P35190

PR
Gene name
CLG1 (YGL215W, G1105)
Protein name
PHO85 cyclin CLG1
Names
Cyclin-like G1 protein 1
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YGL215W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

22-152 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P35190

Entry ID Method Resolution Chain Position Source
AF-P35190-F1 Predicted AlphaFoldDB

5 variants for P35190

Variant ID(s) Position Change Description Diseaes Association Provenance
s07-87998 7 Y>H No SGRP
s07-88597 206 N>K No SGRP
s07-88680 234 N>S No SGRP
s07-89033 352 M>V No SGRP
s07-89310 444 N>S No SGRP

No associated diseases with P35190

No regional properties for P35190

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P35190

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cyclin-dependent protein kinase holoenzyme complex Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
cyclin-dependent protein serine/threonine kinase regulator activity Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
protein kinase binding Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.

3 GO annotations of biological process

Name Definition
positive regulation of macroautophagy Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.
regulation of cyclin-dependent protein serine/threonine kinase activity Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9LY16 CYCU4-2 Cyclin-U4-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MANTFKYYPE TMGNSSGYPI SLPFPKGSAT SAVNVARQLP KYLGHVPSQS VHTQLPSMAS
70 80 90 100 110 120
LGYFNQPSST YYAPPAPLQQ HQQPPILPPP GLMYTSNNNS NVIPPPVQMI RDGQQQPQQS
130 140 150 160 170 180
NQVNGGVSEN LDYDISIMSK FIMENAFVAF NANYSTDDQT TDLFFKGISS VLNATRLPSA
190 200 210 220 230 240
TIFLAIDYLF KYINKLSNGI HSIGGNSINI IYQNTMIAFI LANKFNDDKT FTNNSWSQAT
250 260 270 280 290 300
GILINVINDF ERQWLRIFNW ELYDSAFLYF EFVKNFEIFK QNQLKPAVAV PTLLSPIVNV
310 320 330 340 350 360
GDTRNVNFNL KPTSTNNLLS PVSNYETPML MPHNMFSSPS YQSNSRSEFS SMNGYYNYYN
370 380 390 400 410 420
YNQPRLNYYQ QFPNIYSSPI SETQFDYDFY NFSSQQQQQQ QKQHSLLPAA PQLPPPHVHN
430 440 450
QSYGHHLGWK SMDDTINHSR FERNYFPYSA VY