Q9FNA4
PR
Gene name |
ELP1 (ABO1, ELO2, At5g13680, MSH12.15) |
Protein name |
Elongator complex protein 1 |
Names |
AtELP1, Elongator component 1, Protein ABA-OVERLY SENSITIVE 1, Protein ELONGATA 2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G13680 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FNA4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FNA4-F1 | Predicted | AlphaFoldDB |
87 variants for Q9FNA4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_4415457_C_G | 5 | K>N | No | 1000Genomes | |
| tmp_5_4415455_A_C | 6 | L>R | No | 1000Genomes | |
| ENSVATH10734198 | 24 | Q>R | No | 1000Genomes | |
| ENSVATH06963672 | 33 | S>R | No | 1000Genomes | |
| ENSVATH06963671 | 44 | V>I | No | 1000Genomes | |
| ENSVATH14019580 | 65 | V>A | No | 1000Genomes | |
| ENSVATH03053993 | 102 | H>Y | No | 1000Genomes | |
| ENSVATH00620747 | 125 | N>S | No | 1000Genomes | |
| ENSVATH14019579 | 156 | G>A | No | 1000Genomes | |
| ENSVATH00620745 | 167 | T>A | No | 1000Genomes | |
| tmp_5_4414600_C_G | 172 | V>L | No | 1000Genomes | |
| tmp_5_4414568_C_A | 182 | R>S | No | 1000Genomes | |
| tmp_5_4414518_C_A | 199 | C>F | No | 1000Genomes | |
| ENSVATH06963667 | 212 | G>S | No | 1000Genomes | |
| tmp_5_4414440_T_A | 225 | Q>L | No | 1000Genomes | |
| tmp_5_4414416_C_G | 233 | S>T | No | 1000Genomes | |
| tmp_5_4414396_C_T | 240 | V>I | No | 1000Genomes | |
| tmp_5_4414392_T_C | 241 | Y>C | No | 1000Genomes | |
| tmp_5_4414336_G_A | 260 | L>F | No | 1000Genomes | |
| ENSVATH00620744 | 263 | S>C | No | 1000Genomes | |
| ENSVATH14019578 | 298 | Y>F | No | 1000Genomes | |
| ENSVATH14019576 | 324 | G>W | No | 1000Genomes | |
| tmp_5_4414069_G_A | 349 | R>C | No | 1000Genomes | |
| ENSVATH00620743 | 357 | V>I | No | 1000Genomes | |
| tmp_5_4413997_C_T | 373 | V>M | No | 1000Genomes | |
| tmp_5_4413980_C_A | 378 | L>F | No | 1000Genomes | |
| tmp_5_4413967_G_A | 383 | P>S | No | 1000Genomes | |
| tmp_5_4413916_C_T | 400 | A>T | No | 1000Genomes | |
| tmp_5_4413822_T_G | 431 | E>A | No | 1000Genomes | |
| tmp_5_4413762_G_A | 451 | S>F | No | 1000Genomes | |
| ENSVATH03053992 | 481 | G>A | No | 1000Genomes | |
| tmp_5_4413653_A_T | 487 | H>Q | No | 1000Genomes | |
| ENSVATH03053991 | 489 | S>F | No | 1000Genomes | |
| ENSVATH06963664 | 515 | S>R | No | 1000Genomes | |
| ENSVATH00620742 | 535 | K>N | No | 1000Genomes | |
| tmp_5_4413450_G_A | 555 | S>L | No | 1000Genomes | |
| ENSVATH00620741 | 557 | I>L | No | 1000Genomes | |
| tmp_5_4413442_T_G | 558 | M>L | No | 1000Genomes | |
| tmp_5_4413438_T_C | 559 | E>G | No | 1000Genomes | |
| ENSVATH03053990 | 570 | P>S | No | 1000Genomes | |
| tmp_5_4413402_G_A | 571 | S>L | No | 1000Genomes | |
| tmp_5_4413367_C_T | 583 | A>T | No | 1000Genomes | |
| tmp_5_4413303_C_T | 604 | G>E | No | 1000Genomes | |
| ENSVATH00620740 | 647 | N>K | No | 1000Genomes | |
| ENSVATH00620739 | 664 | R>Q | No | 1000Genomes | |
| ENSVATH06963661 | 668 | N>S | No | 1000Genomes | |
| tmp_5_4413099_A_G | 672 | V>A | No | 1000Genomes | |
| tmp_5_4412965_C_A | 717 | A>S | No | 1000Genomes | |
| tmp_5_4412760_T_A | 785 | K>M | No | 1000Genomes | |
| tmp_5_4412709_C_T | 802 | C>Y | No | 1000Genomes | |
| ENSVATH06963659 | 804 | N>D | No | 1000Genomes | |
| tmp_5_4412679_G_C | 812 | A>G | No | 1000Genomes | |
| ENSVATH06963658 | 819 | E>K | No | 1000Genomes | |
| tmp_5_4412618_C_A | 832 | L>F | No | 1000Genomes | |
| ENSVATH06963657 | 837 | R>Q | No | 1000Genomes | |
| tmp_5_4412596_G_C | 840 | P>A | No | 1000Genomes | |
| tmp_5_4412587_T_A | 843 | I>F | No | 1000Genomes | |
| ENSVATH06963655 | 862 | S>F | No | 1000Genomes | |
| tmp_5_4412508_G_A | 869 | S>F | No | 1000Genomes | |
| ENSVATH10734151 | 922 | E>K | No | 1000Genomes | |
| tmp_5_4412336_C_G | 926 | M>I | No | 1000Genomes | |
| tmp_5_4412257_C_T | 953 | G>R | No | 1000Genomes | |
| ENSVATH00620736 | 960 | C>S | No | 1000Genomes | |
| ENSVATH06963653 | 973 | L>V | No | 1000Genomes | |
| ENSVATH00620734 | 1002 | E>V | No | 1000Genomes | |
| ENSVATH00620732 | 1026 | D>N | No | 1000Genomes | |
| tmp_5_4412031_C_A | 1028 | S>I | No | 1000Genomes | |
| tmp_5_4412014_C_A | 1034 | G>W | No | 1000Genomes | |
| tmp_5_4411971_G_A | 1048 | A>V | No | 1000Genomes | |
| ENSVATH06963651 | 1050 | E>G | No | 1000Genomes | |
| ENSVATH00620731 | 1089 | E>Q | No | 1000Genomes | |
| tmp_5_4411805_T_A | 1103 | R>S | No | 1000Genomes | |
| tmp_5_4411624_T_A | 1164 | T>S | No | 1000Genomes | |
| tmp_5_4411574_C_A | 1180 | L>F | No | 1000Genomes | |
| tmp_5_4410994_T_G | 1191 | S>R | No | 1000Genomes | |
| ENSVATH00620726 | 1203 | R>K | No | 1000Genomes | |
| ENSVATH06963641 | 1224 | D>N | No | 1000Genomes | |
| tmp_5_4410794_G_A | 1230 | R>C | No | 1000Genomes | |
| ENSVATH00620724 | 1230 | R>H | No | 1000Genomes | |
| ENSVATH10734092 | 1256 | Q>K | No | 1000Genomes | |
| ENSVATH06963639 | 1263 | E>A | No | 1000Genomes | |
| tmp_5_4410690_A_T | 1264 | N>K | No | 1000Genomes | |
| ENSVATH00620723 | 1276 | A>G | No | 1000Genomes | |
| tmp_5_4410637_C_A | 1282 | S>I | No | 1000Genomes | |
| tmp_5_4410588_C_A | 1298 | K>N | No | 1000Genomes | |
| ENSVATH00620722 | 1301 | S>T | No | 1000Genomes | |
| tmp_5_4410560_C_A | 1308 | A>S | No | 1000Genomes |
No associated diseases with Q9FNA4
No regional properties for Q9FNA4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9FNA4 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| elongator holoenzyme complex | A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein self-association | Binding to a domain within the same polypeptide. |
| tRNA binding | Binding to a transfer RNA. |
17 GO annotations of biological process
| Name | Definition |
|---|---|
| 5-carbamoylmethyl uridine residue modification | The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA. |
| abscisic acid-activated signaling pathway | The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription. |
| auxin-activated signaling pathway | The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| cellular response to abscisic acid stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. |
| fruit morphogenesis | The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant. |
| leaf morphogenesis | The process in which the anatomical structures of the leaf are generated and organized. |
| negative regulation of anthocyanin metabolic process | Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins. |
| organ growth | The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. |
| positive regulation of cell population proliferation | Any process that activates or increases the rate or extent of cell proliferation. |
| regulation of abscisic acid-activated signaling pathway | Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling. |
| regulation of auxin mediated signaling pathway | Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. |
| regulation of leaf development | Any process that modulates the frequency, rate or extent of leaf development. |
| response to abscisic acid | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. |
| response to oxidative stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. |
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
| tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation | The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKNLKLFSEV | PQNIQLHSTE | EVVQFAAYDI | DQSRLFFASS | ANFVYALQLS | SFQNESAGAK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SAMPVEVCSI | DIEPGDFITA | FDYLAEKESL | LIGTSHGLLL | VHNVESDVTE | LVGNIEGGVK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CISPNPTGDL | LGLITGLGQL | LVMTYDWALM | YEKALGEVPE | GGYVRETNDL | SVNCGGISIS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WRGDGKYFAT | MGEVYESGCM | SKKIKIWESD | SGALQSSSET | KEFTQGILEW | MPSGAKIAAV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YKRKSDDSSP | SIAFFERNGL | ERSSFRIGEP | EDATESCENL | KWNSASDLLA | GVVSCKTYDA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IRVWFFSNNH | WYLKQEIRYP | REAGVTVMWD | PTKPLQLICW | TLSGQVSVRH | FMWVTAVMED |
| 370 | 380 | 390 | 400 | 410 | 420 |
| STAFVIDNSK | ILVTPLSLSL | MPPPMYLFSL | SFSSAVRDIA | YYSRNSKNCL | AVFLSDGNLS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FVEFPAPNTW | EDLEGKDFSV | EISDCKTALG | SFVHLLWLDV | HSLLCVSAYG | SSHNKCLSSG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GYDTELHGSY | LQEVEVVCHE | DHVPDQVTCS | GFKASITFQT | LLESPVLALA | WNPSKRDSAF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VEFEGGKVLG | YASRSEIMET | RSSDDSVCFP | STCPWVRVAQ | VDASGVHKPL | ICGLDDMGRL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SINGKNLCNN | CSSFSFYSEL | ANEVVTHLII | LTKQDFLFIV | DTKDVLNGDV | ALGNVFFVID |
| 670 | 680 | 690 | 700 | 710 | 720 |
| GRRRDEENMS | YVNIWERGAK | VIGVLNGDEA | AVILQTMRGN | LECIYPRKLV | LSSITNALAQ |
| 730 | 740 | 750 | 760 | 770 | 780 |
| QRFKDAFNLV | RRHRIDFNVI | VDLYGWQAFL | QSAVAFVEQV | NNLNHVTEFV | CAMKNEDVTE |
| 790 | 800 | 810 | 820 | 830 | 840 |
| TLYKKFSFSK | KGDEVFRVKD | SCSNKVSSVL | QAIRKALEEH | IPESPSRELC | ILTTLARSDP |
| 850 | 860 | 870 | 880 | 890 | 900 |
| PAIEESLLRI | KSVREMELLN | SSDDIRKKSC | PSAEEALKHL | LWLLDSEAVF | EAALGLYDLN |
| 910 | 920 | 930 | 940 | 950 | 960 |
| LAAIVALNSQ | RDPKEFLPYL | QELEKMPESL | MHFKIDIKLQ | RFDSALRNIV | SAGVGYFPDC |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| MNLIKKNPQL | FPLGLLLITD | PEKKLVVLEA | WADHLIDEKR | FEDAATTYLC | CCKLEKASKA |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| YRECGDWSGV | LRVGALMKLG | KDEILKLAYE | LCEEVNALGK | PAEAAKIALE | YCSDISGGIS |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| LLINAREWEE | ALRVAFLHTA | DDRISVVKSS | ALECASGLVS | EFKESIEKVG | KYLTRYLAVR |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| QRRLLLAAKL | KSEERSVVDL | DDDTASEASS | NLSGMSAYTL | GTRRGSAASV | SSSNATSRAR |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| DLRRQRKSGK | IRAGSAGEEM | ALVDHLKGMR | MTDGGKRELK | SLLICLVTLG | EMESAQKLQQ |
| 1270 | 1280 | 1290 | 1300 | 1310 | |
| TAENFQVSQV | AAVELAHDTV | SSESVDEEVY | CFERYAQKTR | STARDSDAFS | WMLKVFISP |