Q6ZPU9
Gene name |
Kifbp |
Protein name |
KIF-binding protein |
Names |
KIF1-binding protein |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:72320 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6ZPU9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6ZPU9-F1 | Predicted | AlphaFoldDB |
15 variants for Q6ZPU9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs235625046 | 4 | A>T | No | EVA | |
| rs227146507 | 72 | G>A | No | EVA | |
| rs225312117 | 283 | P>T | No | EVA | |
| rs3389095856 | 285 | T>R | No | EVA | |
| rs3389080374 | 291 | V>G | No | EVA | |
| rs3389102781 | 300 | H>P | No | EVA | |
| rs3389102760 | 300 | H>Q | No | EVA | |
| rs3389095876 | 302 | R>* | No | EVA | |
| rs3412787426 | 303 | K>* | No | EVA | |
| rs3389095879 | 384 | D>E | No | EVA | |
| rs3389046443 | 428 | V>L | No | EVA | |
| rs3389105736 | 477 | Y>* | No | EVA | |
| rs3389069890 | 496 | S>L | No | EVA | |
| rs3389109023 | 571 | H>D | No | EVA | |
| rs3389102624 | 609 | R>G | No | EVA |
No associated diseases with Q6ZPU9
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| kinesin binding | Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| central nervous system projection neuron axonogenesis | Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region. |
| in utero embryonic development | The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. |
| microtubule cytoskeleton organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. |
| mitochondrial transport | Transport of substances into, out of or within a mitochondrion. |
| neuron projection maintenance | The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MANAPGPEIR | EKFQAALALS | RVELHKNPEK | EPYKSKYGAR | ALLEEVRALL | GPAPEDEDEP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AADDGPGDQA | LGAGEPREAE | GPGAQRALRL | AVVEFHLGVN | HIDTEELSAG | EEHLVRCLSL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRPYRLSLGC | VSLYIQAQNN | LGILWSEREE | IETARTYLES | SEALYSQYMK | EIGSPPLDPT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EHFLPEEEKL | TEQERSKRFE | KVYTHNLYYL | AQVYQHMEMF | EKAAHYCHST | LKRQLEHNAY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HPMEWAINAA | TLSQFYINKL | CFMEARHCLS | AANVIFGQTG | KIPATEDTPE | VEGDVPELYH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QRKGEIARCW | IKYCLTLMQN | AQLSMQDNIG | ELDLDKQSEL | RALRKKELDE | EESVRKRAVQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FGTGELCDAI | SAVEEKVRYL | RPLDFEEARE | LFLLGQHYVC | EAKEFFQIDG | YVTDHIEVVQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DHSALFKVLS | FFEADMERRC | KMHKRRIAML | EPLTVDLNPQ | YYLLVSRQIQ | FEIAHAYYDM |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MDLKVAIADK | LRDPDSHIVK | KINSLNKSAL | KYYQLFLDSL | RDPNKVFPEH | IGEDVLRPAM |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LAKFRVARLY | GKIITADPKK | ELENLATSLE | HYKFIVDYCE | THPEAAQEIE | VELELSKEMV |
| 610 | |||||
| SLLPTKMERF | RAKMALT |