Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LVU3

Entry ID Method Resolution Chain Position Source
AF-Q9LVU3-F1 Predicted AlphaFoldDB

77 variants for Q9LVU3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_19156756_C_G 9 P>R No 1000Genomes
ENSVATH03380356 9 P>S No 1000Genomes
ENSVATH07360721 11 N>Y No 1000Genomes
tmp_5_19156773_A_T 15 R>* No 1000Genomes
ENSVATH12602833 19 V>I No 1000Genomes
tmp_5_19156788_A_T 20 R>* No 1000Genomes
ENSVATH12602834 30 E>Q No 1000Genomes
ENSVATH07360724 33 I>L No 1000Genomes
tmp_5_19156867_A_G 46 D>G No 1000Genomes
tmp_5_19156872_A_G 48 K>E No 1000Genomes
ENSVATH07360725 51 S>C No 1000Genomes
ENSVATH07360726 51 S>I No 1000Genomes
ENSVATH03380357 51 S>R No 1000Genomes
ENSVATH07360727 53 C>F No 1000Genomes
tmp_5_19156915_A_G 62 H>R No 1000Genomes
ENSVATH14605296 80 V>L No 1000Genomes
tmp_5_19156974_A_G 82 N>D No 1000Genomes
tmp_5_19156983_C_A 85 L>I No 1000Genomes
tmp_5_19156997_G_C 89 K>N No 1000Genomes
ENSVATH12602877 91 P>L No 1000Genomes
tmp_5_19157008_C_G 93 S>C No 1000Genomes
tmp_5_19157020_T_A 97 V>D No 1000Genomes
ENSVATH14605297 98 P>S No 1000Genomes
tmp_5_19157082_G_T 118 A>S No 1000Genomes
tmp_5_19157086_A_C 119 Y>S No 1000Genomes
tmp_5_19157098_G_A 123 R>K No 1000Genomes
ENSVATH03380358 125 R>H No 1000Genomes
tmp_5_19157118_C_T 130 P>S No 1000Genomes
tmp_5_19157143_A_C 138 Q>P No 1000Genomes
tmp_5_19157146_A_G 139 K>R No 1000Genomes
ENSVATH07360732 143 S>T No 1000Genomes
ENSVATH07360733 151 N>K No 1000Genomes
ENSVATH07360734 169 S>L No 1000Genomes
tmp_5_19157248_C_T,A 173 A>E No 1000Genomes
ENSVATH12602879 173 A>S No 1000Genomes
tmp_5_19157248_C_T,A 173 A>V No 1000Genomes
tmp_5_19157263_C_G 178 P>R No 1000Genomes
tmp_5_19157274_A_G 182 K>E No 1000Genomes
ENSVATH07360735 186 R>W No 1000Genomes
tmp_5_19157289_T_A 187 S>T No 1000Genomes
tmp_5_19157293_G_A 188 G>E No 1000Genomes
tmp_5_19157298_C_G 190 L>V No 1000Genomes
tmp_5_19157312_A_C 194 Q>H No 1000Genomes
ENSVATH14605299 195 R>* No 1000Genomes
ENSVATH07360736 197 R>Q No 1000Genomes
ENSVATH07360737 198 L>F No 1000Genomes
ENSVATH14605300 211 V>M No 1000Genomes
tmp_5_19157367_C_T 213 R>C No 1000Genomes
tmp_5_19157370_A_G 214 I>V No 1000Genomes
ENSVATH12602881 233 S>L No 1000Genomes
tmp_5_19157482_T_C 251 M>T No 1000Genomes
tmp_5_19157502_C_G 258 Q>E No 1000Genomes
tmp_5_19157539_G_A 270 G>E No 1000Genomes
ENSVATH00716505 270 G>R No 1000Genomes
tmp_5_19157619_A_G 297 K>E No 1000Genomes
ENSVATH14605302 306 I>M No 1000Genomes
tmp_5_19157674_G_A 315 G>E No 1000Genomes
tmp_5_19157673_G_A 315 G>R No 1000Genomes
tmp_5_19157685_A_G 319 I>V No 1000Genomes
tmp_5_19157692_A_C 321 D>A No 1000Genomes
ENSVATH07360740 322 V>M No 1000Genomes
ENSVATH03380359 323 M>I No 1000Genomes
tmp_5_19157724_A_C 332 M>L No 1000Genomes
ENSVATH07360741 334 S>N No 1000Genomes
ENSVATH07360742 334 S>R No 1000Genomes
tmp_5_19157734_A_G 335 K>R No 1000Genomes
ENSVATH03380360 337 H>N No 1000Genomes
tmp_5_19157749_T_A 340 I>N No 1000Genomes
tmp_5_19157766_G_A 346 V>I No 1000Genomes
ENSVATH07360744 361 P>L No 1000Genomes
ENSVATH07360746 366 R>H No 1000Genomes
ENSVATH07360747 368 E>K No 1000Genomes
ENSVATH07360748 379 V>A No 1000Genomes
ENSVATH07360749 388 K>R No 1000Genomes
ENSVATH07360750 393 R>K No 1000Genomes
tmp_5_19157926_T_G 399 I>S No 1000Genomes
ENSVATH14605303 403 F>I No 1000Genomes

No associated diseases with Q9LVU3

1 regional properties for Q9LVU3

Type Name Position InterPro Accession
domain SRA-YDG 257 - 410 IPR003105

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
double-stranded DNA binding Binding to double-stranded DNA.
histone methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.

1 GO annotations of biological process

Name Definition
histone methylation The modification of histones by addition of methyl groups.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9C5P0 SUVH8 Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH8 Arabidopsis thaliana (Mouse-ear cress) PR
Q9T0G7 SUVH9 Histone-lysine N-methyltransferase family member SUVH9 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MMMTQRISPS NKRRRVSFVR DFPQFSVKDE SDIGGDDVAT IKENLDGKED SNCVGVAYRD
70 80 90 100 110 120
HHRPKEESFD SIMKKAGFNV ANGNLGNGKF PPSKRNVPLP CEGKVQPLSV EEGIKLMAYE
130 140 150 160 170 180
SQRRRCFGKP LVSTKVVQKH RYSPAKKKLS NATALRVRHS PMKKLSNASR LRANAHRPTQ
190 200 210 220 230 240
HKDERRSGVL SVIQRNRLSK DLTPRQKVQE VLRIFTLVFD ELDRNKAARR GGSETAKSRI
250 260 270 280 290 300
DYQTWTILRE MGMQVNSQKR IGSVPGIKVG DKIQFKAALS VIGLHFGIMS GIDYMYKGNK
310 320 330 340 350 360
EVATSIVSSE GNDYGDRFIN DVMIYCGQGG NMRSKDHKAI KDQKLVGGNL ALANSIKEKT
370 380 390 400 410
PVRVIRGERR LDNRGKDYVY DGLYRVEKYW EERGPQGNIL FKFKLRRTCQ PYVDF