Q9DAC0
Gene name |
Cmtm2b (Cklfsf2b) |
Protein name |
CKLF-like MARVEL transmembrane domain-containing protein 2B |
Names |
Chemokine-like factor superfamily member 2B |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:75502 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9DAC0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9DAC0-F1 | Predicted | AlphaFoldDB |
23 variants for Q9DAC0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs30867401 | 6 | P>Q | No | EVA | |
| rs246077937 | 29 | R>K | No | EVA | |
| rs3388980925 | 33 | K>N | No | EVA | |
| rs219280269 | 51 | L>I | No | EVA | |
| rs234872246 | 59 | Q>E | No | EVA | |
| rs3399637831 | 60 | R>* | No | EVA | |
| rs261419361 | 67 | V>I | No | EVA | |
| rs213539023 | 68 | I>N | No | EVA | |
| rs213539023 | 68 | I>T | No | EVA | |
| rs3388973409 | 115 | G>D | No | EVA | |
| rs3389001939 | 126 | E>* | No | EVA | |
| rs214749707 | 129 | V>M | No | EVA | |
| rs3389007480 | 137 | L>F | No | EVA | |
| rs3388992135 | 142 | A>G | No | EVA | |
| rs3388997654 | 158 | S>T | No | EVA | |
| rs30865128 | 168 | T>A | No | EVA | |
| rs248895443 | 175 | K>M | No | EVA | |
| rs3388992113 | 196 | E>D | No | EVA | |
| rs3388973388 | 198 | A>V | No | EVA | |
| rs254418104 | 201 | A>S | No | EVA | |
| rs225064515 | 205 | S>A | No | EVA | |
| rs244050034 | 207 | D>E | No | EVA | |
| rs214687068 | 208 | P>A | No | EVA |
No associated diseases with Q9DAC0
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cytokine activity | The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| chemotaxis | The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8IZR5 | CMTM4 | CKLF-like MARVEL transmembrane domain-containing protein 4 | Homo sapiens (Human) | PR |
| Q9ESD6 | Cmtm7 | CKLF-like MARVEL transmembrane domain-containing protein 7 | Mus musculus (Mouse) | PR |
| Q8CJ61 | Cmtm4 | CKLF-like MARVEL transmembrane domain-containing protein 4 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAPAPRART | GGKKKDERRG | FKGYKWEFRD | SNKDFWAQGH | AECKSLIMIL | LIAAMVCFQR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VATHPIVILL | LTMELSICAF | FFFLYSLAIN | RYIPFVFWPM | MDLMNDLACS | TFLIGGIFFA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LEARRELPVP | YLTGMILMGV | TAFISIIDLC | LQRRQFKSRK | LRKFILLTPD | RKGKKQDPKL |
| 190 | 200 | ||||
| LLMLAAKEDE | EERQRELAEK | AKRESMDPGW |