Q8RY60
Gene name |
CBSDUF7 (At1g47330, T3F24.6) |
Protein name |
DUF21 domain-containing protein At1g47330 |
Names |
CBS domain-containing protein CBSDUF7 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G47330 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8RY60
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8RY60-F1 | Predicted | AlphaFoldDB |
33 variants for Q8RY60
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04886719 | 2 | S>P | No | 1000Genomes | |
| ENSVATH13403507 | 5 | I>V | No | 1000Genomes | |
| tmp_1_17351218_G_A | 24 | A>T | No | 1000Genomes | |
| ENSVATH01304638 | 40 | G>S | No | 1000Genomes | |
| ENSVATH04886721 | 52 | R>L | No | 1000Genomes | |
| tmp_1_17352325_C_T | 205 | T>M | No | 1000Genomes | |
| ENSVATH04886736 | 212 | P>S | No | 1000Genomes | |
| tmp_1_17352382_C_T | 224 | P>L | No | 1000Genomes | |
| ENSVATH01304680 | 229 | T>I | No | 1000Genomes | |
| tmp_1_17352541_G_A | 243 | V>I | No | 1000Genomes | |
| tmp_1_17352556_C_T | 248 | P>S | No | 1000Genomes | |
| tmp_1_17352834_G_C | 284 | E>D | No | 1000Genomes | |
| tmp_1_17352907_C_T | 309 | L>F | No | 1000Genomes | |
| ENSVATH04886747 | 314 | Q>R | No | 1000Genomes | |
| tmp_1_17352925_T_A | 315 | S>T | No | 1000Genomes | |
| ENSVATH01304698 | 327 | K>E | No | 1000Genomes | |
| ENSVATH01304698 | 327 | K>Q | No | 1000Genomes | |
| ENSVATH14242570 | 327 | K>R | No | 1000Genomes | |
| ENSVATH13403553 | 361 | D>E | No | 1000Genomes | |
| tmp_1_17353177_A_G | 372 | E>G | No | 1000Genomes | |
| tmp_1_17353260_A_G | 400 | I>V | No | 1000Genomes | |
| ENSVATH04886750 | 401 | E>G | No | 1000Genomes | |
| tmp_1_17353506_C_T | 451 | H>Y | No | 1000Genomes | |
| ENSVATH01304710 | 489 | T>I | No | 1000Genomes | |
| ENSVATH01304713 | 499 | K>N | No | 1000Genomes | |
| tmp_1_17353659_G_C | 502 | V>L | No | 1000Genomes | |
| ENSVATH13403576 | 505 | P>S | No | 1000Genomes | |
| ENSVATH01304714 | 511 | D>E | No | 1000Genomes | |
| ENSVATH13403577 | 513 | S>L | No | 1000Genomes | |
| ENSVATH00083181 | 518 | P>S | No | 1000Genomes | |
| ENSVATH00083182 | 522 | E>A | No | 1000Genomes | |
| tmp_1_17353726_C_T | 524 | T>I | No | 1000Genomes | |
| ENSVATH13403578 | 528 | L>R | No | 1000Genomes |
No associated diseases with Q8RY60
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| magnesium ion homeostasis | Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q6P4Q7 | CNNM4 | Metal transporter CNNM4 | Homo sapiens (Human) | PR |
| Q8NE01 | CNNM3 | Metal transporter CNNM3 | Homo sapiens (Human) | PR |
| Q9H8M5 | CNNM2 | Metal transporter CNNM2 | Homo sapiens (Human) | PR |
| Q69ZF7 | Cnnm4 | Metal transporter CNNM4 | Mus musculus (Mouse) | PR |
| Q3TWN3 | Cnnm2 | Metal transporter CNNM2 | Mus musculus (Mouse) | PR |
| P0C588 | Cnnm4 | Metal transporter CNNM4 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSDIPCCGT | TFSLYVVIII | ALVAFAGLMA | GLTLGLMSLG | LVDLEVLIKS | GRPQDRINAG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KIFPVVKNQH | LLLCTLLIGN | SMAMEALPIF | LDKIVPPWLA | ILLSVTLILV | FGEIMPQAVC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TRYGLKVGAI | MAPFVRVLLV | LFFPISYPIS | KVLDWMLGKG | HGVLLRRAEL | KTFVNFHGNE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AGKGGDLTTD | ETSIITGALE | LTEKTAKDAM | TPISNAFSLE | LDTPLNLETL | NTIMSVGHSR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VPVYFRNPTH | IIGLILVKNL | LAVDARKEVP | LRKMSMRKIP | RVSETMPLYD | ILNEFQKGHS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HIAVVYKDLD | EQEQSPETSE | NGIERRKNKK | TKDELFKDSC | RKPKAQFEVS | EKEVFKIETG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DAKSGKSENG | EEQQGSGKTS | LLAAPAKKRH | RGCSFCILDI | ENTPIPDFPT | NEEVVGVITM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EDVIEELLQE | EILDETDEYV | NIHNRIRVNM | HASPENLPSV | ITSITQSSSG | STSPNQTSHM |
| 490 | 500 | 510 | 520 | ||
| ATPDSSPTTK | PSNSSPTRKP | SVSSPTREPS | DSSHSMAPKH | EESTQTL |