Q9D1N9
Gene name |
Mrpl21 (D9Wsu149) |
Protein name |
39S ribosomal protein L21, mitochondrial |
Names |
L21mt, MRP-L21 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:353242 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D1N9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D1N9-F1 | Predicted | AlphaFoldDB |
10 variants for Q9D1N9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs37227651 | 26 | L>S | No | EVA | |
| rs3389514363 | 35 | S>P | No | EVA | |
| rs258626561 | 57 | K>E | No | EVA | |
| rs3389506539 | 67 | E>D | No | EVA | |
| rs260608984 | 86 | R>K | No | EVA | |
| rs234699912 | 93 | T>A | No | EVA | |
| rs252293346 | 96 | Y>H | No | EVA | |
| rs3389514217 | 101 | A>T | No | EVA | |
| rs3389513301 | 173 | K>Q | No | EVA | |
| rs3389513365 | 194 | Q>R | No | EVA |
No associated diseases with Q9D1N9
No regional properties for Q9D1N9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9D1N9 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrial large ribosomal subunit | The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial translation | The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAAIAASAL | PGAFGRLVSV | CSRSILASQG | SGSASLWSAS | RRFNSQSASY | PQGYVPKTSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SSPPWQEVVL | PDPVEETRHH | AEVVKRVNEL | IATGQYGRLF | AVVHFASHQW | KVTAEDLILI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ENELDIKCGE | RIRLEKVLLV | GADNFTLLGK | PLLRKELVRV | EATVIEKTES | WPKINMKFRK |
| 190 | 200 | ||||
| RKNFRKKKII | VNPQTILRIN | TIEIAPRLL |