Q9LFD1

PR
Gene name
LAC9 (At5g01050, F7J8.30)
Protein name
Laccase-9
Names
Benzenediol:oxygen oxidoreductase 9, Diphenol oxidase 9, Urishiol oxidase 9
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G01050
EC number
1.10.3.2: With oxygen as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

292-398 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LFD1

Entry ID Method Resolution Chain Position Source
AF-Q9LFD1-F1 Predicted AlphaFoldDB

112 variants for Q9LFD1

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_20803_C_A 4 V>F No 1000Genomes
tmp_5_20799_T_C 5 H>R No 1000Genomes
ENSVATH06900449 24 S>* No 1000Genomes
tmp_5_20714_G_C,A 33 H>Q No 1000Genomes
tmp_5_20509_C_T 34 V>I No 1000Genomes
ENSVATH08400020 40 T>K No 1000Genomes
ENSVATH10465629 52 N>D No 1000Genomes
tmp_5_20446_G_A 55 L>F No 1000Genomes
tmp_5_20440_C_T 57 G>S No 1000Genomes
ENSVATH03000259 70 V>I No 1000Genomes
tmp_5_20397_T_C 71 H>R No 1000Genomes
ENSVATH06900436 76 S>* No 1000Genomes
tmp_5_20207_C_T 87 V>I No 1000Genomes
ENSVATH03000250 117 D>E No 1000Genomes
ENSVATH06900433 127 W>* No 1000Genomes
tmp_5_20083_T_C 128 H>R No 1000Genomes
tmp_5_20069_T_G 133 N>H No 1000Genomes
ENSVATH10465603 138 I>L No 1000Genomes
tmp_5_20029_G_T 146 P>H No 1000Genomes
tmp_5_19992_G_T 158 Y>* No 1000Genomes
ENSVATH10465602 161 V>F No 1000Genomes
ENSVATH13863211 162 P>S No 1000Genomes
ENSVATH03000247 169 W>L No 1000Genomes
tmp_5_19660_C_T 173 V>I No 1000Genomes
ENSVATH10465557 178 L>Q No 1000Genomes
tmp_5_19587_T_A 197 Y>F No 1000Genomes
tmp_5_19579_A_G 200 S>P No 1000Genomes
tmp_5_19576_T_A,C 201 K>* No 1000Genomes
tmp_5_19576_T_A,C 201 K>E No 1000Genomes
ENSVATH10465501 204 M>L No 1000Genomes
ENSVATH13863209 209 V>D No 1000Genomes
ENSVATH10465500 211 Q>E No 1000Genomes
tmp_5_19412_G_T 215 Y>* No 1000Genomes
ENSVATH10465473 220 I>V No 1000Genomes
tmp_5_19374_A_G 228 L>P No 1000Genomes
tmp_5_19360_C_T 233 A>T No 1000Genomes
tmp_5_19351_T_C 236 N>D No 1000Genomes
tmp_5_19345_T_A 238 T>S No 1000Genomes
ENSVATH03000244 247 T>S No 1000Genomes
tmp_5_19302_G_A 252 T>I No 1000Genomes
ENSVATH13863208 258 T>I No 1000Genomes
ENSVATH03000243 269 A>G No 1000Genomes
ENSVATH10465471 277 Y>N No 1000Genomes
ENSVATH10465469 287 I>T No 1000Genomes
tmp_5_19192_C_T 289 V>I No 1000Genomes
tmp_5_19183_A_T 292 S>T No 1000Genomes
tmp_5_19173_G_A 295 T>I No 1000Genomes
ENSVATH03000242 297 P>S No 1000Genomes
ENSVATH06900423 301 L>* No 1000Genomes
tmp_5_19144_CG_GG,C 304 Y>* No 1000Genomes
tmp_5_19144_CG_GG,C 305 E>Q No 1000Genomes
ENSVATH10465468 306 G>S No 1000Genomes
tmp_5_19134_G_A 308 T>M No 1000Genomes
ENSVATH03000241 313 P>S No 1000Genomes
tmp_5_19117_T_C 314 T>A No 1000Genomes
ENSVATH03000240 314 T>K No 1000Genomes
tmp_5_19114_T_C 315 K>E No 1000Genomes
tmp_5_19107_C_A 317 W>L No 1000Genomes
ENSVATH13863207 318 M>T No 1000Genomes
tmp_5_19101_G_C 319 P>R No 1000Genomes
tmp_5_19099_G_C 320 P>A No 1000Genomes
tmp_5_19098_G_A 320 P>L No 1000Genomes
tmp_5_19096_C_G 321 A>P No 1000Genomes
tmp_5_19090_C_T 323 D>N No 1000Genomes
tmp_5_19085_T_C 324 I>M No 1000Genomes
ENSVATH03000239 325 P>S No 1000Genomes
ENSVATH10465467 328 H>Y No 1000Genomes
ENSVATH10465466 334 I>V No 1000Genomes
ENSVATH00806027 348 R>H No 1000Genomes
tmp_5_18997_T_C 354 M>V No 1000Genomes
tmp_5_18972_A_C 362 L>* No 1000Genomes
tmp_5_18962_A_T 365 C>* No 1000Genomes
tmp_5_18958_A_C 367 S>A No 1000Genomes
tmp_5_18955_T_C 368 N>D No 1000Genomes
tmp_5_18954_T_C 368 N>S No 1000Genomes
tmp_5_18952_C_T 369 A>T No 1000Genomes
tmp_5_18943_C_T 372 V>I No 1000Genomes
tmp_5_18930_TC_CC,T 376 D>G No 1000Genomes
ENSVATH03000238 378 R>K No 1000Genomes
ENSVATH10465441 379 L>F No 1000Genomes
ENSVATH03000237 405 T>S No 1000Genomes
ENSVATH06900421 408 Y>* No 1000Genomes
tmp_5_18826_C_G 411 D>H No 1000Genomes
tmp_5_18778_G_A 427 Q>* No 1000Genomes
ENSVATH10465437 428 H>Y No 1000Genomes
ENSVATH13863205 444 S>I No 1000Genomes
ENSVATH13863154 452 S>F No 1000Genomes
ENSVATH06900420 455 E>D No 1000Genomes
tmp_5_18684_A_G 458 L>S No 1000Genomes
ENSVATH10465394 462 G>A No 1000Genomes
tmp_5_18667_G_T 464 L>I No 1000Genomes
ENSVATH06900418 490 P>L No 1000Genomes
ENSVATH06900419 490 P>S No 1000Genomes
ENSVATH03000235 497 L>F No 1000Genomes
ENSVATH00806026 503 Q>* No 1000Genomes
tmp_5_18544_G_C 505 H>D No 1000Genomes
tmp_5_18511_C_A 516 V>F No 1000Genomes
ENSVATH06900416 521 I>T No 1000Genomes
ENSVATH10465387 527 I>V No 1000Genomes
tmp_5_18363_G_C 536 A>G No 1000Genomes
ENSVATH10465386 538 L>* No 1000Genomes
ENSVATH06900414 539 P>Q No 1000Genomes
tmp_5_18341_C_G 543 M>I No 1000Genomes
ENSVATH10465385 553 T>S No 1000Genomes
tmp_5_18279_T_C 564 N>S No 1000Genomes
tmp_5_18264_G_C 569 T>S No 1000Genomes
tmp_5_18244_C_T 576 D>N No 1000Genomes
tmp_5_18237_C_T 578 R>Q No 1000Genomes
ENSVATH13863153 579 T>M No 1000Genomes
ENSVATH10465343 580 T>N No 1000Genomes
tmp_5_18226_C_T 582 V>I No 1000Genomes
tmp_5_18220_T_A 584 M>L No 1000Genomes

No associated diseases with Q9LFD1

6 regional properties for Q9LFD1

Type Name Position InterPro Accession
domain Multicopper oxidase, second cupredoxin domain 160 - 307 IPR001117
domain Multicopper oxidase, C-terminal 412 - 550 IPR011706
domain Multicopper oxidase, N-terminal 34 - 148 IPR011707
domain Laccase, second cupredoxin domain 161 - 304 IPR034285
domain Laccase, first cupredoxin domain 30 - 146 IPR034288
domain Laccase, third cupredoxin domain 407 - 551 IPR034289

Functions

Description
EC Number 1.10.3.2 With oxygen as acceptor
Subcellular Localization
  • Secreted, extracellular space, apoplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
apoplast The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.

3 GO annotations of molecular function

Name Definition
copper ion binding Binding to a copper (Cu) ion.
hydroquinone:oxygen oxidoreductase activity Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

1 GO annotations of biological process

Name Definition
lignin catabolic process The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2R0L0 LAC20 Laccase-20 Oryza sativa subsp japonica (Rice) PR
Q2R0L2 LAC19 Laccase-19 Oryza sativa subsp japonica (Rice) PR
Q5N7A3 LAC6 Laccase-6 Oryza sativa subsp japonica (Rice) PR
Q6ID18 LAC10 Laccase-10 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZA1 LAC11 Laccase-11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY79 LAC14 Laccase-14 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LFD2 LAC8 Laccase-8 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MPRVHHSLSN QAFLVLLLFS SIASAAIVEH VLHVKDVVVT PLCKEQMIPI VNGSLPGPTI
70 80 90 100 110 120
NVREGDTLVV HVINKSTYNV TIHWHGVFQL KSVWMDGANM ITQCPIQPSN NFTYQFDITG
130 140 150 160 170 180
QEGTLLWHAH VVNLRATIHG ALIIRPRSGR PYPFPKPYKE VPLIFQQWWD TDVRLLELRP
190 200 210 220 230 240
APVSDAYLIN GLAGDSYPCS KNRMFNLKVV QGKTYLLRII NAALNTHLFF KIANHNVTVV
250 260 270 280 290 300
AVDAVYTTPY LTDVMILTPG QTIDAILTAD QPIGTYYMAI IPYFSAIGVP ASPDTKPTRG
310 320 330 340 350 360
LIVYEGATSS SSPTKPWMPP ANDIPTAHRF SSNITSLVGG PHWTPVPRHV DEKMFITMGL
370 380 390 400 410 420
GLDPCPSNAK CVGPLDQRLA GSLNNRTFMI PERISMQEAY FYNITGVYTD DFPDQPPLKF
430 440 450 460 470 480
DFTKFEQHPT NSDMEMMFPE RKTSVKTIRF NSTVEIVLQN TGILTPESHP MHLHGFNFYV
490 500 510 520 530 540
LGYGFGNYDP IRDARKLNLF NPQMHNTVGV PPGGWVVLRF IANNPGIWLF HCHMDAHLPL
550 560 570 580
GIMMAFIVQN GPTRETSLPS PPSNLPQCTR DPTIYDSRTT NVDMSY