Q9JJ09
Gene name |
Slc34a2 |
Protein name |
Sodium-dependent phosphate transport protein 2B |
Names |
Sodium-phosphate transport protein 2B, Na(+)-dependent phosphate cotransporter 2B, Sodium/phosphate cotransporter 2B, Na(+)/Pi cotransporter 2B, NaPi-2b, Solute carrier family 34 member 2, rNaPi IIb |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:84395 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9JJ09
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9JJ09-F1 | Predicted | AlphaFoldDB |
No variants for Q9JJ09
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9JJ09 | |||||
No associated diseases with Q9JJ09
No regional properties for Q9JJ09
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9JJ09 | |||
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| apical plasma membrane | The region of the plasma membrane located at the apical end of the cell. |
| brush border | The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell. |
| brush border membrane | The portion of the plasma membrane surrounding the brush border. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| microvillus membrane | The portion of the plasma membrane surrounding a microvillus. |
| vesicle | Any small, fluid-filled, spherical organelle enclosed by membrane. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphate ion binding | Binding to a phosphate ion. |
| protein domain specific binding | Binding to a specific domain of a protein. |
| sodium ion binding | Binding to a sodium ion (Na+). |
| sodium:phosphate symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in). |
9 GO annotations of biological process
| Name | Definition |
|---|---|
| aging | A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700). |
| cellular phosphate ion homeostasis | Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell. |
| in utero embryonic development | The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. |
| phosphate ion transport | The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| response to estradiol | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. |
| response to estrogen | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. |
| response to fructose | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus. |
| sodium ion transmembrane transport | A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
| sodium-dependent phosphate transport | The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPWPELENA | HPNPNKFIEG | ASGPQSSIPD | KDKGTSKTND | SGTPVAKIEL | LPSYSALVLI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EEPPEGNDPW | DLPELQDNGI | KWSERDSKGK | ILCIFQGIGK | FILLLGFLYL | FVCSLDVLSS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AFQLVGGKMA | GQFFSNNSIM | SNPVAGLVIG | VLVTVMVQSS | STSSSIIVSM | VASSLLSVRA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AIPIIMGANI | GTSITNTIVA | LMQAGDRNEF | RRAFAGATVH | DFFNWLSVLV | LLPLEAATHY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LEKLTNLVLE | TFSFQNGEDA | PDILKVITDP | FTKLIIQLDK | KVIQQIAMGD | SEAQNKSLIK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IWCKTISNVI | EENVTVPSPD | NCTSPSYCWT | DGIQTWTIQN | VTEKENIAKC | QHIFVNFSLP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DLAVGIILLT | VSLLILCGCL | IMIVKLLGSV | LRGQVATVIK | KTLNTDFPFP | FAWLTGYLAI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LVGAGMTFIV | QSSSVFTSAM | TPLIGIGVIS | IERAYPLTLG | SNIGTTTTAI | LAALASPGNT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LRSSLQIALC | HFFFNISGIL | LWYPIPFTRL | PIRLAKGLGN | ISAKYRWFAV | FYLIFFFLLT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PLTVFGLSLA | GWPVLVGVGV | PIILLILLVL | CLRMLQARCP | RILPLKLRDW | NFLPLWMHSL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KPWDNIISLA | TSCFQRRCCC | CCRVCCRVCC | MVCGCKCCRC | SKCCKNLEEE | EKEQDVPVKA |
| 670 | 680 | 690 | |||
| SGGFDNTAMS | KECQDEGKGQ | VEVLGMKALS | NTTVF |