Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LID6

Entry ID Method Resolution Chain Position Source
AF-Q9LID6-F1 Predicted AlphaFoldDB

38 variants for Q9LID6

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_4461255_C_A 23 Q>H No 1000Genomes
tmp_3_4461146_T_A 36 K>N No 1000Genomes
tmp_3_4461147_T_G 36 K>T No 1000Genomes
ENSVATH13911909 50 I>L No 1000Genomes
ENSVATH13911908 82 D>Y No 1000Genomes
ENSVATH05823892 86 R>Q No 1000Genomes
tmp_3_4460719_T_G 122 I>L No 1000Genomes
ENSVATH10657391 125 G>E No 1000Genomes
ENSVATH02140650 129 P>Q No 1000Genomes
tmp_3_4460571_C_T 139 D>N No 1000Genomes
ENSVATH10657389 158 R>Q No 1000Genomes
tmp_3_4460511_C_G 159 V>L No 1000Genomes
ENSVATH02140648 160 V>I No 1000Genomes
ENSVATH05823889 182 G>S No 1000Genomes
ENSVATH13911905 206 L>F No 1000Genomes
ENSVATH00321416 271 V>I No 1000Genomes
tmp_3_4459928_G_T 293 P>Q No 1000Genomes
tmp_3_4459839_G_A 323 R>C No 1000Genomes
tmp_3_4459823_G_A 328 S>F No 1000Genomes
ENSVATH05823883 337 T>R No 1000Genomes
ENSVATH13911864 346 S>F No 1000Genomes
ENSVATH05823882 358 Q>K No 1000Genomes
ENSVATH10657385 373 D>H No 1000Genomes
tmp_3_4459453_G_T 399 P>T No 1000Genomes
tmp_3_4459450_G_T,A 400 R>C No 1000Genomes
tmp_3_4459450_G_T,A 400 R>S No 1000Genomes
tmp_3_4459443_T_A 402 E>V No 1000Genomes
tmp_3_4459438_C_T 404 V>I No 1000Genomes
tmp_3_4459411_C_G 413 V>L No 1000Genomes
tmp_3_4459351_G_C 433 H>D No 1000Genomes
ENSVATH00321414 441 A>T No 1000Genomes
tmp_3_4459291_G_A 453 L>F No 1000Genomes
tmp_3_4459219_T_C 477 T>A No 1000Genomes
ENSVATH10657353 549 A>G No 1000Genomes
ENSVATH00321413 561 H>L No 1000Genomes
tmp_3_4458862_G_T 567 N>K No 1000Genomes
ENSVATH05823879 572 R>L No 1000Genomes
ENSVATH05823878 588 K>* No 1000Genomes

No associated diseases with Q9LID6

9 regional properties for Q9LID6

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 70 - 315 IPR003439-1
domain ABC transporter-like, ATP-binding domain 344 - 566 IPR003439-2
domain AAA+ ATPase domain 102 - 294 IPR003593-1
domain AAA+ ATPase domain 373 - 543 IPR003593-2
domain RNase L inhibitor RLI-like, possible metal-binding domain 6 - 37 IPR007209
conserved_site ABC transporter-like, conserved site 217 - 231 IPR017871
domain 4Fe-4S ferredoxin-type, iron-sulphur binding domain 46 - 75 IPR017896
conserved_site 4Fe-4S ferredoxin, iron-sulphur binding, conserved site 55 - 66 IPR017900
domain RLI, domain 1 78 - 332 IPR034348

Functions

Description
EC Number
Subcellular Localization
  • Membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

4 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
iron ion binding Binding to an iron (Fe) ion.
ribosomal small subunit binding Binding to a small ribosomal subunit.

3 GO annotations of biological process

Name Definition
ribosomal subunit export from nucleus The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
translational termination The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q03195 RLI1 Translation initiation factor RLI1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q8LPJ4 ABCE2 ABC transporter E family member 2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSDRLTRIAI VSEDRCKPKK CRQECKKSCP VVKTGKLCIE VGSTSKSAFI SEELCIGCGI
70 80 90 100 110 120
CVKKCPFEAI QIINLPKDLA KDTTHRYGAN GFKLHRLPIP RPGQVLGLVG TNGIGKSTAL
130 140 150 160 170 180
KILAGKLKPN LGRFNTPPDW EEILTHFRGS ELQSYFIRVV EENLKTAIKP QHVDYIKEVV
190 200 210 220 230 240
RGNLGKMLEK LDERGLMEEI CADMELNQVL EREARQVSGG ELQRFAIAAV FVKKADIYMF
250 260 270 280 290 300
DEPSSYLDVR QRLKAAQVIR SLLRHDSYVI VVEHDLSVLD YLSDFVCCLY GKPGAYGVVT
310 320 330 340 350 360
LPFSVREGIN VFLAGFIPTE NLRFRDESLT FRVSETTQEN DGEVKSYARY KYPNMTKQLG
370 380 390 400 410 420
DFKLEVMEGE FTDSQIIVML GENGTGKTTF IRMLAGAFPR EEGVQSEIPE FNVSYKPQGN
430 440 450 460 470 480
DSKRECTVRQ LLHDKIRDAC AHPQFMSDVI RPLQIEQLMD QVVKTLSGGE KQRVAITLCL
490 500 510 520 530 540
GKPADIYLID EPSAHLDSEQ RITASKVIKR FILHAKKTAF IVEHDFIMAT YLADRVIVYE
550 560 570 580 590 600
GQPAVKCIAH SPQSLLSGMN HFLSHLNITF RRDPTNFRPR INKLESIKDK EQKTAGSYYY
LDD