Q8S3F1
Gene name |
NAI1 (BHLH20, EN27, At2g22770, T30L20.3) |
Protein name |
Transcription factor NAI1 |
Names |
Basic helix-loop-helix protein 20, AtbHLH20, bHLH 20, Transcription factor EN 27, bHLH transcription factor bHLH020 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G22770 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8S3F1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8S3F1-F1 | Predicted | AlphaFoldDB |
22 variants for Q8S3F1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05559559 | 3 | D>E | No | 1000Genomes | |
| tmp_2_9684891_G_A | 12 | D>N | No | 1000Genomes | |
| ENSVATH05559560 | 48 | L>R | No | 1000Genomes | |
| tmp_2_9685025_G_A | 56 | M>I | No | 1000Genomes | |
| ENSVATH05559561 | 62 | M>T | No | 1000Genomes | |
| tmp_2_9685050_A_G | 65 | T>A | No | 1000Genomes | |
| ENSVATH14534082 | 69 | P>L | No | 1000Genomes | |
| tmp_2_9685128_A_G | 91 | K>E | No | 1000Genomes | |
| tmp_2_9685178_G_T | 107 | M>I | No | 1000Genomes | |
| ENSVATH05559563 | 125 | R>K | No | 1000Genomes | |
| ENSVATH13335638 | 173 | H>Y | No | 1000Genomes | |
| tmp_2_9685882_C_T | 213 | S>L | No | 1000Genomes | |
| tmp_2_9685884_T_G | 214 | S>A | No | 1000Genomes | |
| tmp_2_9685897_C_A | 218 | T>N | No | 1000Genomes | |
| tmp_2_9685903_C_T | 220 | S>F | No | 1000Genomes | |
| tmp_2_9686024_C_G | 260 | N>K | No | 1000Genomes | |
| ENSVATH05559575 | 270 | S>F | No | 1000Genomes | |
| ENSVATH05559575 | 270 | S>Y | No | 1000Genomes | |
| tmp_2_9686067_C_T | 275 | R>C | No | 1000Genomes | |
| ENSVATH14534088 | 301 | N>Y | No | 1000Genomes | |
| ENSVATH05559580 | 310 | V>L | No | 1000Genomes | |
| tmp_2_9686304_G_A | 316 | V>I | No | 1000Genomes |
No associated diseases with Q8S3F1
1 regional properties for Q8S3F1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Myc-type, basic helix-loop-helix (bHLH) domain | 128 - 183 | IPR011598 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| protein dimerization activity | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| endoplasmic reticulum organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDDSSFMDLM | IDTDEYLIDD | WESDFPICGE | TNTNPGSESG | SGTGFELLAE | RPTKQMKTNN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NMNSTSSSPS | SSSSSGSRTS | QVISFGSPDT | KTNPVETSLN | FSNQVSMDQK | VGSKRKDCVN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NGGRREPHLL | KEHVLAERKR | RQKLNERLIA | LSALLPGLKK | TDKATVLEDA | IKHLKQLQER |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VKKLEEERVV | TKKMDQSIIL | VKRSQVYLDD | DSSSYSSTCS | AASPLSSSSD | EVSIFKQTMP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MIEARVSDRD | LLIRVHCEKN | KGCMIKILSS | LEKFRLEVVN | SFTLPFGNST | LVITILTKMD |
| 310 | |||||
| NKFSRPVEEV | VKNIRVALAE |