Q5XIR6

PR
Gene name
Iqcd (Drc10)
Protein name
Dynein regulatory complex protein 10
Names
IQ domain-containing protein D
Species
Rattus norvegicus (Rat)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-157 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5XIR6

Entry ID Method Resolution Chain Position Source
AF-Q5XIR6-F1 Predicted AlphaFoldDB

No variants for Q5XIR6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5XIR6

No associated diseases with Q5XIR6

1 regional properties for Q5XIR6

Type Name Position InterPro Accession
binding_site IQ motif, EF-hand binding site 396 - 426 IPR000048

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, flagellum axoneme
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
ciliary basal body A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
motile cilium A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9H095 IQCG Dynein regulatory complex protein 9 Homo sapiens (Human) PR
Q9D3V1 Iqcd Dynein regulatory complex protein 10 Mus musculus (Mouse) PR
Q80W32 Iqcg Dynein regulatory complex protein 9 Mus musculus (Mouse) PR
10 20 30 40 50 60
MALNLLSIPP SYHGLIIQRI PLKTGLVPAE PLKTLAPSKS KLNTIEAKRI MSVLDEAINK
70 80 90 100 110 120
VELITLMSYL ESHPEALEDA LPENFVEAIR EHLDIGQALV EKASILQRKQ KELEKGEEAE
130 140 150 160 170 180
EDWDQERLLS IELHKTNLWP LTHQFRDSTK TILRLLINEP QLTRLLHTQA PGRSPGAQCL
190 200 210 220 230 240
LTSLVELRGF LFEKLLTSPM EVREKNQFIQ DISRRSKRNQ EIIDALQAEL AEVLKNKEAE
250 260 270 280 290 300
VEKENFVIQE LKNHLHQVFK FSENSLLRTK QEAEKQQKVD YRASQARQAK TQQDILALRA
310 320 330 340 350 360
QYHNLVMENR EAEQALRKKK YKVETEIENW IQKYDMEMNE KQEEYEDLET IHKEEKLQLE
370 380 390 400 410 420
ELKERHAVLV EEFSQIRAES EINSKKRVEA EREMVRMVRA ATLIQAMWKG YLVRSMLRSR
430 440 450
KKKRVKSKGK DKGKGKEKPK EEKGKEKKAK GKGKGKK