AiPD: Autoinhibited Protein Database

Gene name	STT3B (At1g34130, F12G12.5)
Protein name	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B
Names	Oligosaccharyl transferase subunit STT3B, STT3-B, Protein STAUROSPORIN AND TEMPERATURE SENSITIVE 3-LIKE B
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT1G34130
EC number	2.4.99.18: Transferring other glycosyl groups
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-62 (Predicted disordered autoinhibitory region) PR

1-62 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9FX21-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH12823732	13	M>I	No	1000Genomes
tmp_1_12430055_T_C	19	L>P	No	1000Genomes
ENSVATH04724067	20	L>R	No	1000Genomes
tmp_1_12430061_A_T	21	N>I	No	1000Genomes
ENSVATH00064120	23	S>R	No	1000Genomes
ENSVATH14067924	29	S>P	No	1000Genomes
tmp_1_12430430_C_T	144	P>L	No	1000Genomes
tmp_1_12430480_C_G	161	L>V	No	1000Genomes
tmp_1_12430492_G_A	165	G>R	No	1000Genomes
ENSVATH12823865	291	M>I	No	1000Genomes
tmp_1_12430877_C_G	293	A>G	No	1000Genomes
tmp_1_12430895_T_C	299	L>S	No	1000Genomes
ENSVATH12823868	302	V>M	No	1000Genomes
tmp_1_12430917_G_T	306	L>F	No	1000Genomes
ENSVATH12823869	307	D>E	No	1000Genomes
tmp_1_12430930_T_C	311	Y>H	No	1000Genomes
tmp_1_12430946_C_T	316	T>I	No	1000Genomes
tmp_1_12430960_A_G	321	T>A	No	1000Genomes
tmp_1_12430987_G_A	330	A>T	No	1000Genomes
ENSVATH12823872	332	L>F	No	1000Genomes
ENSVATH12823874	337	A>T	No	1000Genomes
ENSVATH12823895	338	V>L	No	1000Genomes
tmp_1_12431212_C_T	405	R>C	No	1000Genomes
tmp_1_12431272_G_A	425	G>S	No	1000Genomes
tmp_1_12431347_A_G	450	I>V	No	1000Genomes
ENSVATH00064126	463	V>G	No	1000Genomes
ENSVATH04724075	465	Q>L	No	1000Genomes
ENSVATH00064127	469	T>M	No	1000Genomes
ENSVATH04724076	474	S>G	No	1000Genomes
tmp_1_12431437_A_C	480	K>Q	No	1000Genomes
tmp_1_12431579_G_C	487	Q>H	No	1000Genomes
tmp_1_12431586_C_G	490	Q>E	No	1000Genomes
ENSVATH12823960	499	V>L	No	1000Genomes
tmp_1_12431727_A_G	537	I>V	No	1000Genomes
tmp_1_12431899_G_A	594	R>H	No	1000Genomes
ENSVATH00064131	602	D>E	No	1000Genomes
tmp_1_12432739_C_A	684	L>M	No	1000Genomes
tmp_1_12432893_G_A	706	D>N	No	1000Genomes
ENSVATH12824169	727	R>K	No	1000Genomes
tmp_1_12432969_C_T	731	P>L	No	1000Genomes

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q9FX21

		Description
EC Number	2.4.99.18	Transferring other glycosyl groups
Subcellular Localization	Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
metal ion binding	Binding to a metal ion.

Name	Definition
protein glycosylation	A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P39007	STT3	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
Q2KJI2	STT3A	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	Bos taurus (Bovine)	PR
Q8TCJ2	STT3B	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	Homo sapiens (Human)	PR
P46977	STT3A	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	Homo sapiens (Human)	PR
P46978	Stt3a	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	Mus musculus (Mouse)	PR
Q3TDQ1	Stt3b	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	Mus musculus (Mouse)	PR
Q7XQ88	STT3B	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	Oryza sativa subsp japonica (Rice)	PR
P46975	stt-3	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt-3	Caenorhabditis elegans	PR
Q93ZY3	STT3A	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	Arabidopsis thaliana (Mouse-ear cress)	PR