AiPD: Autoinhibited Protein Database

Gene name	STT3A (At5g19690, T29J13_110)
Protein name	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Names	Oligosaccharyl transferase subunit STT3A, STT3-A, Integral membrane protein 1, Protein STAUROSPORIN AND TEMPERATURE SENSITIVE 3-LIKE A
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT5G19690
EC number	2.4.99.18: Transferring other glycosyl groups
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

440-521 (Predicted disordered autoinhibitory region) PR

440-521 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q93ZY3-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH10866226	2	A>T	No	1000Genomes
ENSVATH06997433	6	S>G	No	1000Genomes
ENSVATH00632735	8	L>Q	No	1000Genomes
ENSVATH10866227	10	G>E	No	1000Genomes
tmp_5_6652734_T_C	29	V>A	No	1000Genomes
tmp_5_6652733_G_T	29	V>F	No	1000Genomes
ENSVATH00632743	103	T>S	No	1000Genomes
tmp_5_6653804_G_A	132	A>T	No	1000Genomes
tmp_5_6654686_C_A	229	L>I	No	1000Genomes
ENSVATH06997475	314	V>M	No	1000Genomes
tmp_5_6656089_C_T	388	S>L	No	1000Genomes
ENSVATH06997479	448	S>L	No	1000Genomes
ENSVATH03081895	448	S>T	No	1000Genomes
tmp_5_6656486_A_G	458	N>S	No	1000Genomes
ENSVATH03081897	469	V>A	No	1000Genomes
ENSVATH03081898	470	S>A	No	1000Genomes
ENSVATH03081899	472	G>S	No	1000Genomes
tmp_5_6656543_G_A	477	G>D	No	1000Genomes
tmp_5_6656542_G_A	477	G>S	No	1000Genomes
ENSVATH06997482	481	V>L	No	1000Genomes
ENSVATH14097974	497	A>T	No	1000Genomes
tmp_5_6656677_C_T	522	L>F	No	1000Genomes
ENSVATH10866436	627	W>S	No	1000Genomes
tmp_5_6657271_G_T	641	V>F	No	1000Genomes
ENSVATH10866437	647	G>D	No	1000Genomes
ENSVATH06997492	689	P>S	No	1000Genomes
tmp_5_6657770_A_G	718	T>A	No	1000Genomes
tmp_5_6657967_A_G	756	K>R	No	1000Genomes
tmp_5_6657979_T_C	760	L>P	No	1000Genomes

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q93ZY3

		Description
EC Number	2.4.99.18	Transferring other glycosyl groups
Subcellular Localization	Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plastid	Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

Name	Definition
dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
metal ion binding	Binding to a metal ion.

Name	Definition
protein glycosylation	A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
regulation of response to osmotic stress	Any process that modulates the rate or extent of the response to osmotic stress.
response to salt stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P39007	STT3	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
Q2KJI2	STT3A	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	Bos taurus (Bovine)	PR
Q8TCJ2	STT3B	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	Homo sapiens (Human)	PR
P46977	STT3A	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	Homo sapiens (Human)	PR
P46978	Stt3a	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	Mus musculus (Mouse)	PR
Q3TDQ1	Stt3b	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	Mus musculus (Mouse)	PR
Q7XQ88	STT3B	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	Oryza sativa subsp japonica (Rice)	PR
P46975	stt-3	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt-3	Caenorhabditis elegans	PR
Q9FX21	STT3B	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	Arabidopsis thaliana (Mouse-ear cress)	PR