Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9C591

Entry ID Method Resolution Chain Position Source
AF-Q9C591-F1 Predicted AlphaFoldDB

14 variants for Q9C591

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH07008233 7 Y>F No 1000Genomes
tmp_5_7259141_G_T 24 L>I No 1000Genomes
tmp_5_7259128_C_A 28 R>L No 1000Genomes
ENSVATH00636947 34 G>R No 1000Genomes
ENSVATH03090740 64 D>N No 1000Genomes
tmp_5_7258955_G_A 86 R>C No 1000Genomes
ENSVATH07008232 99 H>R No 1000Genomes
ENSVATH07008230 107 D>G No 1000Genomes
ENSVATH07008229 108 H>Q No 1000Genomes
tmp_5_7258885_T_A 109 N>I No 1000Genomes
tmp_5_7258771_G_A 147 T>M No 1000Genomes
ENSVATH10907277 173 F>L No 1000Genomes
tmp_5_7258650_T_G 187 Q>H No 1000Genomes
tmp_5_7258577_T_C 212 N>D No 1000Genomes

No associated diseases with Q9C591

8 regional properties for Q9C591

Type Name Position InterPro Accession
domain FERM domain 43 - 327 IPR000299
domain FERM adjacent 336 - 380 IPR014847
domain FERM, N-terminal 47 - 109 IPR018979
domain FERM, C-terminal PH-like domain 239 - 331 IPR018980
conserved_site FERM conserved site 97 - 126 IPR019747-1
conserved_site FERM conserved site 205 - 234 IPR019747-2
domain FERM central domain 127 - 235 IPR019748
domain Band 4.1 domain 39 - 235 IPR019749

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

1 GO annotations of biological process

Name Definition
ethylene-activated signaling pathway The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9S7L5 ERF018 Ethylene-responsive transcription factor ERF018 Arabidopsis thaliana (Mouse-ear cress) PR
Q39127 TINY Ethylene-responsive transcription factor TINY Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDASPKYTGV RKRKWGKWVA EIRLPNSRDR IWLGSFDSAE KAARAFDAAL YCLRGPGARF
70 80 90 100 110 120
NFPDNPPEIP GGRSLTPQQI QVVASRFACE EELLPPEQHH PSPPRGDHNT EEEVIISARG
130 140 150 160 170 180
EINSGSGGPT LGQVGEDNNN EGNSNDTSSY WPLIWEEENF VGPPNSDHEF GFFTDDSTNL
190 200 210
YFPTQQQQQH QLSSDFYYDG ACEDDFSHYN INLWNF