Q9ESD6
Gene name |
Cmtm7 (Cklfsf7, Lnv) |
Protein name |
CKLF-like MARVEL transmembrane domain-containing protein 7 |
Names |
Chemokine-like factor superfamily member 7, LNV |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:102545 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ESD6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ESD6-F1 | Predicted | AlphaFoldDB |
13 variants for Q9ESD6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs225423077 | 18 | L>P | No | EVA | |
| rs260736017 | 21 | G>A | No | EVA | |
| rs218368214 | 36 | H>Q | No | EVA | |
| rs3400705579 | 41 | K>N | No | EVA | |
| rs3400700524 | 42 | V>A | No | EVA | |
| rs3389026485 | 42 | V>M | No | EVA | |
| rs3400686198 | 46 | V>G | No | EVA | |
| rs39296874 | 81 | L>F | No | EVA | |
| rs3389076912 | 83 | F>L | No | EVA | |
| rs3389056028 | 84 | Y>* | No | EVA | |
| rs3389090357 | 148 | A>G | No | EVA | |
| rs3412967860 | 153 | S>Y | No | EVA | |
| rs3389074053 | 165 | A>V | No | EVA |
No associated diseases with Q9ESD6
1 regional properties for Q9ESD6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Serine carboxypeptidase, serine active site | 202 - 209 | IPR018202 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cytokine activity | The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| B-1a B cell differentiation | The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors. |
| chemotaxis | The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8IZR5 | CMTM4 | CKLF-like MARVEL transmembrane domain-containing protein 4 | Homo sapiens (Human) | PR |
| Q9DAC0 | Cmtm2b | CKLF-like MARVEL transmembrane domain-containing protein 2B | Mus musculus (Mouse) | PR |
| Q8CJ61 | Cmtm4 | CKLF-like MARVEL transmembrane domain-containing protein 4 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSHGSGLVRT | TCSSGGALGP | GQPSEGLLDR | VYPLTHGALF | KVAQMVTLLI | AFICVRSSVP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IDYGAHSFFE | VVTMCDLIMI | LIFYLVHLFR | FYRVLTCISW | PLSELLHYLI | GTLLLLIASI |
| 130 | 140 | 150 | 160 | ||
| VIASKSYNQS | GLVAGAIFGF | LASFLCLASL | WLSYKITCIT | QSSDASA |