Q9FH36

PR
Gene name
GAUT12 (IRX8, LGT6, At5g54690, K5F14.3)
Protein name
Probable galacturonosyltransferase 12
Names
Like glycosyl transferase 6, Protein IRREGULAR XYLEM 8
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G54690
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

75-166 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FH36

Entry ID Method Resolution Chain Position Source
AF-Q9FH36-F1 Predicted AlphaFoldDB

34 variants for Q9FH36

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_22221759_T_G 4 H>P No 1000Genomes
ENSVATH12768322 13 T>I No 1000Genomes
ENSVATH12768321 26 V>F No 1000Genomes
ENSVATH03430045 33 F>L No 1000Genomes
tmp_5_22221075_G_T 78 L>I No 1000Genomes
ENSVATH12768286 83 L>F No 1000Genomes
ENSVATH12768285 88 D>V No 1000Genomes
ENSVATH00734302 105 S>R No 1000Genomes
tmp_5_22220866_T_C 115 I>V No 1000Genomes
tmp_5_22220847_T_G 121 D>A No 1000Genomes
tmp_5_22220806_C_G 135 E>Q No 1000Genomes
ENSVATH14632768 142 E>Q No 1000Genomes
tmp_5_22220751_G_A 153 T>M No 1000Genomes
ENSVATH03430024 174 H>Y No 1000Genomes
ENSVATH14632765 177 A>V No 1000Genomes
ENSVATH03430020 196 E>K No 1000Genomes
ENSVATH14632764 206 N>S No 1000Genomes
ENSVATH03430015 230 Q>K No 1000Genomes
ENSVATH12768227 235 P>R No 1000Genomes
ENSVATH12768228 235 P>S No 1000Genomes
tmp_5_22220502_T_C 236 H>R No 1000Genomes
tmp_5_22220425_A_T 262 S>T No 1000Genomes
tmp_5_22220415_A_T 265 I>K No 1000Genomes
tmp_5_22220299_C_G 304 V>L No 1000Genomes
ENSVATH12768214 368 D>A No 1000Genomes
ENSVATH03430008 408 N>D No 1000Genomes
tmp_5_22219895_T_G 411 E>D No 1000Genomes
tmp_5_22219830_G_A 433 S>F No 1000Genomes
ENSVATH03430006 437 H>Y No 1000Genomes
tmp_5_22219583_G_A 487 A>V No 1000Genomes
tmp_5_22219463_A_G 527 I>T No 1000Genomes
tmp_5_22219451_T_A 531 H>L No 1000Genomes
tmp_5_22219446_T_C 533 R>G No 1000Genomes
tmp_5_22219444_T_A 533 R>S No 1000Genomes

No associated diseases with Q9FH36

No regional properties for Q9FH36

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FH36

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
polygalacturonate 4-alpha-galacturonosyltransferase activity Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.

5 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
glucuronoxylan biosynthetic process The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues.
glucuronoxylan metabolic process The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units.
pectin biosynthetic process The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.
xylan biosynthetic process The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9H1C3 GLT8D2 Glycosyltransferase 8 domain-containing protein 2 Homo sapiens (Human) PR
Q9FWY9 GATL5 Probable galacturonosyltransferase-like 5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LE59 GAUT1 Polygalacturonate 4-alpha-galacturonosyltransferase Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MQLHISPSLR HVTVVTGKGL REFIKVKVGS RRFSYQMVFY SLLFFTFLLR FVFVLSTVDT
70 80 90 100 110 120
IDGDPSPCSS LACLGKRLKP KLLGRRVDSG NVPEAMYQVL EQPLSEQELK GRSDIPQTLQ
130 140 150 160 170 180
DFMSEVKRSK SDAREFAQKL KEMVTLMEQR TRTAKIQEYL YRHVASSSIP KQLHCLALKL
190 200 210 220 230 240
ANEHSINAAA RLQLPEAELV PMLVDNNYFH FVLASDNILA ASVVAKSLVQ NALRPHKIVL
250 260 270 280 290 300
HIITDRKTYF PMQAWFSLHP LSPAIIEVKA LHHFDWLSKG KVPVLEAMEK DQRVRSQFRG
310 320 330 340 350 360
GSSVIVANNK ENPVVVAAKL QALSPKYNSL MNHIRIHLPE LFPSLNKVVF LDDDIVIQTD
370 380 390 400 410 420
LSPLWDIDMN GKVNGAVETC RGEDKFVMSK KFKSYLNFSN PTIAKNFNPE ECAWAYGMNV
430 440 450 460 470 480
FDLAAWRRTN ISSTYYHWLD ENLKSDLSLW QLGTLPPGLI AFHGHVQTID PFWHMLGLGY
490 500 510 520 530
QETTSYADAE SAAVVHFNGR AKPWLDIAFP HLRPLWAKYL DSSDRFIKSC HIRAS