Q8C186

PR
Gene name
Bpifc (Bpil2)
Protein name
BPI fold-containing family C protein
Names
Bactericidal/permeability-increasing protein-like 2
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:270757
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

452-509 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8C186

Entry ID Method Resolution Chain Position Source
AF-Q8C186-F1 Predicted AlphaFoldDB

No variants for Q8C186

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8C186

No associated diseases with Q8C186

3 regional properties for Q8C186

Type Name Position InterPro Accession
domain Lipid-binding serum glycoprotein, C-terminal 244 - 480 IPR001124
domain Lipid-binding serum glycoprotein, N-terminal 33 - 259 IPR017942
conserved_site Lipid-binding serum glycoprotein, conserved site 28 - 60 IPR017954

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8SPF8 BPIFB1 BPI fold-containing family B member 1 Bos taurus (Bovine) PR
Q8NFQ5 BPIFB6 BPI fold-containing family B member 6 Homo sapiens (Human) PR
Q93796 nrf-5 Nose resistant to fluoxetine protein 5 Caenorhabditis elegans PR
10 20 30 40 50 60
MRTKQVPVLW ACFLLWSLYI ASSQTVYPGI TARITQRALD YGLQVGMKVL EQLAKEIVIP
70 80 90 100 110 120
DLNGSESLKF LKIDYVKYNF SNIKINAFSF PNTSLAFVPG VGIRALSNHG TANISTNWSV
130 140 150 160 170 180
KAPLFRDSGA ANLFLSGIYF TGIVAFTRND FGYPALELQD CHVQVSHARV SFFGSLSALY
190 200 210 220 230 240
NSFAEPMEKP ILKNLNEMVQ LCPIAISQVE QFNVNISALE VLTKIDNYTV LDCSLISPPE
250 260 270 280 290 300
ITENHLDFNL KGAFYPLESL VDPPFTPAPF HLPESRDSML YIGISEYFFK SASFAHYVSG
310 320 330 340 350 360
ALGTTLSTRE ISNYFSQNVQ GFGSVLSKIA EIYVLSQPFI LQMMATGPPM VNLQRNNFSL
370 380 390 400 410 420
EFPAAVIMLT QLDNSTIQPI VSMDFVASTS VGLAILGQKL ICSLSLNRFR LSLPENSQRD
430 440 450 460 470 480
AKVVRFENIL SSILHFGVLP LANTKLQQGF PLPNPYNISF INSDIEVLEG YLLVSSDLAY
490 500
DTSSKPQPNL NSWGDLNLVH RPWREQPTH