Q39127

PR
Gene name
TINY (ERF040, At5g25810, F18A17.60)
Protein name
Ethylene-responsive transcription factor TINY
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G25810
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q39127

Entry ID Method Resolution Chain Position Source
AF-Q39127-F1 Predicted AlphaFoldDB

21 variants for Q39127

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_8987614_T_G 7 T>P No 1000Genomes
ENSVATH07045848 10 W>S No 1000Genomes
ENSVATH07045846 14 A>G No 1000Genomes
ENSVATH07045847 14 A>S No 1000Genomes
ENSVATH07045847 14 A>T No 1000Genomes
ENSVATH07045845 19 N>S No 1000Genomes
ENSVATH15687791 20 E>K No 1000Genomes
tmp_5_8987530_C_T 35 V>I No 1000Genomes
ENSVATH14199567 39 V>I No 1000Genomes
ENSVATH07045843 55 R>K No 1000Genomes
tmp_5_8987460_G_T 58 S>Y No 1000Genomes
tmp_5_8987380_C_T 85 A>T No 1000Genomes
ENSVATH11057748 88 I>T No 1000Genomes
tmp_5_8987371_T_C 88 I>V No 1000Genomes
tmp_5_8987323_G_C 104 L>V No 1000Genomes
ENSVATH11057746 125 F>S No 1000Genomes
ENSVATH11057704 150 A>V No 1000Genomes
tmp_5_8987151_T_G 161 E>A No 1000Genomes
ENSVATH07045841 169 Y>D No 1000Genomes
tmp_5_8987107_C_A 176 G>C No 1000Genomes
ENSVATH11057702 192 P>L No 1000Genomes

No associated diseases with Q39127

5 regional properties for Q39127

Type Name Position InterPro Accession
domain IPT domain 255 - 339 IPR002909
conserved_site Transcription factor COE, conserved site 162 - 171 IPR018350
domain Transcription factor COE, DNA-binding domain 22 - 248 IPR032200
domain Transcription factor COE, helix-loop-helix domain 341 - 384 IPR032201
domain Transcription factor COE, IPT domain 256 - 340 IPR038006

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9S7L5 ERF018 Ethylene-responsive transcription factor ERF018 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C591 ERF016 Ethylene-responsive transcription factor ERF016 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MIASESTKSW EASAVRQENE EEKKKPVKDS GKHPVYRGVR KRNWGKWVSE IREPRKKSRI
70 80 90 100 110 120
WLGTFPSPEM AARAHDVAAL SIKGASAILN FPDLAGSFPR PSSLSPRDIQ VAALKAAHME
130 140 150 160 170 180
TSQSFSSSSS LTFSSSQSSS SLESLVSSSA TGSEELGEIV ELPSLGSSYD GLTQLGNEFI
190 200 210
FSDSADLWPY PPQWSEGDYQ MIPASLSQDW DLQGLYNY