Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8CJ61

Entry ID Method Resolution Chain Position Source
AF-Q8CJ61-F1 Predicted AlphaFoldDB

3 variants for Q8CJ61

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389007457 153 A>V No EVA
rs3389010358 166 V>E No EVA
rs3388985059 208 T>A No EVA

No associated diseases with Q8CJ61

No regional properties for Q8CJ61

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8CJ61

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8IZR5 CMTM4 CKLF-like MARVEL transmembrane domain-containing protein 4 Homo sapiens (Human) PR
Q9DAC0 Cmtm2b CKLF-like MARVEL transmembrane domain-containing protein 2B Mus musculus (Mouse) PR
Q9ESD6 Cmtm7 CKLF-like MARVEL transmembrane domain-containing protein 7 Mus musculus (Mouse) PR
10 20 30 40 50 60
MRGGEELDGF EGEASSTSMI SGASSPYQPT TEPVSQRRGL AGLRCDPDYL RGALGRLKVA
70 80 90 100 110 120
QVILALIAFI CIETIMECSP CEGLYFFEFV SCSAFVVTGV LLILFSLNLH MRIPQINWNL
130 140 150 160 170 180
TDLVNTGLST FFFFIASIVL AALNHKTGAE IAAVIFGFLA TAAYAVSTFL AMQKWRVSVR
190 200
QQSTNDYIRA RTESRDVDSR PEIQRLDT