Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FKH1

Entry ID Method Resolution Chain Position Source
AF-Q9FKH1-F1 Predicted AlphaFoldDB

52 variants for Q9FKH1

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH14519051 10 N>D No 1000Genomes
tmp_5_13940756_C_T 11 G>R No 1000Genomes
tmp_5_13940752_G_A 12 A>V No 1000Genomes
tmp_5_13940743_C_G 15 S>T No 1000Genomes
tmp_5_13940734_A_C 18 V>G No 1000Genomes
ENSVATH11965907 45 V>I No 1000Genomes
tmp_5_13940621_C_T 56 G>S No 1000Genomes
tmp_5_13940618_G_A 57 L>F No 1000Genomes
ENSVATH11965906 60 A>T No 1000Genomes
ENSVATH14519049 65 A>T No 1000Genomes
ENSVATH03245001 75 H>L No 1000Genomes
ENSVATH00674986 75 H>Q No 1000Genomes
ENSVATH00674985 93 A>T No 1000Genomes
tmp_5_13937508_A_G 97 L>S No 1000Genomes
tmp_5_13937502_T_C 99 H>R No 1000Genomes
ENSVATH07216891 104 D>N No 1000Genomes
ENSVATH00674984 118 T>M No 1000Genomes
tmp_5_13937409_G_A 130 P>L No 1000Genomes
ENSVATH07216890 131 S>A No 1000Genomes
tmp_5_13937404_C_A 132 D>Y No 1000Genomes
tmp_5_13937379_G_C 140 S>C No 1000Genomes
tmp_5_13937380_A_T 140 S>T No 1000Genomes
tmp_5_13937212_C_T 196 D>N No 1000Genomes
tmp_5_13937146_G_A 218 H>Y No 1000Genomes
ENSVATH03244996 254 A>T No 1000Genomes
tmp_5_13937017_T_A 261 N>Y No 1000Genomes
tmp_5_13937006_C_G 264 E>D No 1000Genomes
ENSVATH00674983 289 T>M No 1000Genomes
tmp_5_13936930_A_T 290 S>T No 1000Genomes
ENSVATH11965670 296 I>M No 1000Genomes
tmp_5_13936801_T_A 333 I>L No 1000Genomes
ENSVATH07216886 340 N>D No 1000Genomes
ENSVATH03244995 342 E>D No 1000Genomes
tmp_5_13936747_C_G 351 G>R No 1000Genomes
tmp_5_13936743_T_C 352 N>S No 1000Genomes
ENSVATH07216885 355 V>M No 1000Genomes
ENSVATH14519022 360 T>M No 1000Genomes
ENSVATH03244994 361 Q>L No 1000Genomes
tmp_5_13936708_C_G 364 V>L No 1000Genomes
ENSVATH07216882 390 A>V No 1000Genomes
ENSVATH14519021 392 G>S No 1000Genomes
tmp_5_13936621_T_A 393 I>L No 1000Genomes
ENSVATH14519020 394 M>T No 1000Genomes
tmp_5_13936575_A_T 408 I>N No 1000Genomes
ENSVATH03244992 412 V>I No 1000Genomes
ENSVATH07216881 414 E>D No 1000Genomes
ENSVATH07216880 430 A>G No 1000Genomes
tmp_5_13936510_C_T 430 A>T No 1000Genomes
ENSVATH11965667 433 T>M No 1000Genomes
tmp_5_13936498_C_T 434 A>T No 1000Genomes
ENSVATH11965666 435 Q>P No 1000Genomes
tmp_5_13936465_C_A 445 A>S No 1000Genomes

No associated diseases with Q9FKH1

No regional properties for Q9FKH1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FKH1

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

5 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
flower development The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
megasporogenesis The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus.
positive regulation of organ growth Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8CBE3 Wdr37 WD repeat-containing protein 37 Mus musculus (Mouse) PR
Q6NX08 wdr12 Ribosome biogenesis protein wdr12 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MSTSSSSSDN GAGGSGGVFE APSPSRPRRG ANDVWPEPFL ESLAVQVAVN ASTSAGLLAA
70 80 90 100 110 120
APALANVFRV CTTWHAVSRS DHLWQLLSRQ VWARTHLMHD TWRDEFIYRH RTARNFRTRT
130 140 150 160 170 180
HTYFTLQFDP SDVDEPDSLS CRCLTLSDLY LAAGFADGTV RLFLLNNRLH VRTLRPPLRD
190 200 210 220 230 240
RFGRFSRAVS GIVISDSRLT FATMDGDIHV AEIDGVGHTR TAYAGDIVND GALVDFTGCG
250 260 270 280 290 300
RWWVGLFAGV PGRAFHIWDC NSEETTFVGG TLTDPEAVMG WHTLTELTTS LGRLRISGNE
310 320 330 340 350 360
TAVACTRWRI MVIDLRNQGV IIGEDEEQRR GLIVTGFDAN DEAYVRLDSR GNASVRRVNT
370 380 390 400 410 420
QQTVCEFRVS GAAQRRVMGC VNRLHALMCA GGIMRVWEVE RGEYLYSIRE RVGEVDAIVA
430 440
DDRHVAVASA SSTAQSIIHL WDFGAL