Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0IIZ5

Entry ID Method Resolution Chain Position Source
AF-Q0IIZ5-F1 Predicted AlphaFoldDB

No variants for Q0IIZ5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0IIZ5

No associated diseases with Q0IIZ5

No regional properties for Q0IIZ5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q0IIZ5

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

4 GO annotations of biological process

Name Definition
central nervous system projection neuron axonogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
mitochondrial transport Transport of substances into, out of or within a mitochondrion.
neuron projection maintenance The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3SYS9 KIFBP KIF-binding protein Bos taurus (Bovine) PR
Q96EK5 KIFBP KIF-binding protein Homo sapiens (Human) PR
Q6ZPU9 Kifbp KIF-binding protein Mus musculus (Mouse) PR
10 20 30 40 50 60
MADDWRQVCE TYRRAITLSD VESKNDPENE PYRSKYRARE LLREVRVLLC PEEEEESEAE
70 80 90 100 110 120
GKEERRDGPE SGGRRGESGE LLAARLAVVE FRLGLNHTET EEMSAGEEHL VKSGRIMERF
130 140 150 160 170 180
RLSEEGVSVY IQAQNNLGIL WADRGEIRVA QRYLESAESL YYQYMKEIGK PAIDPDEHFF
190 200 210 220 230 240
SEEQKLTEQE RTKRFERVYT HTLYYLAQVY KHLKQDEKAA QYCHTTLQRQ LEYDSYNPVE
250 260 270 280 290 300
WAINAATLSQ YYVTKQCYME SRHCLAAANV IFSKAEQIPS AEAAKENEAE QERLDLLRQK
310 320 330 340 350 360
KAEIARCWVK YCLNLLQDAR KKLEDNIGEL DVDIQEELKA QRQKEEDEKE KDRKKAILFG
370 380 390 400 410 420
SSDIYDSVQA AEEKVECSHP LDFKEAREVF LVGQNYINES KEYFQLDGHV TDHIEIIQDH
430 440 450 460 470 480
SSLFKLLAFF EEDYERRCKM HKRRIDMLEP LCKELNPQYY LLICRQLQFE LADTSYEMMD
490 500 510 520 530 540
LKVAIGNKLD EMDTHTIKKI NSLAQTAIKY YEMFLDSLRS PDQKFPEKLE EDVLRPAMVA
550 560 570 580 590 600
KFRIARLYGK LISTDGKIQL ENIQKSLNNY KYIVDYCEIN KEAIKCIETE LELSKEMVAL
610
LPTRMERLRI QLASFS