Q9LR68

PR
Gene name
SCAMP2 (SC2, At1g03550, F21B7.17)
Protein name
Secretory carrier-associated membrane protein 2
Names
AtSC2, Secretory carrier membrane protein 2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G03550
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-107 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LR68

Entry ID Method Resolution Chain Position Source
AF-Q9LR68-F1 Predicted AlphaFoldDB

23 variants for Q9LR68

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH04514238 5 D>H No 1000Genomes
ENSVATH13851168 42 G>D No 1000Genomes
ENSVATH00004317 52 G>R No 1000Genomes
tmp_1_887409_C_T 61 E>K No 1000Genomes
ENSVATH04514234 66 E>D No 1000Genomes
ENSVATH13851167 73 E>G No 1000Genomes
tmp_1_887132_C_T 88 V>I No 1000Genomes
tmp_1_887102_A_T 98 F>I No 1000Genomes
ENSVATH04514233 100 P>S No 1000Genomes
ENSVATH10531342 126 L>S No 1000Genomes
tmp_1_886934_A_C 129 V>G No 1000Genomes
ENSVATH10531341 133 L>F No 1000Genomes
ENSVATH04514230 172 R>C No 1000Genomes
ENSVATH04514227 194 V>M No 1000Genomes
ENSVATH01009264 201 G>S No 1000Genomes
tmp_1_886430_C_T 205 V>I No 1000Genomes
tmp_1_886236_A_T 220 L>* No 1000Genomes
tmp_1_886233_G_T 221 P>Q No 1000Genomes
tmp_1_886227_A_T 223 I>N No 1000Genomes
ENSVATH13851166 241 G>A No 1000Genomes
ENSVATH13851165 259 A>V No 1000Genomes
tmp_1_885923_G_C 260 Y>* No 1000Genomes
tmp_1_885862_G_A 281 R>C No 1000Genomes

No associated diseases with Q9LR68

No regional properties for Q9LR68

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9LR68

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Cytoplasmic vesicle, secretory vesicle membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
recycling endosome membrane The lipid bilayer surrounding a recycling endosome.
trans-Golgi network membrane The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
transport vesicle membrane The lipid bilayer surrounding a transport vesicle.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q969E2 SCAMP4 Secretory carrier-associated membrane protein 4 Homo sapiens (Human) PR
O15126 SCAMP1 Secretory carrier-associated membrane protein 1 Homo sapiens (Human) PR
Q8K021 Scamp1 Secretory carrier-associated membrane protein 1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MARHDPNPFA DEEINPFANH TSVPPASNSY LKPLPPEPYD RGATVDIPLD SGNDLRAKEM
70 80 90 100 110 120
ELQAKENELK RKEQELKRRE DAIARTGVVI EEKNWPEFFP LIHHDIPNEI PIHLQKIQYV
130 140 150 160 170 180
AFTTLLGLVG CLLWNIVAVT VAWIKGEGPT IWLLSIIYFL AGVPGAYVLW YRPLYRATRT
190 200 210 220 230 240
DSALKFGAFF FFYVFHIAFC GFAAVAPPVI FQGKSLTGFL PAIELLTTNA AVGIMYFIGA
250 260 270 280
GFFCIETLLN IWVIQQVYAY FRGSGKAAEM KREATKSTLM RAL