Q8SPF8

PR
Gene name
BPIFB1 (LPLUNC1)
Protein name
BPI fold-containing family B member 1
Names
Long palate, lung and nasal epithelium carcinoma-associated protein 1, von Ebner minor salivary gland protein, VEMSGP
Species
Bos taurus (Bovine)
KEGG Pathway
bta:282643
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

16-92 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8SPF8

Entry ID Method Resolution Chain Position Source
AF-Q8SPF8-F1 Predicted AlphaFoldDB

No variants for Q8SPF8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8SPF8

No associated diseases with Q8SPF8

2 regional properties for Q8SPF8

Type Name Position InterPro Accession
domain Lipid-binding serum glycoprotein, C-terminal 337 - 468 IPR001124
domain Lipid-binding serum glycoprotein, N-terminal 36 - 255 IPR017942

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

2 GO annotations of biological process

Name Definition
innate immune response in mucosa Any process of the innate immune response that takes place in the mucosal tissues.
negative regulation of toll-like receptor 4 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8NFQ5 BPIFB6 BPI fold-containing family B member 6 Homo sapiens (Human) PR
Q8C186 Bpifc BPI fold-containing family C protein Mus musculus (Mouse) PR
Q93796 nrf-5 Nose resistant to fluoxetine protein 5 Caenorhabditis elegans PR
10 20 30 40 50 60
MAYPWTFTFL CGLLAANLVG ATLSPPVVLS LSTEVIKQML AQKLKNHDVT NTLQQLPLLT
70 80 90 100 110 120
AMEEESSRGI FGNLVKSILK HILWMKVTSA SIGQLQVQPL ANGRQLMVKA PLDVVAGFNV
130 140 150 160 170 180
PLFKTVVELH VEVEAQAIIH VETREKDHAR LVLSECSNTG GSLRVSLLHK LSFLLKCLAD
190 200 210 220 230 240
KVISLLTPAP PKLVKSELCP VLKAGFEDMR GELLNLTKVP MSLNSEHLKL DFISPVIDHS
250 260 270 280 290 300
VVHLILGARL FNSEGKVTKL FNVAGDSLNL PTLNQTPFRL TVRKDVVVAI IAALIHSGKL
310 320 330 340 350 360
TVLLDYVLPE VARQLRSSIK VIDETAAAQL GPTQIVKIMS QTTPMLILDQ GNAKVAQLIV
370 380 390 400 410 420
LEIFATDKDS RPLFTLGIEA SSDIQFYVED GLLVFSFNEI RADRIHLMNS DIGVFNPKLL
430 440 450 460 470
NNITTKILTS ILLPNENGKL RSGIPVSMVK NLGFKSISLS LTKEALVVTQ ASS