AiPD: Autoinhibited Protein Database

Gene name	ASHR3 (SDG4, SET4, SML, At4g30860, F6I18.230)
Protein name	Histone-lysine N-methyltransferase ASHR3
Names	ASH1-related protein 3, Protein SET DOMAIN GROUP 4, Protein stamen loss
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT4G30860
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-70 (Predicted disordered autoinhibitory region) PR

1-70 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q949T8-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_4_15024703_C_T	53	P>L	No	1000Genomes
ENSVATH06805168	69	A>G	No	1000Genomes
ENSVATH00545876	96	R>K	No	1000Genomes
ENSVATH12325762	105	S>P	No	1000Genomes
tmp_4_15024865_G_A	107	C>Y	No	1000Genomes
ENSVATH12325786	130	P>L	No	1000Genomes
ENSVATH12325786	130	P>R	No	1000Genomes
ENSVATH06805171	130	P>S	No	1000Genomes
tmp_4_15025289_A_T	145	Y>F	No	1000Genomes
ENSVATH02945791	179	R>Q	No	1000Genomes
ENSVATH12325788	179	R>W	No	1000Genomes
tmp_4_15025703_C_A	200	H>N	No	1000Genomes
ENSVATH12325789	202	K>E	No	1000Genomes
ENSVATH06805175	203	D>N	No	1000Genomes
ENSVATH06805176	221	T>S	No	1000Genomes
tmp_4_15025904_A_T	230	I>F	No	1000Genomes
tmp_4_15026117_T_C	242	V>A	No	1000Genomes
tmp_4_15026143_G_A	251	A>T	No	1000Genomes
ENSVATH02945794	255	S>Y	No	1000Genomes
tmp_4_15026375_A_G	295	D>G	No	1000Genomes
tmp_4_15026557_A_G	327	K>R	No	1000Genomes
ENSVATH02945799	350	D>N	No	1000Genomes
ENSVATH06805183	351	F>S	No	1000Genomes
ENSVATH12325827	430	R>C	No	1000Genomes
ENSVATH06805189	450	E>K	No	1000Genomes
ENSVATH14318037	471	P>R	No	1000Genomes
tmp_4_15027344_C_T	471	P>S	No	1000Genomes
ENSVATH02945803	494	P>R	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Endonuclease/exonuclease/phosphatase	5 - 303	IPR005135
domain	Zinc finger, GRF-type	465 - 516	IPR010666
binding_site	AP endonuclease 1, binding site	40 - 49	IPR020847

		Description
EC Number
Subcellular Localization	Nucleus Chromosome	Associated to the euchromatin
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
chromatin	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
histone methyltransferase activity (H3-K36 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein.
metal ion binding	Binding to a metal ion.

Name	Definition
chromatin organization	The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.
regulation of DNA-templated transcription	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9T0G7	SUVH9	Histone-lysine N-methyltransferase family member SUVH9	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9C5P0	SUVH8	Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH8	Arabidopsis thaliana (Mouse-ear cress)	PR