413 E>K No 1000Genomes
tmp_2_5069886_T_A 413 E>V No 1000Genomes
tmp_2_5069884_GC_AC,G 414 P>S No 1000Genomes
tmp_2_5069849_C_A 425 M>I No 1000Genomes
ENSVATH00222911 425 M>L No 1000Genomes
ENSVATH00222911 425 M>V No 1000Genomes
tmp_2_5069834_C_A 430 L>F No 1000Genomes
ENSVATH12913996 433 K>R No 1000Genomes
ENSVATH05404925 434 P>L No 1000Genomes
ENSVATH12913995 436 L>* No 1000Genomes
tmp_2_5069813_C_A 437 K>N No 1000Genomes
tmp_2_5069800_C_T 442 D>N No 1000Genomes

No associated diseases with Q84W27

1 regional properties for Q84W27

Type Name Position InterPro Accession
active_site Serine carboxypeptidase, serine active site 174 - 181 IPR018202

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

1 GO annotations of molecular function

Name Definition
serine-type carboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9MAR8 SCPL44 Serine carboxypeptidase-like 44 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVSSRAVVMA IMVLVTVQWL VFAEGYPEED LVARLPGQPN VGFRQFAGYV DVDSENGRSL
70 80 90 100 110 120
FYYYVEAVKE PDTKPLTLWL NGGPGCSSVG GGAFTELGPF YPTGDGRGLR LNSMSWNKAS
130 140 150 160 170 180
NLLFVESPAG VGWSYSNRSS DYNTGDKSTV NDMLVFLLRW FNKFPELKSR DLFLTGESYA
190 200 210 220 230 240
GHYIPQLADV ILSYNSRSSG FKFNVKGIAI GNPLLKLDRD FAAAYEYFWS HGMISDEVRL
250 260 270 280 290 300
TIMNQCDFAN PKNMSNACIY AIVESSVLTE YINSYHILLD VCYPSIVQQE LRLKKMNALH
310 320 330 340 350 360
ANRTRLPYEW TMCSNRLNYS GIDGYIDMLP SLKRIIQNQT PVWIFSGDQD SVIPLQSSRT
370 380 390 400 410 420
LVRELAEDLN FKTTIPYGAW FHKEQVGGWV TEYGNLLTFA TVRGAAHMVP YAEPSRALHM
430 440
FSSFMNGRRL PNKPDLKSST DD