AiPD: Autoinhibited Protein Database

Q96EK5

Gene name	KIFBP
Protein name	KIF-binding protein
Names	KIF1-binding protein, Kinesin family binding protein
Species	Homo sapiens (Human)
KEGG Pathway	hsa:26128
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-105 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-105 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

7 structures for Q96EK5

Entry ID	Method	Resolution	Chain	Position	Source
6ZPG	EM	460 A	A	1-621	PDB
6ZPH	EM	690 A	A	1-621	PDB
7RSI	EM	490 A	B	1-621	PDB
7RSQ	EM	380 A	B	1-621	PDB
7RYP	EM	480 A	B	1-621	PDB
7RYQ	EM	460 A	B	1-621	PDB
AF-Q96EK5-F1	Predicted				AlphaFoldDB

448 variants for Q96EK5

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA172377 RCV000888750 rs148768851 RCV000984789 RCV000146134	23	E>G	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA5529616 rs372223602 RCV002240734 RCV001105545	39	A>G	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs757781374 CA5529620 RCV001105546	41	A>P	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar ExAC TOPMed dbSNP gnomAD
rs767103634 RCV000449580	56	D>missing	Peripheral neuropathy [ClinVar]	Yes	ClinVar dbSNP
RCV001251036 rs770201721	57	E>*	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinVar dbSNP
RCV000712142 CA172373 RCV000600043 RCV000146132 VAR_023311 rs2255607	66	G>S	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs201068859 RCV002558055 RCV001105547 CA5529637	68	G>R	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD
RCV001794429 CA251942 rs121434515	84	E>*	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar dbSNP gnomAD
rs121434514 RCV001794428 CA251940	90	R>*	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar Ensembl dbSNP
RCV001105548 CA376899159 rs1339934594	101	L>F	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar dbSNP gnomAD
rs768592975 CA5529651 RCV001105550	108	T>A	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar ExAC TOPMed dbSNP gnomAD
rs62625033 RCV000146133 RCV000710152 RCV001106691 CA172375	173	M>T	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA376896175 RCV000984791 rs1589296239	189	P>S	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar Ensembl dbSNP
rs730882150 RCV000325234 RCV001795283 CA273767	200	S>*	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar ExAC TOPMed dbSNP gnomAD
RCV001795284 rs730882151	202	R>missing	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinVar dbSNP
RCV001106692 rs547582634 CA5529750	240	E>K	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar ExAC TOPMed dbSNP gnomAD
RCV001106693 rs749110699 RCV000503869 CA5529758	261	I>V	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar ExAC TOPMed dbSNP gnomAD
CA213244 RCV000146136 rs76319365	309	E>K	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar Ensembl dbSNP
CA376898230 rs1293340864 RCV000500069	326	Q>*	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar dbSNP gnomAD
rs769950460 RCV000334908 RCV002281081	362	A>missing	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinVar dbSNP
RCV000984790 RCV002235142 rs370902866 CA5529879	427	S>G	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD
RCV002240736 RCV001108857 CA5529886 rs764557349	442	R>T	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar ExAC TOPMed dbSNP gnomAD
rs1457900956 RCV001108859	458	T>I	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinVar dbSNP
RCV000984793 rs781469363 RCV000599038	506	I>missing	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinVar dbSNP
RCV002558090 CA5529926 RCV001108861 rs561448573	539	V>I	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD
CA209208270 RCV000732820 rs906050638 RCV002250687	549	R>*	Goldberg-Shprintzen megacolon syndrome Variant assessed as Somatic; impact. [ClinVar, NCI-TCGA]	Yes	ClinGen ClinVar Ensembl NCI-TCGA dbSNP
RCV001108862 rs1839004363	556	K>Q	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinVar dbSNP
rs1216570912 RCV000984792	565	E>missing	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinVar dbSNP
RCV001103701 CA5529943 rs374731910	590	A>T	Goldberg-Shprintzen megacolon syndrome [ClinVar]	Yes	ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD
CA209191387 rs756816553	5	P>L		No	ClinGen ExAC gnomAD
CA5529603 rs756816553	5	P>Q		No	ClinGen ExAC gnomAD
CA209191388 rs545527324	6	W>*		No	ClinGen TOPMed
CA376898256 rs1358858905	6	W>G		No	ClinGen TOPMed gnomAD
CA209191389 rs1024180629	7	A>G		No	ClinGen Ensembl
rs1843307363 RCV001289079	7	A>S		No	ClinVar dbSNP
TCGA novel	7	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1265597786 CA376898296	8	E>A		No	ClinGen gnomAD
rs553587755 CA5529604 RCV000501767	10	C>F		No	ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD
TCGA novel	11	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs747405986 CA5529607	13	F>L		No	ClinGen ExAC gnomAD
CA376898389 rs777015827	15	A>G		No	ClinGen ExAC TOPMed gnomAD
rs777015827 CA5529609	15	A>V		No	ClinGen ExAC TOPMed gnomAD
CA376898396 rs1481458834	16	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1589292346 CA376898401	17	L>V		No	ClinGen Ensembl
CA376898409 rs1181708378	18	A>S		No	ClinGen TOPMed
CA5529611 rs770113692	20	S>P		No	ClinGen ExAC gnomAD
CA209191390 rs1014852252	20	S>W		No	ClinGen Ensembl
rs1429970950 CA376898439	21	R>P		No	ClinGen gnomAD
rs1471707597 CA376898436	21	R>W		No	ClinGen TOPMed
rs775247494 CA376898472	25	H>P		No	ClinGen ExAC TOPMed gnomAD
CA5529614 rs775247494	25	H>R		No	ClinGen ExAC TOPMed gnomAD
rs1324154278 CA376898580	33	Y>H		No	ClinGen gnomAD
rs763921922 CA5529615	36	K>T		No	ClinGen ExAC gnomAD
CA376898648 rs1285747347	39	A>T		No	ClinGen gnomAD
rs372223602 CA5529617	39	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs749960762 CA5529619	40	R>W		No	ClinGen ExAC gnomAD
rs1283885170 CA376898679	43	L>V		No	ClinGen gnomAD
rs1226222903 CA376898735	48	A>G		No	ClinGen TOPMed
rs747425094 CA5529622	48	A>P		No	ClinGen ExAC
CA209191393 rs897870475	50	L>R		No	ClinGen TOPMed
CA376898756 rs1041795333	51	G>R		No	ClinGen TOPMed
CA209191395 rs1041795333	51	G>S		No	ClinGen TOPMed
CA5529623 rs755489046	52	P>L		No	ClinGen ExAC TOPMed gnomAD
CA376898763 rs1480034789	52	P>S		No	ClinGen gnomAD
CA376898772 rs1406956910	54	P>T		No	ClinGen TOPMed
rs1426169338 CA376898786	56	D>N		No	ClinGen gnomAD
CA5529627 rs770201721	57	E>K		No	ClinGen ExAC gnomAD
rs773512678 RCV000500164 CA5529628	59	E>K		No	ClinGen ClinVar ExAC TOPMed dbSNP gnomAD
rs749414163 CA5529629	60	R>W		No	ClinGen ExAC gnomAD
CA5529630 rs371300766	61	P>R		No	ClinGen ExAC TOPMed gnomAD
CA5529631 rs774462618	63	A>G		No	ClinGen ExAC gnomAD
COSM1348764 CA376898837 rs774462618	63	A>V	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA209191397 rs935579771	64	E>K		No	ClinGen TOPMed
CA5529633 rs2255607	66	G>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5529634 rs2255607	66	G>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs750004526 CA5529636	67	P>Q		No	ClinGen ExAC TOPMed gnomAD
rs764872990 CA5529635	67	P>T		No	ClinGen ExAC TOPMed gnomAD
rs201068859 CA5529638	68	G>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1206217818 CA376898861	68	G>D		No	ClinGen TOPMed
rs201068859 CA376898860	68	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA376898864 rs1292526099	69	A>T		No	ClinGen gnomAD
CA376898868 rs1490219246	69	A>V		No	ClinGen gnomAD
rs1393955776 CA376898873	70	G>D		No	ClinGen gnomAD
rs1252658012 CA376898879	71	D>G		No	ClinGen gnomAD
rs1012864536 CA209191398	72	H>N		No	ClinGen Ensembl
rs755612919 CA376898929	77	P>L		No	ClinGen ExAC TOPMed gnomAD
rs755612919 CA5529641	77	P>Q		No	ClinGen ExAC TOPMed gnomAD
rs755612919 CA376898927	77	P>R		No	ClinGen ExAC TOPMed gnomAD
rs1180741256 CA376898925	77	P>S		No	ClinGen gnomAD
rs1163865456 CA376898932	78	A>T		No	ClinGen gnomAD
rs1247242658 CA376898941	79	E>K		No	ClinGen gnomAD
rs192748736 CA209191400	84	E>D		No	ClinGen 1000Genomes
CA376898990 rs121434515	84	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs778077029 CA5529646	85	G>R		No	ClinGen ExAC gnomAD
CA376899003 rs778077029	85	G>W		No	ClinGen ExAC gnomAD
rs749517204 CA5529647	86	P>S		No	ClinGen ExAC gnomAD
CA376899022 rs1328531861	87	V>F		No	ClinGen gnomAD
CA209191401 rs1014883362	88	A>T		No	ClinGen TOPMed
rs1387463152 CA376899038	89	Q>K		No	ClinGen TOPMed
CA376899041 rs1334373963	89	Q>R		No	ClinGen gnomAD
CA376899050 rs992870301	90	R>L		No	ClinGen TOPMed gnomAD
CA209191402 rs992870301	90	R>Q		No	ClinGen TOPMed gnomAD
CA376899082 rs1316056840	94	L>V		No	ClinGen TOPMed gnomAD
CA376899110 rs1358806567	97	I>V		No	ClinGen gnomAD
rs1383187078 CA376899117	98	E>K		No	ClinGen TOPMed
CA5529649 rs774361181	99	F>V		No	ClinGen ExAC gnomAD
rs1219404864 COSM1255676 CA376899208	105	H>R	oesophagus [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
rs912912274 CA209191403	106	I>T		No	ClinGen TOPMed gnomAD
CA376899228 rs745948039	107	D>N		No	ClinGen ExAC gnomAD
CA5529650 rs745948039	107	D>Y		No	ClinGen ExAC gnomAD
rs761628784 CA5529654	109	E>D		No	ClinGen ExAC gnomAD
rs1462900645 CA376899275	111	L>R		No	ClinGen gnomAD
rs1167874163 CA376899283	112	S>L		No	ClinGen gnomAD
CA376899292 rs1262056242	114	G>R		No	ClinGen TOPMed
CA5529655 rs769531440	116	E>G		No	ClinGen ExAC gnomAD
rs773038576 CA5529656	117	H>P		No	ClinGen ExAC gnomAD
CA209191407 rs1030239043	117	H>Q		No	ClinGen gnomAD
rs773038576 CA376899342	117	H>R		No	ClinGen ExAC gnomAD
CA376899338 rs1337631572	117	H>Y		No	ClinGen gnomAD
rs1589292460 CA376899357	119	V>G		No	ClinGen Ensembl
CA376899376 rs1394527585	120	K>N		No	ClinGen gnomAD
CA5529657 rs372695759	123	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA209191409 rs986393623	124	L>R		No	ClinGen TOPMed
CA376893180 rs1308188448	126	R>L		No	ClinGen TOPMed gnomAD
CA376893186 rs751092379	127	R>G		No	ClinGen ExAC TOPMed gnomAD
CA5529660 rs759061022	127	R>K		No	ClinGen ExAC gnomAD
rs768145533 CA5529661	128	Y>C		No	ClinGen ExAC TOPMed gnomAD
rs1589292473 CA376893207	128	Y>D		No	ClinGen Ensembl
CA5529662 rs753204138	129	R>G		No	ClinGen ExAC gnomAD
rs1459656007 CA376893226	129	R>L		No	ClinGen gnomAD
CA5529665 CA376893245 rs540172119	132	H>Q		No	ClinGen 1000Genomes ExAC gnomAD
CA209202130 rs200399485	134	C>G		No	ClinGen 1000Genomes
CA5529667 rs143950359	135	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA376893263 rs1159688038	135	I>S		No	ClinGen gnomAD
rs757478269 CA5529666	135	I>V		No	ClinGen ExAC
rs772098884 CA5529669	136	S>T		No	ClinGen ExAC gnomAD
rs1476325494 CA376893272	137	L>V		No	ClinGen TOPMed
rs1050330380 CA209202141	139	I>N		No	ClinGen TOPMed gnomAD
rs1050330380 CA376893289	139	I>T		No	ClinGen TOPMed gnomAD
rs781131113 CA5529670	139	I>V		No	ClinGen ExAC gnomAD
CA5529671 rs529028747	140	Q>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs865809614 CA209202148	141	A>G		No	ClinGen gnomAD
CA209202145 rs375084646	141	A>T		No	ClinGen Ensembl
rs865809614 CA376893313	141	A>V		No	ClinGen gnomAD
TCGA novel	142	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA376893325 rs1290898365	142	Q>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA5529692 rs769682005	143	N>D		No	ClinGen ExAC TOPMed gnomAD
CA5529694 rs749043896	154	E>D		No	ClinGen ExAC gnomAD
CA209204688 rs770722517	155	I>L		No	ClinGen ExAC gnomAD
CA5529695 rs770722517	155	I>V		No	ClinGen ExAC gnomAD
CA376895243 rs1387131459	160	A>T		No	ClinGen gnomAD
rs1589295169 CA376895300	162	L>V		No	ClinGen Ensembl
rs774262677 CA5529696	163	E>Q		No	ClinGen ExAC gnomAD
rs1302467817 CA376895352	165	S>*		No	ClinGen gnomAD
rs1347981384 CA376895382	167	A>V		No	ClinGen gnomAD
rs1044770486 CA209204696	171	Q>H		No	ClinGen TOPMed
rs200596309 CA376895455	173	M>L		No	ClinGen TOPMed
rs200596309 CA209204698 RCV000992248	173	M>V		No	ClinGen ClinVar TOPMed dbSNP
rs1257801340 CA376895474	174	K>E		No	ClinGen TOPMed gnomAD
rs144317643 CA5529699	175	E>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA5529712 rs757109189 COSM427813	176	V>F	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs1564636741 CA376896045	178	S>N		No	ClinGen Ensembl
rs757514844	180	P>missing	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA209205883 rs1047715298	181	L>F		No	ClinGen TOPMed gnomAD
TCGA novel	182	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
RCV000992249 CA5529714 rs112642097	184	T>A		No	ClinGen ClinVar 1000Genomes ESP TOPMed dbSNP gnomAD
CA209205885 rs112642097	184	T>P		No	ClinGen 1000Genomes ESP TOPMed gnomAD
RCV000192664 RCV002229020 rs200098813 CA205635	186	R>C		No	ClinGen ClinVar 1000Genomes ExAC dbSNP gnomAD
rs139483880 CA5529716	186	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1197071935 CA376896155	187	F>C		No	ClinGen gnomAD
RCV000193127 rs771863463 CA206400	188	L>I		No	ClinGen ClinVar ExAC dbSNP gnomAD
rs1464792155 CA376896191	190	E>A		No	ClinGen gnomAD
CA209205892 rs979798155	191	E>K		No	ClinGen Ensembl
rs926983945 CA209205895	192	E>G		No	ClinGen TOPMed
CA5529717 rs377072770	195	T>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA5529719 rs768162436	196	E>K		No	ClinGen ExAC gnomAD
CA209205905 rs866585619	197	Q>R		No	ClinGen Ensembl
rs1157358651 CA376896341	199	R>I		No	ClinGen TOPMed
CA376896374 rs1564636963	202	R>S		No	ClinGen Ensembl
rs746722910 CA209206076	206	V>F		No	ClinGen ExAC TOPMed gnomAD
rs746722910 CA5529736	206	V>I		No	ClinGen ExAC TOPMed gnomAD
CA376896407 rs1346531121	207	Y>C		No	ClinGen gnomAD
rs1383529353 CA376896439	212	Y>H		No	ClinGen TOPMed
rs1224561733 CA376896447	213	Y>D		No	ClinGen gnomAD
CA5529737 COSM299844 rs768162943	215	A>V	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA376896466 rs1297155405	216	Q>*		No	ClinGen TOPMed
rs935472274 CA209206080	216	Q>P		No	ClinGen TOPMed
CA376896492 rs1487370056	218	Y>D		No	ClinGen gnomAD
rs370670715 CA5529738	219	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA376896547 rs1289198105	221	L>P		No	ClinGen TOPMed
CA5529739 rs747600573	222	E>K		No	ClinGen ExAC TOPMed gnomAD
CA5529740 rs368916440	223	M>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA5529741 rs781257334	227	A>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	228	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1388953594 CA376896632	228	A>T		No	ClinGen TOPMed
CA376896640 rs1365348518	228	A>V		No	ClinGen gnomAD
rs191873145 CA5529743	230	Y>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1377923102 CA376896675	231	C>S		No	ClinGen gnomAD
CA5529745 rs759865249	233	S>G		No	ClinGen ExAC
rs752833136 COSM1348766 CA5529747	237	R>C	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA5529748 rs760604068	237	R>H		No	ClinGen ExAC TOPMed gnomAD
CA376896719 rs760604068	237	R>L		No	ClinGen ExAC TOPMed gnomAD
CA209206102 rs997199629	238	Q>H		No	ClinGen TOPMed
rs547582634 CA5529749	240	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA5529752 rs141052402	243	A>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA209206113 rs1016134527	244	Y>D		No	ClinGen TOPMed
CA5529754 rs140826893	245	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA376896850 rs1248349112	247	I>M		No	ClinGen gnomAD
CA376896852 rs1296096605	248	E>K		No	ClinGen TOPMed
CA376896897 rs1355494591	251	I>V		No	ClinGen gnomAD
rs937189116 CA209206119	252	N>K		No	ClinGen Ensembl
CA5529755 rs780651935	252	N>S		No	ClinGen ExAC gnomAD
CA376896948 rs1252367280	254	A>V		No	ClinGen gnomAD
CA209206121 rs866036954	256	L>F		No	ClinGen Ensembl
rs1177613996 CA376896971	256	L>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA5529756 rs747701445	257	S>A		No	ClinGen ExAC gnomAD
rs1386003298 CA376896992	258	Q>*		No	ClinGen TOPMed
rs572485003 CA5529757	260	Y>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA376897023 rs572485003	260	Y>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA376897079 rs1162016885	263	K>R		No	ClinGen gnomAD
rs766214681 CA5529769	264	L>Q		No	ClinGen ExAC TOPMed gnomAD
rs149706162 CA5529771	265	C>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA376897295 rs1465710834	267	M>I		No	ClinGen TOPMed
CA5529772 rs374135003	267	M>V		No	ClinGen ESP ExAC
rs1364436073 CA376897309	269	A>G		No	ClinGen gnomAD
rs752246398 CA5529773	269	A>S		No	ClinGen ExAC gnomAD
CA376897306 rs752246398	269	A>T		No	ClinGen ExAC gnomAD
rs755744684 CA5529775	271	H>N		No	ClinGen ExAC gnomAD
rs755744684 CA5529774	271	H>Y		No	ClinGen ExAC gnomAD
CA376897544 rs1376167494	286	I>V		No	ClinGen TOPMed
CA5529778 rs779217930	288	A>V		No	ClinGen ExAC gnomAD
CA376897585 rs1261835762	289	T>A		No	ClinGen gnomAD
rs201438642 CA5529779	292	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA5529780 rs201438642	292	T>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA376897892 rs1213874017	297	G>R		No	ClinGen gnomAD
TCGA novel	297	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1261742653 CA376897925	299	V>A		No	ClinGen gnomAD
rs941844673 CA209207085	300	P>S		No	ClinGen TOPMed gnomAD
TCGA novel	300	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs149809657 CA5529793	301	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA376897966 rs1431618931	302	L>P		No	ClinGen gnomAD
rs918976095 CA209207088	305	Q>H		No	ClinGen gnomAD
rs753347618 CA5529794	307	K>R		No	ClinGen ExAC gnomAD
CA5529795 rs756713727	310	I>T		No	ClinGen ExAC gnomAD
CA5529796 rs779495747	311	A>T		No	ClinGen ExAC gnomAD
CA376898047 rs1413526451	314	W>*		No	ClinGen TOPMed gnomAD
rs1437122309 CA376898056	314	W>C		No	ClinGen gnomAD
CA376898045 rs1180857940	314	W>R		No	ClinGen gnomAD
CA376898048 rs1413526451	314	W>S		No	ClinGen TOPMed gnomAD
rs746409140 CA5529802	319	L>S		No	ClinGen ExAC gnomAD
CA209207093 rs978909163	320	T>P		No	ClinGen TOPMed
CA376898133 rs200525249	321	L>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs199510149 CA209207095	321	L>P		No	ClinGen 1000Genomes
rs200525249 CA5529803	321	L>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1352329978 CA376898147	322	M>I		No	ClinGen gnomAD
rs141279010 CA5529805	322	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs769013695 CA5529806	325	A>T		No	ClinGen ExAC TOPMed gnomAD
CA376898229 rs1293340864	326	Q>E		No	ClinGen gnomAD
CA5529834 rs749327406	331	D>N		No	ClinGen ExAC TOPMed gnomAD
rs374306964 CA209208242	332	N>K		No	ClinGen ESP gnomAD
rs771905210 CA5529835	332	N>S		No	ClinGen ExAC gnomAD
CA376899608 rs1411453116	333	I>K		No	ClinGen gnomAD
rs1181204651 CA376899601	333	I>V		No	ClinGen gnomAD
CA209208243 rs113952834	334	G>A		No	ClinGen gnomAD
CA376899641 rs113952834	334	G>E		No	ClinGen gnomAD
rs1430252870 CA376899628	334	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA209208244 rs774495984	335	E>G		No	ClinGen Ensembl
rs775363378 CA5529836	336	L>R		No	ClinGen ExAC gnomAD
CA376899711 rs760482247	337	D>H		No	ClinGen ExAC TOPMed gnomAD
CA5529837 rs760482247	337	D>N		No	ClinGen ExAC TOPMed gnomAD
CA209208245 rs916055618	339	D>N		No	ClinGen gnomAD
CA376899819 rs1288749960	342	S>P		No	ClinGen TOPMed
CA376899821 rs1446733493	342	S>Y		No	ClinGen gnomAD
rs776378534 CA5529838	344	L>F		No	ClinGen ExAC gnomAD
rs761439410 CA5529840	345	R>K		No	ClinGen ExAC gnomAD
CA5529841 rs764929585	349	K>E		No	ClinGen ExAC gnomAD
rs762458711 CA5529843	350	K>T		No	ClinGen ExAC gnomAD
CA376900001 rs1362774155	354	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA209208246 rs994920889	356	E>G		No	ClinGen TOPMed
CA5529845 rs138090713	356	E>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA5529848 rs371267544	359	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA5529847 COSM275692 rs755522222	359	R>W	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA5529850 rs756300309	360	K>E		No	ClinGen ExAC TOPMed gnomAD
CA376900087 rs756300309	360	K>Q		No	ClinGen ExAC TOPMed gnomAD
rs769950460	362	A>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs1036928323 CA209208248	363	V>E		No	ClinGen Ensembl
CA209208249 rs138802223	364	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA5529853 rs374297499	365	F>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1245098587 CA376900173	366	G>E		No	ClinGen TOPMed
CA376900166 rs1346485433	366	G>R		No	ClinGen TOPMed gnomAD
CA376900213 rs1333565207	368	G>D		No	ClinGen gnomAD
COSM3978739 rs200669180 CA5529855	368	G>S	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs1342924055 CA376900236	369	E>K		No	ClinGen TOPMed
rs200179572 CA209208251	371	C>S		No	ClinGen 1000Genomes
rs202157293 CA209208250	371	C>S		No	ClinGen Ensembl
COSM685542 rs770724316 CA5529857	373	A>T	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1276557114 CA376900343	374	I>M		No	ClinGen gnomAD
CA5529859 rs761611047	374	I>V		No	ClinGen ExAC gnomAD
TCGA novel	375	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA376900374 rs776459431	376	A>S		No	ClinGen ExAC gnomAD
CA5529860 rs776459431	376	A>T		No	ClinGen ExAC gnomAD
CA209208252 rs960846058	377	V>I		No	ClinGen TOPMed
rs1217236521 CA376900427	379	E>G		No	ClinGen TOPMed gnomAD
rs1487268466 CA376900472	381	V>A		No	ClinGen gnomAD
CA10606528 rs886044247 RCV000388627	381	V>M		No	ClinGen ClinVar dbSNP gnomAD
CA209208253 rs371981506	384	L>F		No	ClinGen ESP TOPMed
CA5529862 rs762394220	388	D>E		No	ClinGen ExAC TOPMed
rs1247087961 CA376900693	393	R>K		No	ClinGen gnomAD
COSM919852 rs766038589 CA5529863	394	E>*	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA5529865 rs760190886	397	L>F		No	ClinGen ExAC
rs768129181 CA376900741	398	L>V		No	ClinGen ExAC TOPMed gnomAD
CA5529867 rs753004563	399	G>C		No	ClinGen ExAC gnomAD
rs756457508 CA5529868	402	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA209208254 rs902198961	404	F>I		No	ClinGen Ensembl
TCGA novel	404	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	406	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5529870 rs754137248	407	K>N		No	ClinGen ExAC gnomAD
CA376900880 rs1332083800	410	F>L		No	ClinGen TOPMed gnomAD
rs779030658 CA5529872	411	Q>*		No	ClinGen ExAC gnomAD
rs1379196173 CA376900910	412	I>T		No	ClinGen TOPMed gnomAD
rs745934722 CA5529873	412	I>V		No	ClinGen ExAC gnomAD
CA376900918 rs1269240713	413	D>Y		No	ClinGen TOPMed
CA376900934 rs1338360350	414	G>A		No	ClinGen TOPMed
CA5529874 rs754921517	414	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1031934038 CA209208256	415	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA209208257 rs1031934038	415	Y>F		No	ClinGen Ensembl
rs999150215 CA209208255	415	Y>N		No	ClinGen Ensembl
rs1285409321 CA376900948	416	V>I		No	ClinGen gnomAD
CA376900971 rs1564639516 RCV000761724	418	D>N		No	ClinGen ClinVar Ensembl dbSNP
CA376900985 rs1351350616	419	H>Y		No	ClinGen gnomAD
CA5529875 rs377298939	420	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA209208258 rs960310811	422	V>A		No	ClinGen Ensembl
RCV000502283 rs1450869089 CA376901035	423	V>I		No	ClinGen ClinVar TOPMed dbSNP gnomAD
CA5529877 rs769584821	424	Q>*		No	ClinGen ExAC gnomAD
rs769584821 CA376901050	424	Q>E		No	ClinGen ExAC gnomAD
rs1014919970 CA209208259	424	Q>R		No	ClinGen Ensembl
rs772862957 CA5529878	425	D>G		No	ClinGen ExAC gnomAD
CA5529880 rs770706536	428	A>S		No	ClinGen ExAC TOPMed gnomAD
CA5529881 rs774066072	432	V>L		No	ClinGen ExAC gnomAD
CA376901852 rs373810468	433	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs373810468 CA5529882	433	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1391894394 CA376901880	435	F>V		No	ClinGen gnomAD
CA209208260 rs932630326	436	F>L		No	ClinGen TOPMed
rs1402651253 CA376901967	440	M>V		No	ClinGen gnomAD
rs377744293 CA5529888	443	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs757532870 CA5529887	443	R>W		No	ClinGen ExAC TOPMed gnomAD
CA5529889 rs750506715	449	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA5529890 rs201404470	449	R>H		No	ClinGen 1000Genomes ExAC gnomAD
CA5529891 rs201404470	449	R>P		No	ClinGen 1000Genomes ExAC gnomAD
rs748167932 CA5529892	452	A>V		No	ClinGen ExAC gnomAD
TCGA novel	453	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA209208262 rs909933445	453	M>V		No	ClinGen Ensembl
CA376902190 rs1589299061	458	T>P		No	ClinGen Ensembl
rs1457900956 CA376902198	458	T>S		No	ClinGen gnomAD
rs1235802814 CA376902209	459	V>A		No	ClinGen gnomAD
CA5529894 rs777693937	459	V>I		No	ClinGen ExAC gnomAD
CA5529895 rs749084385	461	L>P		No	ClinGen ExAC gnomAD
CA5529898 rs774102690	465	Y>D		No	ClinGen ExAC gnomAD
rs1402950491 CA376902315	467	L>P		No	ClinGen gnomAD
CA5529901 rs761310113	470	N>S		No	ClinGen ExAC gnomAD
CA376902389 rs1397928504	473	I>M		No	ClinGen gnomAD
rs1334941703 CA376902390	474	Q>K		No	ClinGen gnomAD
rs764494346 CA5529902	479	H>D		No	ClinGen ExAC gnomAD
rs1554843825 COSM3375518 CA376902431	479	H>R	pancreas [Cosmic]	No	ClinGen cosmic curated Ensembl
CA5529903 rs375318030	483	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs762099157 CA5529904	484	M>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA376902484 rs1219083406	486	D>G		No	ClinGen TOPMed
rs933931987 CA209208263	489	V>A		No	ClinGen TOPMed
CA376902504 rs1217616883	489	V>F		No	ClinGen gnomAD
rs147288545 CA5529906	490	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1564639628 CA376902512	490	A>V		No	ClinGen Ensembl
TCGA novel	492	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5529908 rs766522607	492	A>V		No	ClinGen ExAC gnomAD
CA376902539 rs946518833	494	R>S		No	ClinGen TOPMed gnomAD
rs139261765 CA5529909	495	L>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs763853555 CA209208265	497	D>G		No	ClinGen Ensembl
CA5529910 rs756138362	501	H>P		No	ClinGen ExAC TOPMed gnomAD
CA376902581 rs756138362	501	H>R		No	ClinGen ExAC TOPMed gnomAD
CA376902580 rs1426204282	501	H>Y		No	ClinGen gnomAD
rs1371483818 CA376902591	502	I>M		No	ClinGen gnomAD
CA5529912 rs753695346	503	V>L		No	ClinGen ExAC gnomAD
rs1589299115 CA376902617	506	I>T		No	ClinGen Ensembl
rs1412898890 CA376902624	507	N>S		No	ClinGen TOPMed
CA376902634 rs1404262531	508	N>K		No	ClinGen TOPMed
TCGA novel	509	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA209208267 rs1056181592	510	N>S		No	ClinGen Ensembl
CA5529915 rs757081898	512	S>*		No	ClinGen ExAC gnomAD
CA376902658 rs1401634537	512	S>P		No	ClinGen gnomAD
rs1300021171 CA376902662	513	A>S		No	ClinGen TOPMed gnomAD
CA376902664 rs1300021171	513	A>T		No	ClinGen TOPMed gnomAD
rs541494160 CA5529917	524	L>R		No	ClinGen 1000Genomes ExAC gnomAD
CA376902758 rs1233563985	526	D>Y		No	ClinGen TOPMed gnomAD
CA5529919 rs779684131	528	N>D		No	ClinGen ExAC TOPMed gnomAD
rs779684131 CA209208268	528	N>H		No	ClinGen ExAC TOPMed gnomAD
rs746439491 CA5529920	530	V>L		No	ClinGen ExAC gnomAD
CA5529921 rs769220890	531	F>L		No	ClinGen ExAC gnomAD
CA376902819 rs1564639686	531	F>L		No	ClinGen Ensembl
rs1241920948 CA376902831	532	P>L		No	ClinGen TOPMed
rs1564639691 CA376902837	533	E>A		No	ClinGen Ensembl
CA5529922 rs777074091	533	E>K		No	ClinGen ExAC gnomAD
CA5529923 rs762195530	534	H>P		No	ClinGen ExAC
TCGA novel	534	H>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1014537937 CA209208269	535	I>T		No	ClinGen Ensembl
rs773542445 CA5529925	535	I>V		No	ClinGen ExAC gnomAD
CA376902865 rs1589299144	536	G>E		No	ClinGen Ensembl
CA376902889 rs1564639703	540	L>F		No	ClinGen Ensembl
CA5529927 rs374074903	541	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs368405054 RCV000516403 RCV002525045 CA5529928	541	R>H		No	ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD
rs753869868 CA5529931	543	A>T		No	ClinGen ExAC gnomAD
rs1419050253 CA376902941	548	F>L		No	ClinGen gnomAD
rs1419050253 CA376902942	548	F>V		No	ClinGen gnomAD
rs1307543514 CA376902957	550	V>I		No	ClinGen TOPMed
rs147387308 CA5529933	552	R>C		No	ClinGen ESP ExAC gnomAD
rs368655395 CA5529935	552	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs368655395 CA5529934	552	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs147387308 CA376902978	552	R>S		No	ClinGen ESP ExAC gnomAD
rs1300238727 CA376903016	555	G>D		No	ClinGen gnomAD
CA209208272 rs866474350	556	K>R		No	ClinGen Ensembl
TCGA novel	557	I>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA5529937 rs768011424	558	I>V		No	ClinGen ExAC gnomAD
CA5529938 rs372342802	562	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA376903105 rs1355001362	564	K>Q		No	ClinGen TOPMed gnomAD
rs770269897 CA376903222	573	L>*		No	ClinGen ExAC TOPMed gnomAD
CA5529940 rs770269897	573	L>W		No	ClinGen ExAC TOPMed gnomAD
CA376903238 rs1160246349	574	E>Q		No	ClinGen TOPMed
CA5529941 rs773630664	577	K>R		No	ClinGen ExAC gnomAD
rs972791290 CA209208273	578	F>C		No	ClinGen TOPMed
TCGA novel	578	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA209208274 rs954046550	580	V>I		No	ClinGen TOPMed
rs1297508616 CA376903401	583	C>S		No	ClinGen Ensembl
rs1179791643 CA376903409	583	C>Y		No	ClinGen TOPMed
CA376903448 rs1180539772	585	K>N		No	ClinGen TOPMed gnomAD
rs1351395042 CA376903556	590	A>V		No	ClinGen gnomAD
CA376903570 rs1458281300	591	Q>R		No	ClinGen gnomAD
rs201007879 CA209208276	593	I>V		No	ClinGen 1000Genomes TOPMed
CA376903629 rs1391756244	594	E>Q		No	ClinGen gnomAD
rs775700337 CA5529947	601	K>E		No	ClinGen ExAC gnomAD
rs1564639777 CA376903895	603	M>T		No	ClinGen Ensembl
CA5529948 rs761910393	605	S>N		No	ClinGen ExAC gnomAD
rs1222693850 CA376904010	608	P>L		No	ClinGen gnomAD
rs1354919783 CA376904017	609	T>A		No	ClinGen TOPMed
rs552921995 CA209208277	610	K>N		No	ClinGen 1000Genomes
CA376904095 rs1272965370	612	E>V		No	ClinGen TOPMed gnomAD
rs758079903 CA5529951	618	M>T		No	ClinGen ExAC gnomAD
CA376904252 rs1589299224	619	A>T		No	ClinGen Ensembl
CA209208278 rs985410422	620	L>R		No	ClinGen TOPMed
CA209208279 rs911087411	621	T>I		No	ClinGen Ensembl
CA5529952 rs766086695	621	T>S		No	ClinGen ExAC gnomAD

1 associated diseases with Q96EK5

[MIM: 609460]: Goldberg-Shprintzen syndrome (GOSHS)

A disorder characterized by intellectual disability, microcephaly, and dysmorphic facial features. Most patients also have Hirschsprung disease. {ECO:0000269|PubMed:15883926, ECO:0000269|PubMed:23427148}. Note=The disease is caused by variants affecting the gene represented in this entry.

Without disease ID

A disorder characterized by intellectual disability, microcephaly, and dysmorphic facial features. Most patients also have Hirschsprung disease. {ECO:0000269|PubMed:15883926, ECO:0000269|PubMed:23427148}. Note=The disease is caused by variants affecting the gene represented in this entry.

No regional properties for Q96EK5

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q96EK5

Functions

		Description
EC Number
Subcellular Localization	Cytoplasm, cytoskeleton
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

2 GO annotations of cellular component

Name	Definition
cytoskeleton	A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name	Definition
kinesin binding	Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.

5 GO annotations of biological process

Name	Definition
central nervous system projection neuron axonogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
in utero embryonic development	The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
microtubule cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
mitochondrial transport	Transport of substances into, out of or within a mitochondrion.
neuron projection maintenance	The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

3 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q3SYS9	KIFBP	KIF-binding protein	Bos taurus (Bovine)	PR
Q6ZPU9	Kifbp	KIF-binding protein	Mus musculus (Mouse)	PR
Q0IIZ5	Kifbp	KIF-binding protein	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR

10	20	30	40	50	60
MANVPWAEVC	EKFQAALALS	RVELHKNPEK	EPYKSKYSAR	ALLEEVKALL	GPAPEDEDER
70	80	90	100	110	120
PEAEDGPGAG	DHALGLPAEV	VEPEGPVAQR	AVRLAVIEFH	LGVNHIDTEE	LSAGEEHLVK
130	140	150	160	170	180
CLRLLRRYRL	SHDCISLCIQ	AQNNLGILWS	EREEIETAQA	YLESSEALYN	QYMKEVGSPP
190	200	210	220	230	240
LDPTERFLPE	EEKLTEQERS	KRFEKVYTHN	LYYLAQVYQH	LEMFEKAAHY	CHSTLKRQLE
250	260	270	280	290	300
HNAYHPIEWA	INAATLSQFY	INKLCFMEAR	HCLSAANVIF	GQTGKISATE	DTPEAEGEVP
310	320	330	340	350	360
ELYHQRKGEI	ARCWIKYCLT	LMQNAQLSMQ	DNIGELDLDK	QSELRALRKK	ELDEEESIRK
370	380	390	400	410	420
KAVQFGTGEL	CDAISAVEEK	VSYLRPLDFE	EARELFLLGQ	HYVFEAKEFF	QIDGYVTDHI
430	440	450	460	470	480
EVVQDHSALF	KVLAFFETDM	ERRCKMHKRR	IAMLEPLTVD	LNPQYYLLVN	RQIQFEIAHA
490	500	510	520	530	540
YYDMMDLKVA	IADRLRDPDS	HIVKKINNLN	KSALKYYQLF	LDSLRDPNKV	FPEHIGEDVL
550	560	570	580	590	600
RPAMLAKFRV	ARLYGKIITA	DPKKELENLA	TSLEHYKFIV	DYCEKHPEAA	QEIEVELELS
610	620
KEMVSLLPTK	MERFRTKMAL	T