Q8LPJ4

PR
Gene name
ABCE2 (RLI2, At4g19210, T18B16.180)
Protein name
ABC transporter E family member 2
Names
ABC transporter ABCE.2, AtABCE2, RNase L inhibitor-like protein 2, AtRLI2, AthaRLI2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G19210
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8LPJ4

Entry ID Method Resolution Chain Position Source
AF-Q8LPJ4-F1 Predicted AlphaFoldDB

4 variants for Q8LPJ4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH02880997 44 G>S No 1000Genomes
tmp_4_10503064_C_A 189 D>E No 1000Genomes
tmp_4_10503813_T_C 379 M>T No 1000Genomes
ENSVATH02881004 405 G>A No 1000Genomes

No associated diseases with Q8LPJ4

9 regional properties for Q8LPJ4

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 70 - 315 IPR003439-1
domain ABC transporter-like, ATP-binding domain 344 - 568 IPR003439-2
domain AAA+ ATPase domain 102 - 294 IPR003593-1
domain AAA+ ATPase domain 373 - 546 IPR003593-2
domain RNase L inhibitor RLI-like, possible metal-binding domain 6 - 37 IPR007209
conserved_site ABC transporter-like, conserved site 217 - 231 IPR017871
domain 4Fe-4S ferredoxin-type, iron-sulphur binding domain 46 - 75 IPR017896
conserved_site 4Fe-4S ferredoxin, iron-sulphur binding, conserved site 55 - 66 IPR017900
domain RLI, domain 1 78 - 332 IPR034348

Functions

Description
EC Number
Subcellular Localization
  • Membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

4 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
iron ion binding Binding to an iron (Fe) ion.
ribosomal small subunit binding Binding to a small ribosomal subunit.

3 GO annotations of biological process

Name Definition
ribosomal subunit export from nucleus The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
translational termination The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q03195 RLI1 Translation initiation factor RLI1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q9LID6 ABCE1 ABC transporter E family member 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MADRLTRIAI VSSDRCKPKK CRQECKKSCP VVKTGKLCIE VTVGSKLAFI SEELCIGCGI
70 80 90 100 110 120
CVKKCPFEAI QIINLPRDLE KDTTHRYGAN TFKLHRLPVP RPGQVLGLVG TNGIGKSTAL
130 140 150 160 170 180
KILAGKLKPN LGRFTSPPDW QEILTHFRGS ELQNYFTRIL EDNLKAIIKP QYVDHIPRAV
190 200 210 220 230 240
KGNVGEVLDQ KDERDKKAEL CADLELNQVI DRDVENLSGG ELQRFAIAVV AIQNAEIYMF
250 260 270 280 290 300
DEPSSYLDVK QRLKAAQVVR SLLRPNSYVI VVEHDLSVLD YLSDFICCLY GKPGAYGVVT
310 320 330 340 350 360
LPFSVREGIN IFLAGFVPTE NLRFRDESLT FKVAETPQES AEEIQSYARY KYPTMTKTQG
370 380 390 400 410 420
NFRLRVSEGE FTDSQIIVML GENGTGKTTF IRMLAGLLKP DDTEGPDREI PEFNVSYKPQ
430 440 450 460 470 480
KISPKFQNSV RHLLHQKIRD SYMHPQFMSD VMKPLQIEQL MDQEVVNLSG GELQRVALTL
490 500 510 520 530 540
CLGKPADIYL IDEPSAYLDS EQRIVASKVI KRFILHAKKT AFVVEHDFIM ATYLADRVIV
550 560 570 580 590 600
YEGQPSIDCT ANCPQSLLSG MNLFLSHLNI TFRRDPTNFR PRINKLESTK DREQKSAGSY
YYLDD