Q9D3V1
Gene name |
Iqcd (Drc10) |
Protein name |
Dynein regulatory complex protein 10 |
Names |
IQ domain-containing protein D |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:75732 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D3V1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D3V1-F1 | Predicted | AlphaFoldDB |
11 variants for Q9D3V1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs235083164 | 14 | G>R | No | EVA | |
| rs32164766 | 17 | I>V | No | EVA | |
| rs3388786638 | 75 | E>G | No | EVA | |
| rs3388786552 | 113 | L>P | No | EVA | |
| rs252597807 | 129 | L>M | No | EVA | |
| rs221624351 | 140 | T>S | No | EVA | |
| rs3388791377 | 186 | E>K | No | EVA | |
| rs3388791368 | 278 | K>M | No | EVA | |
| rs3388782985 | 301 | Q>H | No | EVA | |
| rs230725273 | 307 | M>V | No | EVA | |
| rs215432086 | 444 | A>S | No | EVA |
No associated diseases with Q9D3V1
1 regional properties for Q9D3V1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| binding_site | IQ motif, EF-hand binding site | 396 - 426 | IPR000048 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| ciliary basal body | A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| motile cilium | A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALDQVSIPP | SYHGLAIQRI | PLRTGLVPAE | PMKTLVPSKS | KLNTIEAKRI | MSVLDEAIHK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IELITLMSYM | ESHPEALEDT | LPEDFVRALR | EHLDIGQTLV | ERASILQRRH | KKLEEEEEAE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ETRNQERLLS | LELHKVNLLT | LAHQFRDSTK | TVLRLVLGEP | QFTRLLQVQA | PGRSPGAQCL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LDGLVELRGF | LFEKLLTSPM | EVREKNQFIQ | DISRRSERNQ | EVIDDLQAEL | ANVLKNKESE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VEKENFVIQE | LKNHLHQVFK | FSENSLLRTK | QEAEKQQKVD | FRASQVRLAK | TQQDILALRA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QYHNLVMENR | EAEQALRKKK | YKVETEIENW | IQKYDMEMGE | KQDEYEDLES | IHKEEKLQLE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ELRERHAVLV | EEFSQIRAES | EINSKKRVEA | EREMVRMVRA | ATLIQAVWKG | YLVRSILRSK |
| 430 | 440 | 450 | |||
| KKKRGKGKGK | DKGKGKEKPK | EEKAKEKKPK | AKGKGKKK |