Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FWY9

Entry ID Method Resolution Chain Position Source
AF-Q9FWY9-F1 Predicted AlphaFoldDB

20 variants for Q9FWY9

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01006694 41 D>E No 1000Genomes
ENSVATH04509667 52 S>T No 1000Genomes
ENSVATH13850009 55 R>K No 1000Genomes
ENSVATH00003121 61 R>H No 1000Genomes
ENSVATH10496688 69 S>P No 1000Genomes
ENSVATH04509668 71 E>D No 1000Genomes
tmp_1_592404_C_G 97 A>G No 1000Genomes
ENSVATH04509669 97 A>S No 1000Genomes
ENSVATH13850010 99 V>A No 1000Genomes
ENSVATH04509670 99 V>I No 1000Genomes
ENSVATH04509671 134 P>L No 1000Genomes
tmp_1_592534_A_C 140 K>N No 1000Genomes
ENSVATH10496689 216 H>L No 1000Genomes
tmp_1_592771_C_A 219 F>L No 1000Genomes
tmp_1_592782_T_A 223 F>Y No 1000Genomes
ENSVATH00003125 231 K>E No 1000Genomes
tmp_1_592826_A_G 238 K>E No 1000Genomes
ENSVATH00003127 259 Q>R No 1000Genomes
ENSVATH01006699 275 I>M No 1000Genomes
ENSVATH13850012 350 L>F No 1000Genomes

No associated diseases with Q9FWY9

No regional properties for Q9FWY9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FWY9

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
polygalacturonate 4-alpha-galacturonosyltransferase activity Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.

4 GO annotations of biological process

Name Definition
mucilage biosynthetic process involved in seed coat development The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.
mucilage pectin metabolic process The chemical reactions and pathways involving the pectin component of mucilage.
pectin biosynthetic process The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.
plant-type cell wall assembly The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9H1C3 GLT8D2 Glycosyltransferase 8 domain-containing protein 2 Homo sapiens (Human) PR
Q9FH36 GAUT12 Probable galacturonosyltransferase 12 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LE59 GAUT1 Polygalacturonate 4-alpha-galacturonosyltransferase Arabidopsis thaliana (Mouse-ear cress) PR
Q28I33 glt8d1 Glycosyltransferase 8 domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MHWITRFSAF FSAALAMILL SPSLQSFSPA AAIRSSHPYA DEFKPQQNSD YSSFRESPMF
70 80 90 100 110 120
RNAEQCRSSG EDSGVCNPNL VHVAITLDID YLRGSIAAVN SILQHSMCPQ SVFFHFLVSS
130 140 150 160 170 180
ESQNLESLIR STFPKLTNLK IYYFAPETVQ SLISSSVRQA LEQPLNYARN YLADLLEPCV
190 200 210 220 230 240
KRVIYLDSDL VVVDDIVKLW KTGLGQRTIG APEYCHANFT KYFTGGFWSD KRFNGTFKGR
250 260 270 280 290 300
NPCYFNTGVM VIDLKKWRQF RFTKRIEKWM EIQKIERIYE LGSLPPFLLV FAGHVAPISH
310 320 330 340 350 360
RWNQHGLGGD NVRGSCRDLH SGPVSLLHWS GSGKPWLRLD SKLPCPLDTL WAPYDLYKHS
H