Q8LEM6

PR
Gene name
HVA22H (At1g19950, T20H2.26)
Protein name
HVA22-like protein h
Names
AtHVA22h
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G19950
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

118-315 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8LEM6

Entry ID Method Resolution Chain Position Source
AF-Q8LEM6-F1 Predicted AlphaFoldDB

15 variants for Q8LEM6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00032933 26 A>V No 1000Genomes
ENSVATH11582948 30 N>K No 1000Genomes
ENSVATH11582952 120 A>V No 1000Genomes
tmp_1_6925805_G_C 128 V>L No 1000Genomes
tmp_1_6926076_A_T 166 Q>L No 1000Genomes
tmp_1_6926085_C_T 169 P>L No 1000Genomes
tmp_1_6926112_C_T 178 A>V No 1000Genomes
tmp_1_6926187_C_A 203 P>H No 1000Genomes
ENSVATH11582953 220 A>V No 1000Genomes
tmp_1_6926334_C_A 252 A>E No 1000Genomes
ENSVATH11583015 281 S>F No 1000Genomes
ENSVATH13929455 294 M>I No 1000Genomes
ENSVATH11583016 302 R>H No 1000Genomes
tmp_1_6926511_C_T 311 A>V No 1000Genomes
ENSVATH11583017 315 R>L No 1000Genomes

No associated diseases with Q8LEM6

No regional properties for Q8LEM6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8LEM6

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6NUK4 REEP3 Receptor expression-enhancing protein 3 Homo sapiens (Human) PR
Q99KK1 Reep3 Receptor expression-enhancing protein 3 Mus musculus (Mouse) PR
Q9LR09 HVA22G Putative HVA22-like protein g Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MIGSFLTRGL VMVFGYAYPA YECYKAVEKN KPEMQQLRFW CQYWILVAAL TIFERVGDAL
70 80 90 100 110 120
ASWVPLYCEA KLAFFIYLWF PKTRGTTYVY DSFFQPYVAK HENEIDRSLI ELRTKAGDLA
130 140 150 160 170 180
VIYCRKAVSY GQTRIVEILH FVALQSTPKP KPKEKKQAAA PEEEEQKQPD LKATSQAASS
190 200 210 220 230 240
NPQVRLQSKK PQLVTKEPIS PKPLSSPRKQ QQLQTETKEA KASVSQTKLT TLTPPGPPPP
250 260 270 280 290 300
PPPPPPSPTT AAKRNADPAQ PSPTEAEEAS QTVAALPEPA SEIQRASSSK ETIMEETLRI
310
TRGSLRKARS AGAPR