Q99KK1
Gene name |
Reep3 (D10Ucla1) |
Protein name |
Receptor expression-enhancing protein 3 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:28193 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q99KK1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q99KK1-F1 | Predicted | AlphaFoldDB |
9 variants for Q99KK1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs47148584 | 18 | Y>S | No | EVA | |
| rs3412481361 | 43 | I>N | No | EVA | |
| rs3389083038 | 49 | T>N | No | EVA | |
| rs3389109736 | 50 | V>I | No | EVA | |
| rs3389114709 | 87 | I>N | No | EVA | |
| rs3389102346 | 88 | Y>H | No | EVA | |
| rs3389103503 | 170 | Y>D | No | EVA | |
| rs212909928 | 178 | R>K | No | EVA | |
| rs217339747 | 218 | A>V | No | EVA |
No associated diseases with Q99KK1
No regional properties for Q99KK1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q99KK1 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic microtubule | Any microtubule in the cytoplasm of a cell. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| endoplasmic reticulum tubular network | A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| endoplasmic reticulum tubular network organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section. |
| mitotic nuclear membrane reassembly | The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge. |
| nuclear envelope organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVSWMISRAV | VLVFGMLYPA | YYSYKAVKTK | NVKEYVRWMM | YWIVFALYTV | IETVADQTLA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WFPLYYELKI | AFVIWLLSPY | TRGASLIYRK | FLHPLLSSKE | REIDDYIVQA | KERGYETMVN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FGRQGLNLAA | AAAVTAAVKS | QGAITERLRS | FSMHDLTAIQ | GDEPVGHRPY | QTLPEAKRKG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KQATESPAYG | IPLKDGSEQT | DEEAEGPFSD | DEMVTHKALR | RSQSMKSVKT | IKGRKEVRYG |
| 250 | |||||
| SLKYKVKKRP | QVYF |