AiPD: Autoinhibited Protein Database

Gene name	Chst15 (Brag, Galnac4s6st, Kiaa0598)
Protein name	Carbohydrate sulfotransferase 15
Names	B-cell RAG-associated gene protein, N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, GalNAc4S-6ST
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:77590
EC number	2.8.2.33: Sulfotransferases
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-59 (Predicted disordered autoinhibitory region) PR

1-59 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q91XQ5-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3388950813	9	V>I	No	EVA
rs3388956553	12	F>L	No	EVA
rs3388950893	14	E>D	No	EVA
rs3388957349	15	D>G	No	EVA
rs3388958360	16	T>A	No	EVA
rs3388910623	18	K>I	No	EVA
rs3388952778	30	S>G	No	EVA
rs3398664465	35	P>L	No	EVA
rs3398564844	56	A>T	No	EVA
rs3388910633	66	E>K	No	EVA
rs3388958974	69	G>D	No	EVA
rs3388957327	70	G>E	No	EVA
rs13473827	72	L>W	No	EVA
rs3388957377	75	R>K	No	EVA
rs3388952541	78	K>M	No	EVA
rs3388953878	82	L>M	No	EVA
rs3388933204	87	I>L	No	EVA
rs3388952791	88	I>L	No	EVA
rs3388933196	127	N>T	No	EVA
rs582161080	128	P>L	No	EVA
rs13473824	137	Q>H	No	EVA
rs3398144735	162	R>W	No	EVA
rs3398564890	163	I>F	No	EVA
rs3398158345	165	F>L	No	EVA
rs3398581474	167	T>S	No	EVA
rs3398672611	168	R>W	No	EVA
rs3388952539	210	T>S	No	EVA
rs3388952784	214	L>V	No	EVA
rs3388943208	227	S>F	No	EVA
rs3388950865	266	T>N	No	EVA
rs3388910597	273	L>I	No	EVA
rs3388933227	278	E>D	No	EVA
rs3388937106	308	Y>N	No	EVA
rs3388943214	310	V>M	No	EVA
rs3388958413	357	A>V	No	EVA
rs3388956580	419	V>M	No	EVA
rs3388953812	420	T>S	No	EVA
rs3388958383	428	N>Y	No	EVA
rs3388952601	432	D>E	No	EVA
rs3388959022	464	W>*	No	EVA
rs3388948826	472	Q>L	No	EVA
rs3398317639	495	F>I	No	EVA
rs3388950881	510	T>I	No	EVA
rs3398158332	537	R>G	No	EVA

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q91XQ5

		Description
EC Number	2.8.2.33	Sulfotransferases
Subcellular Localization	Golgi apparatus membrane ; Single-pass type II membrane protein	A small fraction may also be present at the cell surface, where it acts as a B-cell receptor
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
Golgi membrane	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

Name	Definition
3'-phosphoadenosine 5'-phosphosulfate binding	Binding to 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.

Name	Definition
hexose biosynthetic process	The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q7LFX5	CHST15	Carbohydrate sulfotransferase 15	Homo sapiens (Human)	PR
Q8CHI9	Chst15	Carbohydrate sulfotransferase 15	Rattus norvegicus (Rat)	PR