Q84M91
PR
Gene name |
TAN (ATN, At3g05330, T12H1.30) |
Protein name |
Probable microtubule-binding protein TANGLED |
Names |
AtTAN |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G05330 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q84M91
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q84M91-F1 | Predicted | AlphaFoldDB |
40 variants for Q84M91
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_1521130_C_G | 10 | R>S | No | 1000Genomes | |
| ENSVATH05775254 | 12 | V>L | No | 1000Genomes | |
| tmp_3_1521102_T_C | 20 | N>D | No | 1000Genomes | |
| ENSVATH05775245 | 35 | M>I | No | 1000Genomes | |
| ENSVATH05775244 | 74 | Q>K | No | 1000Genomes | |
| ENSVATH00307180 | 89 | V>L | No | 1000Genomes | |
| ENSVATH13872741 | 92 | F>I | No | 1000Genomes | |
| tmp_3_1520112_C_T | 129 | D>N | No | 1000Genomes | |
| ENSVATH13872737 | 136 | S>G | No | 1000Genomes | |
| ENSVATH10502918 | 138 | K>N | No | 1000Genomes | |
| ENSVATH02114629 | 144 | M>L | No | 1000Genomes | |
| tmp_3_1520048_C_T | 150 | G>D | No | 1000Genomes | |
| ENSVATH00307179 | 169 | S>N | No | 1000Genomes | |
| tmp_3_1519967_T_G | 177 | K>T | No | 1000Genomes | |
| tmp_3_1519931_G_A | 189 | S>F | No | 1000Genomes | |
| ENSVATH00307178 | 209 | V>A | No | 1000Genomes | |
| tmp_3_1519739_G_A | 253 | A>V | No | 1000Genomes | |
| ENSVATH05775226 | 258 | T>I | No | 1000Genomes | |
| tmp_3_1519706_G_T | 264 | A>D | No | 1000Genomes | |
| ENSVATH00307174 | 268 | I>M | No | 1000Genomes | |
| ENSVATH00307173 | 271 | I>S | No | 1000Genomes | |
| ENSVATH05775223 | 279 | Y>H | No | 1000Genomes | |
| tmp_3_1519658_T_C | 280 | K>R | No | 1000Genomes | |
| tmp_3_1519637_G_A | 287 | P>L | No | 1000Genomes | |
| ENSVATH05775221 | 291 | S>T | No | 1000Genomes | |
| ENSVATH00307172 | 294 | Q>R | No | 1000Genomes | |
| ENSVATH00307171 | 298 | R>K | No | 1000Genomes | |
| ENSVATH00307170 | 331 | L>I | No | 1000Genomes | |
| ENSVATH05775220 | 342 | R>I | No | 1000Genomes | |
| ENSVATH05775218 | 344 | T>M | No | 1000Genomes | |
| ENSVATH13872674 | 354 | A>T | No | 1000Genomes | |
| ENSVATH00307169 | 358 | R>G | No | 1000Genomes | |
| ENSVATH05775216 | 373 | K>N | No | 1000Genomes | |
| ENSVATH00307168 | 376 | I>V | No | 1000Genomes | |
| tmp_3_1519353_T_C | 382 | T>A | No | 1000Genomes | |
| ENSVATH05775215 | 398 | K>N | No | 1000Genomes | |
| tmp_3_1519293_C_T | 402 | A>T | No | 1000Genomes | |
| ENSVATH05775213 | 426 | F>L | No | 1000Genomes | |
| ENSVATH05775212 | 435 | F>L | No | 1000Genomes | |
| ENSVATH10502861 | 444 | V>E | No | 1000Genomes |
No associated diseases with Q84M91
No regional properties for Q84M91
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q84M91 | |||
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| microtubule associated complex | Any multimeric complex connected to a microtubule. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| phragmoplast | Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules. |
| preprophase band | A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cytokinesis by cell plate formation | The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana. |
| phragmoplast assembly | The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles). |
| regulation of phragmoplast microtubule organization | Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9LY16 | CYCU4-2 | Cyclin-U4-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVARTPQKQR | KVAMVVPPLN | SDLLKETINK | VDKCMERLQE | LQYTIAGGTK | VVSGVNLSPR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STRIYLKTSL | RCKQETLRIK | NATNKKSPVG | KFPASSPGDW | RKMSLPAMLL | GETVNEILQA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SQVTRDIVDA | IAPKKSRKSR | RLTMSQEDDG | PKTPETQQKS | REQNPETVSS | NIKARRKKEK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QNRRSESDSP | PSLQRARSRI | AFRTISPQVK | GNNGENSFRH | LANRVSPKHK | PWVKKAVLFP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NPLFISGTAT | QQAKFSRTMS | PVIARNEISS | IKNNKETPYK | FLIKSPPTSA | SKFQVKIRSP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PKVLVSPTRN | GSNSVRKSPR | GSRSPTRTVN | LGKKSASISP | IRNTGKRSPK | LSTAAKLRRS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FTPTRNGSNL | ARKSSISPKR | VTLQAFLSPT | RNGNFCKKSP | KASISPTRVC | NKSQKLSTAA |
| 430 | 440 | ||||
| KFRRSFSPSR | LAMRFVSPMK | SRKV |