Q96FV2
PR
Gene name |
SCRN2 |
Protein name |
Secernin-2 |
Names |
|
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:90507 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q96FV2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q96FV2-F1 | Predicted | AlphaFoldDB |
409 variants for Q96FV2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs138512728 CA8628421 |
2 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1598053131 CA400094774 |
3 | S>A | No |
ClinGen Ensembl |
|
|
rs1448557007 CA400094769 |
3 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA291306676 rs974162394 |
4 | S>L | No |
ClinGen Ensembl |
|
|
rs1320986751 CA400094738 |
6 | P>S | No |
ClinGen gnomAD |
|
|
CA400094700 rs1219372546 |
8 | S>F | No |
ClinGen gnomAD |
|
|
CA8628416 rs745534015 |
9 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA400094691 rs1383203588 |
9 | P>L | No |
ClinGen TOPMed |
|
|
CA8628414 rs780977396 |
10 | C>R | No |
ClinGen ExAC gnomAD |
|
|
rs1298414621 CA400094671 |
11 | S>A | No |
ClinGen TOPMed |
|
|
CA291306653 rs908574404 |
12 | C>R | No |
ClinGen gnomAD |
|
|
rs1306080350 CA400094660 |
12 | C>Y | No |
ClinGen TOPMed |
|
|
rs1404194537 CA400094649 |
13 | D>G | No |
ClinGen gnomAD |
|
|
CA400094638 rs1274244531 |
14 | C>R | No |
ClinGen TOPMed |
|
|
rs986796006 CA291306650 |
14 | C>S | No |
ClinGen Ensembl |
|
|
rs1166187347 CA400094590 |
18 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs758439321 CA8628410 |
19 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA291306647 rs1018474256 |
20 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1182755512 CA400094571 |
20 | P>S | No |
ClinGen gnomAD |
|
|
CA8628407 rs765416800 |
21 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA8628406 rs759761867 |
24 | I>F | No |
ClinGen ExAC gnomAD |
|
|
rs1306456209 CA400094529 |
24 | I>T | No |
ClinGen gnomAD |
|
|
CA400094514 rs1270314900 |
25 | P>L | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 26 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA400094475 rs1215767046 |
28 | I>T | No |
ClinGen gnomAD |
|
|
CA400094455 rs1344956172 |
29 | F>L | No |
ClinGen gnomAD |
|
|
rs200222425 CA8628405 |
30 | A>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1298903827 CA400094453 |
30 | A>T | No |
ClinGen gnomAD |
|
|
rs773736281 CA8628402 |
32 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628401 rs772529577 |
33 | S>L | No |
ClinGen ExAC gnomAD |
|
|
CA400094392 rs772529577 |
33 | S>W | No |
ClinGen ExAC gnomAD |
|
|
rs774925208 CA8628399 |
35 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA400094306 rs1390781060 |
39 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
CA400094301 rs1419845169 |
40 | V>G | No |
ClinGen TOPMed |
|
|
CA8628398 rs769298386 |
40 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1163640568 CA400094261 |
43 | V>E | No |
ClinGen TOPMed |
|
|
rs1163640568 CA400094256 |
43 | V>G | No |
ClinGen TOPMed |
|
|
rs371944909 CA8628397 |
43 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8628396 rs780770132 |
44 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA8628395 rs770740608 |
45 | F>I | No |
ClinGen ExAC gnomAD |
|
|
rs1480120446 CA400094196 |
47 | P>L | No |
ClinGen gnomAD |
|
|
CA400094185 rs1230763685 |
48 | A>G | No |
ClinGen TOPMed gnomAD |
|
|
CA291306594 rs11556380 |
48 | A>T | No |
ClinGen Ensembl |
|
|
rs1449121975 CA400094160 |
50 | T>I | No |
ClinGen gnomAD |
|
|
rs746822156 CA8628394 |
53 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA8628393 rs141077668 |
54 | G>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA400094054 rs1357867308 |
57 | L>I | No |
ClinGen TOPMed gnomAD |
|
|
rs770438007 CA8628378 |
59 | C>G | No |
ClinGen ExAC gnomAD |
|
|
CA8628376 rs200136043 |
62 | I>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA400093892 rs1598052491 |
63 | E>G | No |
ClinGen Ensembl |
|
|
CA400093884 rs1342782500 |
64 | V>M | No |
ClinGen TOPMed |
|
|
rs141690344 CA8628374 |
68 | S>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs141690344 CA8628373 |
68 | S>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 70 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA400093779 rs371057387 |
70 | T>K | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs371057387 CA291306364 |
70 | T>M | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA400093774 rs780206566 |
71 | H>N | No |
ClinGen ExAC gnomAD |
|
|
rs1428085984 CA400093765 |
71 | H>Q | No |
ClinGen gnomAD |
|
|
CA8628370 rs780206566 |
71 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1468679744 CA400093723 |
74 | I>L | No |
ClinGen TOPMed |
|
|
CA400093715 rs1270181397 |
74 | I>T | No |
ClinGen gnomAD |
|
|
rs1192252653 CA400093702 |
75 | L>R | No |
ClinGen gnomAD |
|
|
CA400093689 rs1194924586 |
76 | S>N | No |
ClinGen TOPMed |
|
|
rs144648187 CA8628364 |
77 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA8628363 rs539260343 |
77 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA400093665 rs765916305 |
78 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1221822738 CA400093658 |
78 | P>L | No |
ClinGen gnomAD |
|
|
CA8628361 rs765916305 |
78 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628362 rs765916305 |
78 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628360 rs760236168 |
79 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs771969789 CA8628358 |
80 | W>C | No |
ClinGen ExAC gnomAD |
|
|
CA400093597 rs774317779 |
82 | W>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA400093591 rs1399798572 |
82 | W>C | No |
ClinGen TOPMed |
|
|
CA8628356 rs774317779 |
82 | W>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779932085 CA8628353 |
84 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1020664148 CA291306325 |
85 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
rs756285524 CA8628352 |
86 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA400093541 rs1169931769 |
86 | M>V | No |
ClinGen Ensembl |
|
|
CA8628350 rs781445482 |
88 | A>T | No |
ClinGen ExAC |
|
|
rs1363748507 CA400093498 |
88 | A>V | No |
ClinGen TOPMed |
|
|
rs751884781 CA8628349 |
89 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764452134 CA8628347 |
90 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA8628346 rs529039186 |
93 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA400093390 rs1598052220 |
95 | I>L | No |
ClinGen Ensembl |
|
|
CA400093383 rs753309612 |
95 | I>N | No |
ClinGen ExAC gnomAD |
|
|
CA8628345 rs753309612 |
95 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA291306295 rs374764950 |
97 | N>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1025263280 CA291306292 |
101 | W>G | No |
ClinGen Ensembl |
|
|
rs145155073 CA8628342 |
102 | T>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1198729199 CA400093251 |
103 | K>E | No |
ClinGen TOPMed |
|
|
rs17856536 VAR_029509 CA8628340 |
103 | K>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs111736975 CA8628339 |
106 | V>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1215807428 CA400093194 |
107 | G>R | No |
ClinGen gnomAD |
|
| rs1191951193 | 110 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1381732789 CA400093121 |
111 | A>V | No |
ClinGen gnomAD |
|
|
rs377578539 CA8628336 |
114 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1199712522 CA400093069 |
115 | M>I | No |
ClinGen Ensembl |
|
|
CA400093072 rs1297110059 |
115 | M>R | No |
ClinGen gnomAD |
|
|
rs373523091 CA8628335 |
118 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs372508790 CA8628307 |
121 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs138415129 CA8628306 |
123 | E>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs138415129 CA400092861 |
123 | E>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8628304 rs552628767 |
124 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA8628305 rs201366477 |
124 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8628303 rs755484212 |
126 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1452013948 CA400092726 |
130 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
CA400092671 rs1206541489 |
133 | H>Q | No |
ClinGen gnomAD |
|
|
CA8628297 rs758020488 |
135 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs752492059 CA8628296 |
136 | T>A | No |
ClinGen ExAC |
|
|
rs1477260134 CA400092589 |
138 | L>F | No |
ClinGen TOPMed |
|
|
rs759461917 CA8628294 |
143 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA291303942 rs938811075 |
144 | Q>R | No |
ClinGen TOPMed gnomAD |
|
|
CA400092144 rs1598051398 |
145 | G>E | No |
ClinGen Ensembl |
|
|
CA8628292 CA400092147 COSM1479686 rs766421033 |
145 | G>R | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD NCI-TCGA |
|
rs772286172 CA8628289 |
146 | G>A | No |
ClinGen ExAC gnomAD |
|
| rs750983392 | 146 | G>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs773195495 CA8628290 |
146 | G>C | No |
ClinGen ExAC gnomAD |
|
|
rs773195495 CA400092142 |
146 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA400092125 rs1160173387 |
148 | C>F | No |
ClinGen gnomAD |
|
|
rs1469389758 CA400092116 |
149 | L>P | No |
ClinGen gnomAD |
|
|
rs1174338659 CA400092110 |
150 | E>Q | No |
ClinGen gnomAD |
|
|
rs200085997 CA8628286 |
153 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1386006181 CA400092067 |
154 | P>L | No |
ClinGen gnomAD |
|
|
CA8628284 rs749802427 |
156 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA291303907 rs376550553 |
157 | Y>H | No |
ClinGen Ensembl |
|
|
CA8628283 rs371394444 |
158 | H>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs368823871 CA8628282 |
159 | S>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1280169048 CA400092001 |
160 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1280169048 CA400092002 |
160 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1219238222 CA400091979 |
163 | L>M | No |
ClinGen gnomAD |
|
|
rs562524135 CA8628281 |
163 | L>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8628280 rs139229069 |
164 | A>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA400091971 rs139229069 |
164 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs201868822 CA8628278 |
166 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA400091947 rs201868822 |
166 | R>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs146219626 CA291303858 COSM980544 |
166 | R>H | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA8628277 rs146219626 |
166 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA400091942 rs1598051234 |
167 | T>P | No |
ClinGen Ensembl |
|
|
CA8628276 rs754814036 |
167 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA400091926 rs1336247522 |
168 | E>D | No |
ClinGen gnomAD |
|
|
CA400091918 rs1369950760 |
169 | A>G | No |
ClinGen TOPMed gnomAD |
|
|
CA400091923 rs1415101295 |
169 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA400091916 rs1369950760 |
169 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1300620311 CA400091902 |
171 | V>M | No |
ClinGen TOPMed |
|
|
rs1358967638 CA400091858 |
175 | A>S | No |
ClinGen TOPMed |
|
|
rs1475401976 CA400091807 |
179 | W>C | No |
ClinGen Ensembl |
|
| TCGA novel | 180 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8628271 rs199533557 |
182 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628272 rs199533557 |
182 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762090788 CA8628270 |
183 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA400091763 rs1567956680 |
184 | I>V | No |
ClinGen Ensembl |
|
| TCGA novel | 185 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA400091735 rs141595908 |
186 | E>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs141595908 CA8628269 |
186 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA400091669 rs1350061315 |
187 | G>W | No |
ClinGen gnomAD |
|
|
rs1411675593 CA400091662 |
188 | A>T | No |
ClinGen gnomAD |
|
|
rs544440097 CA291303424 |
188 | A>V | No |
ClinGen 1000Genomes gnomAD |
|
|
CA8628253 rs761850321 |
189 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751802544 COSM472940 CA8628252 |
189 | R>H | kidney Variant assessed as Somatic; 0.0 impact. large_intestine [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA400091617 rs1456404635 |
192 | S>A | No |
ClinGen gnomAD |
|
|
rs764374756 CA8628251 |
192 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs1160755914 CA400091597 |
193 | N>K | No |
ClinGen gnomAD |
|
|
CA400091580 rs1472623764 |
195 | L>Q | No |
ClinGen gnomAD |
|
|
rs775943349 CA400091560 |
197 | I>L | No |
ClinGen ExAC gnomAD |
|
|
CA8628248 rs770061842 |
197 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs775943349 CA8628249 |
197 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA8628247 rs760071512 |
198 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs143848838 CA8628246 |
199 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs149653266 CA400091457 |
202 | S>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs149653266 CA8628244 |
202 | S>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs866173364 CA291303373 |
204 | Q>* | No |
ClinGen Ensembl |
|
|
CA291303368 rs866580917 |
205 | H>Q | No |
ClinGen gnomAD |
|
|
rs138323768 CA8628242 |
206 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs778415546 CA8628243 |
206 | P>S | No |
ClinGen ExAC TOPMed |
|
|
rs779818477 CA8628239 |
207 | E>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628237 rs201722687 |
209 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755921644 CA8628238 |
209 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs909604689 CA291303320 |
210 | T>I | No |
ClinGen gnomAD |
|
|
CA400091307 rs376210020 |
211 | H>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs376210020 CA8628236 |
211 | H>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8628235 rs757251902 |
212 | A>G | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs751643426 CA8628234 |
213 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs200507127 CA8628233 |
216 | G>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8628232 rs763205655 |
217 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs763205655 CA400091214 |
217 | W>C | No |
ClinGen ExAC gnomAD |
|
|
rs572745262 CA291303303 |
217 | W>R | No |
ClinGen 1000Genomes |
|
|
rs753038876 CA400091204 |
218 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs753038876 CA8628231 |
218 | W>L | No |
ClinGen ExAC gnomAD |
|
|
rs1427799614 CA400091182 |
219 | D>N | No |
ClinGen gnomAD |
|
|
rs570410687 CA291303275 |
220 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA400091117 rs1210796579 |
222 | G>D | No |
ClinGen gnomAD |
|
|
CA400091125 rs1246463825 |
222 | G>S | No |
ClinGen gnomAD |
|
|
rs769196425 CA291303267 |
228 | Q>P | No |
ClinGen gnomAD |
|
|
CA400090980 rs1301875620 |
229 | I>N | No |
ClinGen gnomAD |
|
|
CA8628226 rs771290354 |
229 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1598050170 CA400090893 |
233 | T>P | No |
ClinGen Ensembl |
|
|
rs370974672 CA8628221 |
236 | P>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA400090826 rs1159384673 |
236 | P>L | No |
ClinGen TOPMed |
|
|
CA400090818 rs1300583508 |
237 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA8628220 rs749702891 |
238 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA8628219 rs141728182 |
238 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs757086961 CA8628217 |
239 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs1331814914 CA400090699 |
243 | K>E | No |
ClinGen TOPMed |
|
|
rs375757690 CA8628215 |
245 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs375757690 CA8628216 |
245 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8628214 rs139216151 |
245 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
CA8628212 rs765334493 |
247 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA400090615 rs1598050065 |
247 | Q>R | No |
ClinGen Ensembl |
|
|
rs1484272754 CA400090588 |
248 | A>V | No |
ClinGen gnomAD |
|
|
rs372666717 CA8628210 |
250 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs766769648 CA8628209 |
250 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs372666717 COSM1224970 CA8628211 |
250 | R>W | large_intestine [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs1598050035 CA400090563 |
251 | E>G | No |
ClinGen Ensembl |
|
|
CA8628207 rs773765468 |
254 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs140113065 CA8628208 |
254 | R>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8628205 rs199783567 |
256 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA400090498 rs769284762 |
256 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628203 rs769284762 |
256 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs199783567 CA8628204 |
256 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA400090408 rs1418779395 |
258 | G>E | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 259 | G>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA400090387 rs1471648935 |
259 | G>D | No |
ClinGen gnomAD |
|
|
CA8628186 rs764811245 |
261 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA400090317 rs1450913002 |
262 | A>G | No |
ClinGen gnomAD |
|
| TCGA novel | 263 | E>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1598049754 CA400090272 |
264 | V>G | No |
ClinGen Ensembl |
|
|
rs776407344 CA8628184 |
264 | V>L | No |
ClinGen ExAC gnomAD |
|
|
rs770814864 CA8628183 |
265 | M>T | No |
ClinGen ExAC |
|
|
CA291303083 rs993783702 |
267 | G>S | No |
ClinGen TOPMed |
|
|
CA8628181 rs773160472 |
272 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
CA400090074 rs35901087 |
273 | E>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
VAR_035263 CA8628180 rs35901087 |
273 | E>Q | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA400090003 rs1357400347 |
274 | S>N | No |
ClinGen gnomAD |
|
|
CA400089982 rs1311240282 |
275 | G>D | No |
ClinGen gnomAD |
|
|
rs201186794 CA8628178 |
275 | G>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8628177 rs201186794 |
275 | G>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA291303030 rs976423790 |
277 | C>R | No |
ClinGen Ensembl |
|
|
CA400089937 rs1456528317 |
278 | M>T | No |
ClinGen TOPMed |
|
| TCGA novel | 278 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA291303024 rs576520865 |
280 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs868843160 CA291303002 |
281 | G>* | No |
ClinGen gnomAD |
|
|
rs868843160 CA400089861 |
281 | G>R | No |
ClinGen gnomAD |
|
|
rs1567955964 CA400089831 |
282 | G>V | No |
ClinGen Ensembl |
|
|
rs142383711 CA8628174 |
284 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs142383711 CA400089787 |
284 | R>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA291302996 rs911443107 |
284 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs199517110 CA291302994 |
285 | T>A | No |
ClinGen 1000Genomes |
|
|
CA400089756 rs1428350205 |
285 | T>I | No |
ClinGen TOPMed |
|
|
rs943646795 CA291302991 |
286 | T>A | No |
ClinGen TOPMed |
|
|
rs190097354 CA8628173 |
286 | T>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1414311832 CA400089708 |
288 | S>N | No |
ClinGen gnomAD |
|
|
CA291302963 rs978928904 |
289 | M>V | No |
ClinGen Ensembl |
|
|
rs757696646 CA8628171 |
291 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA400089645 rs1477658910 |
292 | V>L | No |
ClinGen gnomAD |
|
|
CA8628170 rs546999372 |
295 | Q>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA400089549 rs1293651014 |
298 | T>A | No |
ClinGen TOPMed |
|
|
CA8628169 rs7350956 |
298 | T>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs7350956 CA400089530 |
298 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA291302937 rs7350956 |
298 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628167 rs564586578 |
299 | Q>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA400089511 rs1247071375 |
299 | Q>R | No |
ClinGen gnomAD |
|
|
rs1465945576 CA400089487 |
300 | P>L | No |
ClinGen gnomAD |
|
|
CA291302934 rs960132230 |
301 | C>R | No |
ClinGen TOPMed |
|
|
CA8628165 rs552325337 |
302 | V>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8628164 rs552325337 |
302 | V>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs530726051 CA8628163 |
303 | H>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA8628162 rs530726051 |
303 | H>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1226778714 CA400089389 |
305 | L>P | No |
ClinGen TOPMed |
|
|
rs755649777 CA291302913 |
305 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
rs372886856 CA8628159 |
307 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8628158 rs368479709 |
308 | T>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1413964084 CA400089332 |
309 | P>A | No |
ClinGen gnomAD |
|
|
CA8628156 rs746097359 |
309 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1420985972 CA400089260 COSM1679885 |
312 | S>F | large_intestine [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
COSM1679885 CA291302866 rs868052169 |
312 | S>F | large_intestine [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
rs745395019 CA291302863 |
313 | R>K | No |
ClinGen Ensembl |
|
|
CA400089138 rs1338750692 |
315 | V>A | No |
ClinGen gnomAD |
|
|
CA400089109 rs1314771392 |
317 | K>T | No |
ClinGen gnomAD |
|
|
CA400089056 rs1369815612 |
320 | I>V | No |
ClinGen gnomAD |
|
|
rs924494537 CA291302797 |
321 | F>C | No |
ClinGen TOPMed |
|
|
CA8628145 rs761707106 |
322 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA291302780 rs761707106 |
322 | G>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376597524 CA8628143 |
323 | M>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs7350974 CA400089024 CA400089019 |
323 | M>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs7350974 VAR_029510 CA8628144 |
323 | M>V | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA400088997 rs1187963697 |
324 | G>E | No |
ClinGen gnomAD |
|
|
CA400089004 rs1238735438 |
324 | G>R | No |
ClinGen gnomAD |
|
|
rs1486291837 CA400088990 |
325 | V>L | No |
ClinGen gnomAD |
|
|
CA8628139 rs769930573 |
329 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA400088904 rs1274032943 |
330 | Q>E | No |
ClinGen gnomAD |
|
|
VAR_035264 CA8628137 rs34480825 |
330 | Q>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP |
|
|
rs1555634924 CA8628135 |
331 | V>E | No |
ClinGen Ensembl |
|
|
rs776892060 CA8628134 |
332 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA8628132 rs747346545 |
333 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA400088839 rs1421568428 |
334 | P>A | No |
ClinGen TOPMed |
|
|
rs1306078512 CA400088814 |
335 | T>I | No |
ClinGen gnomAD |
|
|
CA400088826 rs1385152007 |
335 | T>P | No |
ClinGen TOPMed |
|
|
CA8628130 rs758870326 |
338 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA400088767 rs1420896572 |
338 | A>V | No |
ClinGen TOPMed |
|
|
CA400088765 rs1163760830 |
339 | Q>* | No |
ClinGen gnomAD |
|
|
CA8628129 rs576491867 |
339 | Q>P | No |
ClinGen 1000Genomes ExAC |
|
|
CA8628128 rs779696133 |
340 | D>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA |
|
rs199980564 CA8628127 |
341 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA400088701 rs145068403 |
343 | R>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8628124 rs145068403 |
343 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs767158187 CA8628125 |
343 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA400088695 rs1567955539 |
344 | T>A | No |
ClinGen Ensembl |
|
|
rs1481876550 CA400088668 |
345 | L>M | No |
ClinGen gnomAD |
|
|
rs751312413 CA8628123 |
347 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751312413 CA400088645 |
347 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs144133774 CA8628122 |
347 | R>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8628121 COSM980542 rs144133774 |
347 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA400088630 rs1275281211 |
348 | F>V | No |
ClinGen gnomAD |
|
|
rs1328548045 CA400088608 |
349 | Q>* | No |
ClinGen gnomAD |
|
|
rs1598048778 CA400088597 |
349 | Q>P | No |
ClinGen Ensembl |
|
|
rs1314542505 CA400088581 |
350 | T>A | No |
ClinGen TOPMed |
|
|
rs569100056 CA291302700 |
350 | T>I | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA400088574 rs569100056 |
350 | T>N | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA400088565 rs1567955501 |
351 | Q>* | No |
ClinGen Ensembl |
|
|
rs1225425200 CA400088554 CA400088550 |
351 | Q>H | No |
ClinGen gnomAD |
|
|
CA400088561 rs1286480896 |
351 | Q>R | No |
ClinGen gnomAD |
|
|
CA291302689 rs867357293 |
352 | V>A | No |
ClinGen Ensembl |
|
|
CA8628119 rs775467440 |
354 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA8628118 COSM2697022 rs765282643 |
354 | R>H | Variant assessed as Somatic; 0.0 impact. pancreas [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA8628116 rs776709838 |
355 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759656311 CA8628117 |
355 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1482108851 CA400088448 |
356 | H>R | No |
ClinGen TOPMed |
|
|
CA400088427 rs1182428346 |
357 | T>I | No |
ClinGen TOPMed |
|
|
CA400088438 rs1456291066 |
357 | T>P | No |
ClinGen gnomAD |
|
|
rs771123017 CA8628115 |
358 | L>P | No |
ClinGen ExAC |
|
|
CA8628114 rs747197925 |
359 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs561508132 CA8628113 |
360 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs561508132 CA400088388 |
360 | R>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
COSM1383959 rs374214556 CA8628112 |
360 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed |
|
CA8628111 rs374214556 |
360 | R>P | No |
ClinGen ESP ExAC TOPMed |
|
| TCGA novel | 363 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA400088333 rs1421401539 |
364 | A>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1421401539 CA400088331 |
364 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1191050120 CA400088311 |
366 | L>V | No |
ClinGen gnomAD |
|
|
CA8628106 rs756875270 |
367 | G>E | No |
ClinGen ExAC |
|
|
CA8628108 CA8628107 rs780571854 |
367 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1266322932 CA400088272 |
369 | M>T | No |
ClinGen gnomAD |
|
|
rs1300494217 CA400088201 |
373 | Q>* | No |
ClinGen gnomAD |
|
|
CA400087995 rs750539970 |
374 | D>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628075 rs750539970 |
374 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA400087996 rs1337177715 |
374 | D>Y | No |
ClinGen gnomAD |
|
|
CA8628074 rs762130963 |
375 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8628072 rs146230485 |
375 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs762130963 CA8628073 |
375 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763548777 CA8628070 |
377 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs1357983833 CA400087916 |
379 | L>F | No |
ClinGen gnomAD |
|
|
CA8628069 rs775899760 |
380 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA400087871 rs1394806275 |
381 | Q>* | No |
ClinGen gnomAD |
|
|
rs770450414 CA8628068 |
381 | Q>L | No |
ClinGen ExAC gnomAD |
|
|
rs143275072 CA8628066 |
384 | Q>E | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1294561321 CA400087813 |
385 | D>H | No |
ClinGen TOPMed |
|
|
rs528615260 CA291302376 |
386 | L>M | No |
ClinGen Ensembl |
|
|
CA291302374 rs61745061 |
387 | E>Q | No |
ClinGen TOPMed |
|
|
rs1476211377 CA400087759 |
388 | Q>* | No |
ClinGen gnomAD |
|
|
rs574222234 CA8628064 |
388 | Q>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1181395084 CA400087724 |
390 | G>S | No |
ClinGen gnomAD |
|
|
rs139515668 CA291302360 |
392 | E>A | No |
ClinGen ESP |
|
|
CA8628061 rs754809935 |
392 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754809935 CA8628062 |
392 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs909236762 CA291302355 |
393 | A>S | No |
ClinGen Ensembl |
|
| TCGA novel | 393 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs753793220 CA8628060 |
394 | T>A | No |
ClinGen ExAC TOPMed |
|
|
CA400087635 rs1196104038 |
395 | Q>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1196104038 CA400087633 |
395 | Q>R | No |
ClinGen TOPMed gnomAD |
|
|
rs779807693 CA8628058 |
396 | G>A | No |
ClinGen ExAC gnomAD |
|
|
CA400087598 rs1183711216 |
397 | L>P | No |
ClinGen TOPMed |
|
| TCGA novel | 398 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA400087572 rs1287102586 |
399 | A>T | No |
ClinGen gnomAD |
|
| TCGA novel | 399 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8628055 rs141621864 |
400 | G>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8628054 rs141621864 |
400 | G>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs751896094 CA8628053 |
400 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs952747097 CA291302329 |
401 | E>G | No |
ClinGen Ensembl |
|
|
CA8628050 rs761935218 |
401 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs765617992 CA8628049 |
402 | W>G | No |
ClinGen ExAC gnomAD |
|
|
rs866896396 CA291302295 |
403 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA400087502 rs1395353983 |
404 | P>A | No |
ClinGen gnomAD |
|
|
rs573416695 CA8628048 |
404 | P>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs934400867 CA291302293 |
405 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
CA400087491 rs1340753156 |
405 | P>S | No |
ClinGen TOPMed |
|
|
CA8628047 rs147542181 |
406 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8628046 rs375403419 |
407 | W>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA400087479 rs1305621337 |
407 | W>R | No |
ClinGen TOPMed gnomAD |
|
|
rs868498708 CA291302287 |
408 | E>G | No |
ClinGen Ensembl |
|
|
CA8628045 VAR_029511 rs17856535 |
411 | S>G | No |
ClinGen UniProt ExAC TOPMed dbSNP gnomAD |
|
|
rs143281920 CA8628043 |
411 | S>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs143281920 CA8628044 |
411 | S>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs748996909 CA8628042 |
413 | F>I | No |
ClinGen ExAC |
|
|
rs779903206 COSM188628 CA8628041 |
415 | A>T | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs1266944118 CA400087291 |
417 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1266944118 CA400087296 |
417 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
CA400087267 rs1567954987 |
418 | K>* | No |
ClinGen Ensembl |
|
|
rs376979287 CA8628038 |
419 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs757451151 CA8628037 |
420 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs372982459 CA8628035 |
420 | E>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs757451151 CA8628036 |
420 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1157827016 CA400087181 |
421 | S>N | No |
ClinGen TOPMed |
|
|
rs1240273831 CA400087161 |
422 | Q>K | No |
ClinGen gnomAD |
|
|
CA400087147 rs1370748536 |
423 | A>P | No |
ClinGen gnomAD |
|
|
CA400087148 rs1370748536 |
423 | A>T | No |
ClinGen gnomAD |
|
|
rs1402469564 CA400087142 |
423 | A>V | No |
ClinGen TOPMed |
|
|
rs764360298 CA8628033 |
424 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA400087083 rs142116967 |
425 | A>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA8628031 rs142116967 |
425 | A>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
No associated diseases with Q96FV2
No regional properties for Q96FV2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q96FV2 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular exosome | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| cysteine-type exopeptidase activity | Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. |
| dipeptidase activity | Catalysis of the hydrolysis of a dipeptide. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASSSPDSPC | SCDCFVSVPP | ASAIPAVIFA | KNSDRPRDEV | QEVVFVPAGT | HTPGSRLQCT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YIEVEQVSKT | HAVILSRPSW | LWGAEMGANE | HGVCIGNEAV | WTKEPVGEGE | ALLGMDLLRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ALERSSSAQE | ALHVITGLLE | HYGQGGNCLE | DAAPFSYHST | FLLADRTEAW | VLETAGRLWA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AQRIQEGARN | ISNQLSIGTD | ISAQHPELRT | HAQAKGWWDG | QGAFDFAQIF | SLTQQPVRME |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AAKARFQAGR | ELLRQRQGGI | TAEVMMGILR | DKESGICMDS | GGFRTTASMV | SVLPQDPTQP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CVHFLTATPD | PSRSVFKPFI | FGMGVAQAPQ | VLSPTFGAQD | PVRTLPRFQT | QVDRRHTLYR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GHQAALGLME | RDQDRGQQLQ | QKQQDLEQEG | LEATQGLLAG | EWAPPLWELG | SLFQAFVKRE |
| SQAYA |