Q6AYR8

PR
Gene name
Scrn2
Protein name
Secernin-2
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:360612
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

340-423 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6AYR8

Entry ID Method Resolution Chain Position Source
AF-Q6AYR8-F1 Predicted AlphaFoldDB

6 variants for Q6AYR8

Variant ID(s) Position Change Description Diseaes Association Provenance
rs105977299 24 I>F No EVA
rs197336317 130 A>E No EVA
rs3321933504 284 R>H No EVA
rs3321971096 363 Q>R No EVA
rs3321939546 378 R>W No EVA
rs8148292 403 A>P No EVA

No associated diseases with Q6AYR8

No regional properties for Q6AYR8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6AYR8

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
cysteine-type exopeptidase activity Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
dipeptidase activity Catalysis of the hydrolysis of a dipeptide.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96FV2 SCRN2 Secernin-2 Homo sapiens (Human) PR
Q9CZC8 Scrn1 Secernin-1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MASSSPDAPC SCDCFVSVPP ASAIPAVIFA KNSDRPRDEV QEVVFIPAGT HTPGSRLQCT
70 80 90 100 110 120
YIEVEQVWKT HAVILSRPSW LWGAEMGANE LGVCIGNEAV WTKEPVGEGE ALLGMDLLRL
130 140 150 160 170 180
ALERSSTAQA AVHVIAGLLD RYGQGGSCRE DPEPFCYHNT FLLADRTEAW VLETAGRLWA
190 200 210 220 230 240
AQRIQGGARN ISNQLSIGTD ISAEHPELRS HAKAQGWWSG QGVFDFAEVF SLTQQPVRME
250 260 270 280 290 300
AAKARFRAGC EMLQRQQGSI TAEVMMDILR NKESGICMDS GGFRTTASMV SVLPQDPTKP
310 320 330 340 350 360
CVHFLTATPD PSRSVFKPFI FEVGVSQPPQ VLSPTFGAQD PVRILPRFQT QVDRRHSLYR
370 380 390 400 410 420
GHQAALGLMD EQEQAQLRQE QQSLEQEGLE ALRGLLTGEQ TPAPQELGSL FQAFVEREHQ
VYA