Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LY16

Entry ID Method Resolution Chain Position Source
AF-Q9LY16-F1 Predicted AlphaFoldDB

22 variants for Q9LY16

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00610760 7 Q>R No 1000Genomes
ENSVATH10633567 11 H>R No 1000Genomes
ENSVATH00610759 24 I>V No 1000Genomes
tmp_5_2359163_G_A,T 31 L>I No 1000Genomes
tmp_5_2359156_C_T 33 R>K No 1000Genomes
ENSVATH06936726 48 H>Q No 1000Genomes
ENSVATH00610758 49 K>Q No 1000Genomes
tmp_5_2359064_T_C 64 I>V No 1000Genomes
ENSVATH00610755 72 F>Y No 1000Genomes
ENSVATH10633566 75 A>S No 1000Genomes
tmp_5_2358980_A_G 92 F>L No 1000Genomes
ENSVATH00610753 104 S>F No 1000Genomes
ENSVATH06936723 116 V>I No 1000Genomes
ENSVATH06936715 160 T>R No 1000Genomes
tmp_5_2358558_G_C 171 L>V No 1000Genomes
ENSVATH00610752 177 M>T No 1000Genomes
ENSVATH06936714 190 L>S No 1000Genomes
tmp_5_2358470_T_A 200 K>M No 1000Genomes
ENSVATH06936712 200 K>N No 1000Genomes
tmp_5_2358457_G_T 204 D>E No 1000Genomes
tmp_5_2358454_T_G 205 E>D No 1000Genomes
tmp_5_2358450_G_A 207 H>Y No 1000Genomes

No associated diseases with Q9LY16

No regional properties for Q9LY16

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9LY16

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
protein kinase binding Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
regulation of cyclin-dependent protein serine/threonine kinase activity Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P35190 CLG1 PHO85 cyclin CLG1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q84M91 TAN Probable microtubule-binding protein TANGLED Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAYQIDQKMI HDQEPMAEIM PNVITAMSSL LQRVSETNDD LSRPFREHKR ISAFNAVTKP
70 80 90 100 110 120
SISIRSYMER IFKYADCSDS CYIVAYIYLD RFIQKQPLLP IDSSNVHRLI ITSVLVSAKF
130 140 150 160 170 180
MDDLCYNNAF YAKVGGITTE EMNLLELDFL FGIGFQLNVT ISTYNDYCSS LQREMVMRTM
190 200 210
YSPLLEPAFL VRSFHKNLLK NLYDEDHRNS QVTSAV