Q8N4G2
SS
Gene name |
ARL14 (ARF7) |
Protein name |
ADP-ribosylation factor-like protein 14 |
Names |
ADP-ribosylation factor 7 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:80117 |
EC number |
|
Protein Class |
|
Descriptions
Small GTPases couple their GDP/GTP structural cycle to cytosol/membrane alternation to function as versatile molecular switches in the cell. Membrane localization of their active, GTP-bound form is pivotal to their ability to propagate information, and this requires their post-translational modification by lipids.<br>Arf GTPases are modified by a myristate attached to their N-terminus, which is shielded by intramolecular interactions in their inactive state. The myristoylated N-terminus of Arf is autoinhibitory in solution and is displaced by membranes, priming Arf GTPases for activation by their GEFs. Replacement of the N-terminal myristate by a 6xHis-tag preserves autoinhibition, representing that membranes unlock the N-terminal region to facilitate subsequent activation.
Autoinhibitory domains (AIDs)
Target domain |
16-139 (Small GTP-binding protein domain) |
Relief mechanism |
Ligand binding |
Assay |
|
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8N4G2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8N4G2-F1 | Predicted | AlphaFoldDB |
247 variants for Q8N4G2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs1461146527 | 2 | G>C | No |
TOPMed gnomAD |
|
| rs146704564 | 2 | G>V | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs139090920 | 3 | S>L | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs2108025183 | 3 | S>P | No | Ensembl | |
| rs548220537 | 4 | L>M | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs760863756 | 4 | L>P | No |
ExAC TOPMed gnomAD |
|
| rs764074683 | 5 | G>D | No |
ExAC TOPMed gnomAD |
|
| rs754095868 | 9 | P>L | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
ExAC NCI-TCGA TOPMed gnomAD |
| rs754095868 | 9 | P>R | No |
ExAC TOPMed gnomAD |
|
| rs1468058604 | 10 | Q>H | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
NCI-TCGA gnomAD |
| rs751320155 | 10 | Q>R | No | ExAC | |
| rs1713262426 | 11 | T>N | No | Ensembl | |
| rs1047454023 | 12 | K>R | No |
TOPMed gnomAD |
|
| rs1047454023 | 12 | K>T | No |
TOPMed gnomAD |
|
| COSM4929980 | 13 | Q>* | Variant assessed as Somatic; HIGH impact. [NCI-TCGA] | No | NCI-TCGA Cosmic |
| rs781128689 | 14 | A>S | No |
ExAC TOPMed gnomAD |
|
| rs781128689 | 14 | A>T | No |
ExAC TOPMed gnomAD |
|
| rs1444468942 | 14 | A>V | No | Ensembl | |
| rs748023818 | 15 | Q>R | No |
ExAC gnomAD |
|
| rs1560081618 | 16 | V>I | No | TOPMed | |
| rs1327680252 | 17 | L>P | No |
TOPMed gnomAD |
|
| COSM1040646 | 18 | L>I | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No | NCI-TCGA Cosmic |
| TCGA novel | 18 | L>P | Variant assessed as Somatic; HIGH impact. [NCI-TCGA] | No | NCI-TCGA |
| rs755718463 | 18 | L>R | No |
ExAC gnomAD |
|
| rs1713263534 | 19 | L>S | No | gnomAD | |
|
rs748999128 COSM5736813 |
20 | G>E | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
NCI-TCGA Cosmic ExAC NCI-TCGA gnomAD |
| rs777386557 | 20 | G>R | No |
ExAC gnomAD |
|
| rs1713263951 | 21 | L>F | No | gnomAD | |
| rs774859720 | 21 | L>P | No |
ExAC gnomAD |
|
| rs199795781 | 22 | D>H | No |
1000Genomes ExAC |
|
| rs557175663 | 24 | A>D | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs201732930 | 25 | G>E | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs146619115 | 25 | G>R | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs146619115 | 25 | G>W | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs200111812 | 26 | K>* | No | gnomAD | |
| rs200111812 | 26 | K>E | No | gnomAD | |
| rs774047450 | 26 | K>N | No |
ExAC TOPMed gnomAD |
|
| rs764279237 | 26 | K>R | No |
ExAC gnomAD |
|
| rs762057724 | 27 | S>P | No |
ExAC gnomAD |
|
| rs765380940 | 28 | T>A | No |
ExAC TOPMed |
|
| rs751371454 | 28 | T>I | No |
ExAC gnomAD |
|
| rs765380940 | 28 | T>P | No |
ExAC TOPMed |
|
| rs2108025246 | 29 | L>P | No | Ensembl | |
| rs767213992 | 31 | Y>F | No |
ExAC TOPMed gnomAD |
|
| rs1452693806 | 31 | Y>H | No | gnomAD | |
| rs752720930 | 32 | K>E | No |
ExAC gnomAD |
|
| rs1713265825 | 34 | K>N | No | TOPMed | |
| rs370792201 | 35 | L>F | No |
ESP TOPMed gnomAD |
|
| rs1403612347 | 38 | D>N | No | gnomAD | |
| rs777455458 | 40 | T>A | No |
ExAC gnomAD |
|
| rs748739938 | 40 | T>N | No |
ExAC gnomAD |
|
| rs761826350 | 41 | T>I | No |
ExAC TOPMed gnomAD |
|
| rs761826350 | 41 | T>S | No |
ExAC TOPMed gnomAD |
|
| rs151085412 | 42 | I>N | No |
ESP ExAC TOPMed gnomAD |
|
| rs187614470 | 43 | P>S | No |
1000Genomes ESP ExAC gnomAD |
|
| rs772811944 | 44 | T>I | No | Ensembl | |
| TCGA novel | 45 | I>L | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No | NCI-TCGA |
| rs772524730 | 45 | I>T | No |
ExAC TOPMed gnomAD |
|
| rs760529385 | 45 | I>V | No |
TOPMed gnomAD |
|
| rs1713266855 | 46 | G>D | No | TOPMed | |
| rs775691418 | 46 | G>S | No |
ExAC gnomAD |
|
| rs747570888 | 47 | F>L | No |
ExAC TOPMed gnomAD |
|
| rs1713267063 | 48 | N>S | No |
TOPMed gnomAD |
|
| rs200837427 | 49 | V>M | No |
1000Genomes ExAC gnomAD |
|
| rs1179331816 | 51 | M>L | No | gnomAD | |
| rs533454381 | 51 | M>R | No | Ensembl | |
| rs573150490 | 53 | E>* | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1397078039 | 53 | E>D | No | TOPMed | |
| rs573150490 | 53 | E>K | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1162427800 | 56 | R>S | No |
TOPMed gnomAD |
|
| rs17853289 | 58 | L>F | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
Ensembl NCI-TCGA |
| rs146546740 | 60 | L>F | No |
ESP ExAC TOPMed gnomAD |
|
| rs1713268375 | 61 | T>R | No | Ensembl | |
| rs767395235 | 62 | V>F | No |
ExAC TOPMed gnomAD |
|
| rs767395235 | 62 | V>L | No |
ExAC TOPMed gnomAD |
|
| rs914690092 | 63 | W>* | No | Ensembl | |
| rs1481235826 | 63 | W>R | No |
TOPMed gnomAD |
|
| rs913306835 | 64 | D>E | No | TOPMed | |
| rs1713269315 | 64 | D>V | No | TOPMed | |
| rs969244931 | 65 | V>A | No | TOPMed | |
| rs1560081745 | 66 | G>A | No | Ensembl | |
| rs1713269640 | 67 | G>E | No |
TOPMed gnomAD |
|
| rs1392021193 | 67 | G>R | No | gnomAD | |
| rs1713269790 | 68 | Q>R | No | Ensembl | |
| rs1416634459 | 69 | E>* | No |
TOPMed gnomAD |
|
| rs1713270113 | 69 | E>A | No | Ensembl | |
| rs1713270383 | 70 | K>E | No | Ensembl | |
| COSM4449335 | 71 | M>* | Variant assessed as Somatic; HIGH impact. [NCI-TCGA] | No | NCI-TCGA Cosmic |
| rs1713270551 | 71 | M>I | No | Ensembl | |
| rs760666218 | 72 | R>I | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
ExAC NCI-TCGA gnomAD |
| rs750581360 | 73 | T>A | No |
ExAC TOPMed gnomAD |
|
| rs1553797372 | 73 | T>I | No | Ensembl | |
| rs750581360 | 73 | T>P | No |
ExAC TOPMed gnomAD |
|
| rs753812333 | 74 | V>G | No |
ExAC TOPMed gnomAD |
|
| rs778531724 | 75 | W>* | No |
ExAC TOPMed gnomAD |
|
| rs750136438 | 75 | W>* | No |
ExAC TOPMed gnomAD |
|
| rs756894023 | 75 | W>G | No |
ExAC gnomAD |
|
| rs757934795 | 76 | G>S | No |
ExAC gnomAD |
|
| rs780494931 | 76 | G>V | No |
ExAC gnomAD |
|
| rs762555229 | 77 | C>R | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
NCI-TCGA TOPMed gnomAD |
| rs769169425 | 78 | Y>* | No |
ExAC gnomAD |
|
| rs747273775 | 78 | Y>C | No |
ExAC TOPMed gnomAD |
|
| rs2108025365 | 79 | C>W | No | Ensembl | |
| rs1182590662 | 79 | C>Y | No | gnomAD | |
| rs781709360 | 80 | E>D | No |
ExAC gnomAD |
|
| rs1382935026 | 80 | E>G | No | gnomAD | |
| rs923449097 | 81 | N>T | No |
TOPMed gnomAD |
|
| rs748652938 | 82 | T>N | No |
ExAC TOPMed gnomAD |
|
| rs763260093 | 83 | D>E | No |
ExAC TOPMed gnomAD |
|
|
rs35634980 VAR_055521 |
83 | D>N | No |
UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
| rs35634980 | 83 | D>Y | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs1713274026 | 86 | V>A | No | gnomAD | |
| rs770991598 | 86 | V>L | No |
ExAC gnomAD |
|
| rs760603451 | 87 | Y>* | No |
ExAC TOPMed gnomAD |
|
| rs1186401848 | 87 | Y>C | No |
TOPMed gnomAD |
|
| rs1713274340 | 87 | Y>H | No | Ensembl | |
| rs369705585 | 88 | V>A | No |
1000Genomes TOPMed gnomAD |
|
| rs1380789536 | 88 | V>I | No |
TOPMed gnomAD |
|
| COSM1308777 | 90 | D>N | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No | NCI-TCGA Cosmic |
| rs1486950377 | 90 | D>V | No |
TOPMed gnomAD |
|
| rs898272129 | 91 | S>G | No | Ensembl | |
| rs1713275277 | 92 | T>R | No | Ensembl | |
| rs368653565 | 93 | D>E | No |
ESP ExAC TOPMed gnomAD |
|
| rs373695187 | 93 | D>G | No |
ESP ExAC TOPMed gnomAD |
|
| COSM1040648 | 93 | D>Y | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No | NCI-TCGA Cosmic |
| rs1713275610 | 95 | Q>R | No | TOPMed | |
| rs180925087 | 96 | R>* | Variant assessed as Somatic; HIGH impact. [NCI-TCGA] | No |
1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
| rs749857278 | 96 | R>L | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
ExAC NCI-TCGA gnomAD |
| rs749857278 | 96 | R>P | No |
ExAC gnomAD |
|
| rs749857278 | 96 | R>Q | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
ExAC NCI-TCGA gnomAD |
| rs1713276156 | 99 | E>G | No | TOPMed | |
| rs751214251 | 101 | Q>* | No |
ExAC gnomAD |
|
| rs1317014531 | 103 | Q>E | No |
TOPMed gnomAD |
|
| rs1484011600 | 103 | Q>H | No |
TOPMed gnomAD |
|
| rs766462181 | 103 | Q>R | No | gnomAD | |
| rs1257643476 | 104 | F>S | No |
TOPMed gnomAD |
|
| rs2108025426 | 105 | E>K | No | Ensembl | |
| rs1357362369 | 106 | H>R | No | TOPMed | |
| rs1713276758 | 106 | H>Y | No | TOPMed | |
| rs755405660 | 107 | I>V | No |
ExAC gnomAD |
|
| rs781506659 | 108 | L>S | No |
ExAC gnomAD |
|
| rs1713277183 | 109 | K>E | No | Ensembl | |
| rs551845257 | 109 | K>N | No | gnomAD | |
| rs748705792 | 110 | N>K | No |
ExAC TOPMed gnomAD |
|
| COSM1040649 | 111 | E>D | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No | NCI-TCGA Cosmic |
| rs770237114 | 113 | I>V | No |
ExAC gnomAD |
|
| rs777940452 | 114 | K>T | No |
ExAC gnomAD |
|
| rs749268590 | 115 | N>K | No |
ExAC TOPMed gnomAD |
|
| TCGA novel | 115 | N>M | Variant assessed as Somatic; HIGH impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1176109655 | 115 | N>S | No | gnomAD | |
| rs35633732 | 117 | P>A | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs35633732 | 117 | P>S | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
|
VAR_055522 rs35633732 |
117 | P>T | No |
UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
| rs759799025 | 118 | V>A | No |
ExAC TOPMed gnomAD |
|
| rs1367937808 | 118 | V>I | No |
TOPMed gnomAD |
|
| rs1380533085 | 119 | V>F | No |
TOPMed gnomAD |
|
| COSM1420333 | 119 | V>I | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No | NCI-TCGA Cosmic |
| rs1222713117 | 124 | K>I | No | gnomAD | |
| rs1713279805 | 124 | K>N | No | TOPMed | |
| rs1445670373 | 125 | Q>* | No |
TOPMed gnomAD |
|
| rs775873693 | 126 | D>CE* | No | ExAC | |
| rs1713280544 | 127 | M>I | No | gnomAD | |
| rs560623020 | 127 | M>T | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs776515384 | 127 | M>V | No | ExAC | |
| rs370953853 | 128 | P>A | No |
ESP ExAC TOPMed gnomAD |
|
| COSM3915239 | 128 | P>L | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No | NCI-TCGA Cosmic |
| rs370953853 | 128 | P>S | No |
ESP ExAC TOPMed gnomAD |
|
| rs1560081905 | 130 | A>G | No | Ensembl | |
| rs1560081905 | 130 | A>V | No | Ensembl | |
| rs772796463 | 131 | L>P | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
ExAC NCI-TCGA TOPMed gnomAD |
| rs2108025489 | 131 | L>V | No | Ensembl | |
| rs1006387056 | 132 | T>A | No | TOPMed | |
| rs759792947 | 132 | T>I | No |
ExAC TOPMed gnomAD |
|
| rs759792947 | 132 | T>N | No |
ExAC TOPMed gnomAD |
|
| rs754603489 | 133 | A>T | No |
ExAC gnomAD |
|
| rs1478415281 | 134 | E>K | No | gnomAD | |
| rs767893500 | 135 | D>G | No |
ExAC gnomAD |
|
| rs868841725 | 135 | D>N | No | Ensembl | |
| rs866395518 | 136 | I>V | No | TOPMed | |
| rs996409398 | 137 | T>A | No | TOPMed | |
| rs1423484844 | 137 | T>I | No |
TOPMed gnomAD |
|
| rs765276860 | 138 | R>G | No | Ensembl | |
| rs756625995 | 139 | M>I | No |
ExAC gnomAD |
|
| rs148659343 | 140 | F>L | No |
ESP ExAC TOPMed gnomAD |
|
| rs757320842 | 144 | K>N | No |
ExAC TOPMed gnomAD |
|
| rs749797536 | 144 | K>Q | No |
ExAC gnomAD |
|
| rs779025543 | 145 | L>F | No |
ExAC TOPMed gnomAD |
|
| rs779025543 | 145 | L>I | No |
ExAC TOPMed gnomAD |
|
| rs1170625323 | 147 | S>R | No | TOPMed | |
| rs201138551 | 149 | R>G | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs200165371 | 149 | R>Q | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs201138551 | 149 | R>W | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs776570079 | 150 | N>D | No |
ExAC gnomAD |
|
| rs747897062 | 151 | W>S | No |
ExAC TOPMed gnomAD |
|
| rs769619944 | 152 | Y>S | No |
ExAC TOPMed gnomAD |
|
| rs1192088824 | 153 | V>A | No |
TOPMed gnomAD |
|
| rs1479215839 | 153 | V>M | No | gnomAD | |
| rs773095286 | 154 | Q>P | No |
ExAC TOPMed gnomAD |
|
| rs773095286 | 154 | Q>R | No |
ExAC TOPMed gnomAD |
|
| rs1577095937 | 155 | P>L | No | gnomAD | |
| rs1577095937 | 155 | P>R | No | gnomAD | |
| rs201785407 | 155 | P>S | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs201785407 | 155 | P>T | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1295896239 | 157 | C>S | No |
TOPMed gnomAD |
|
| rs1713286353 | 158 | A>V | No | gnomAD | |
| rs1713286521 | 159 | L>I | No | Ensembl | |
| rs1424025451 | 160 | T>A | No |
TOPMed gnomAD |
|
| rs1424025451 | 160 | T>P | No |
TOPMed gnomAD |
|
| rs759219063 | 161 | G>E | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
ExAC NCI-TCGA TOPMed gnomAD |
| rs1374253896 | 162 | E>D | No |
TOPMed gnomAD |
|
| rs2108025577 | 162 | E>G | No | Ensembl | |
| rs550741923 | 162 | E>K | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs139209499 | 163 | G>E | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs146210673 | 163 | G>R | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs139209499 | 163 | G>V | No |
1000Genomes ESP ExAC TOPMed gnomAD |
|
| rs754350494 | 165 | A>T | No |
ExAC TOPMed gnomAD |
|
| rs1288374154 | 165 | A>V | No | gnomAD | |
|
COSM729409 rs1453792966 |
166 | Q>* | lung [Cosmic] | No |
cosmic curated gnomAD |
| rs553187876 | 167 | G>A | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs553187876 | 167 | G>V | No |
1000Genomes ExAC TOPMed gnomAD |
|
| rs1560082008 | 168 | F>L | No | Ensembl | |
| rs1168795849 | 168 | F>S | No | TOPMed | |
| rs1577095974 | 168 | F>V | No | Ensembl | |
| rs1713288395 | 169 | R>G | No | Ensembl | |
| rs1394056850 | 173 | G>E | Variant assessed as Somatic; MODERATE impact. [NCI-TCGA] | No |
NCI-TCGA TOPMed gnomAD |
| rs780483810 | 174 | F>S | No |
ExAC TOPMed gnomAD |
|
| rs1444111152 | 175 | V>L | No | gnomAD | |
| rs1263330168 | 178 | H>P | No |
TOPMed gnomAD |
|
| rs267599666 | 179 | M>I | No |
ExAC TOPMed gnomAD |
|
| rs747233103 | 179 | M>L | No |
ExAC gnomAD |
|
| rs143957388 | 179 | M>T | No |
ESP ExAC TOPMed gnomAD |
|
| rs747233103 | 179 | M>V | No |
ExAC gnomAD |
|
| rs1713289270 | 182 | R>G | No | TOPMed | |
| rs1346915701 | 184 | D>G | No |
TOPMed gnomAD |
|
| rs367959636 | 184 | D>N | No |
ESP TOPMed gnomAD |
|
| rs1397839241 | 185 | T>A | No | gnomAD | |
| rs1713289603 | 186 | L>V | No | gnomAD | |
| rs749205499 | 186 | L>W | No |
ExAC TOPMed gnomAD |
|
| rs200870412 | 187 | A>V | No |
ExAC TOPMed gnomAD |
|
| rs1713290028 | 190 | K>R | No |
TOPMed gnomAD |
|
| rs771563756 | 191 | Q>* | No |
ExAC TOPMed gnomAD |
|
| rs771563756 | 191 | Q>E | No |
ExAC TOPMed gnomAD |
|
| rs566675647 | 191 | Q>H | No |
1000Genomes ExAC gnomAD |
|
| rs764385820 | 192 | N>K | No |
ExAC gnomAD |
|
| rs1257906330 | 193 | N>R | No |
TOPMed gnomAD |
|
| rs907709368 | 193 | N>S | No | TOPMed | |
| rs1330183124 | 193 | N>W | No | TOPMed |
No associated diseases with Q8N4G2
1 regional properties for Q8N4G2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 12 - 134 | IPR005225 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic vesicle | A vesicle found in the cytoplasm of a cell. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
| vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
48 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2KJ96 | ARL5A | ADP-ribosylation factor-like protein 5A | Bos taurus (Bovine) | SS |
| P84081 | ARF2 | ADP-ribosylation factor 2 | Bos taurus (Bovine) | SS |
| P84080 | ARF1 | ADP-ribosylation factor 1 | Bos taurus (Bovine) | SS |
| Q3SZF2 | ARF4 | ADP-ribosylation factor 4 | Bos taurus (Bovine) | SS |
| Q0VC18 | ARL4D | ADP-ribosylation factor-like protein 4D | Bos taurus (Bovine) | PR |
| P49702 | ARF5 | ADP-ribosylation factor 5 | Gallus gallus (Chicken) | SS |
| P40945 | Arf4 | ADP ribosylation factor 4 | Drosophila melanogaster (Fruit fly) | SS |
| P61209 | Arf1 | ADP-ribosylation factor 1 | Drosophila melanogaster (Fruit fly) | SS |
| A6NH57 | ARL5C | Putative ADP-ribosylation factor-like protein 5C | Homo sapiens (Human) | SS |
| P18085 | ARF4 | ADP-ribosylation factor 4 | Homo sapiens (Human) | EV |
| P49703 | ARL4D | ADP-ribosylation factor-like protein 4D | Homo sapiens (Human) | PR |
| P84077 | ARF1 | ADP-ribosylation factor 1 | Homo sapiens (Human) | EV |
| P84085 | ARF5 | ADP-ribosylation factor 5 | Homo sapiens (Human) | EV |
| Q969Q4 | ARL11 | ADP-ribosylation factor-like protein 11 | Homo sapiens (Human) | PR |
| Q96KC2 | ARL5B | ADP-ribosylation factor-like protein 5B | Homo sapiens (Human) | SS |
| P62330 | ARF6 | ADP-ribosylation factor 6 | Homo sapiens (Human) | EV |
| Q8IVW1 | ARL17A | ADP-ribosylation factor-like protein 17 | Homo sapiens (Human) | SS |
| Q9H0F7 | ARL6 | ADP-ribosylation factor-like protein 6 | Homo sapiens (Human) | SS |
| P40616 | ARL1 | ADP-ribosylation factor-like protein 1 | Homo sapiens (Human) | SS |
| P61204 | ARF3 | ADP-ribosylation factor 3 | Homo sapiens (Human) | EV |
| Q9Y689 | ARL5A | ADP-ribosylation factor-like protein 5A | Homo sapiens (Human) | SS |
| P49076 | ARF1 | ADP-ribosylation factor | Zea mays (Maize) | SS |
| P84084 | Arf5 | ADP-ribosylation factor 5 | Mus musculus (Mouse) | SS |
| P61750 | Arf4 | ADP-ribosylation factor 4 | Mus musculus (Mouse) | SS |
| Q99PE9 | Arl4d | ADP-ribosylation factor-like protein 4D | Mus musculus (Mouse) | PR |
| Q6P068 | Arl5c | ADP-ribosylation factor-like protein 5C | Mus musculus (Mouse) | SS |
| Q80ZU0 | Arl5a | ADP-ribosylation factor-like protein 5A | Mus musculus (Mouse) | SS |
| P61205 | Arf3 | ADP-ribosylation factor 3 | Mus musculus (Mouse) | SS |
| Q9D4P0 | Arl5b | ADP-ribosylation factor-like protein 5B | Mus musculus (Mouse) | SS |
| P84078 | Arf1 | ADP-ribosylation factor 1 | Mus musculus (Mouse) | SS |
| Q8BSL7 | Arf2 | ADP-ribosylation factor 2 | Mus musculus (Mouse) | SS |
| P51824 | ADP-ribosylation factor 1 | Solanum tuberosum (Potato) | SS | |
| P84082 | Arf2 | ADP-ribosylation factor 2 | Rattus norvegicus (Rat) | SS |
| P51646 | Arl5a | ADP-ribosylation factor-like protein 5A | Rattus norvegicus (Rat) | SS |
| P84083 | Arf5 | ADP-ribosylation factor 5 | Rattus norvegicus (Rat) | SS |
| P36407 | Trim23 | E3 ubiquitin-protein ligase TRIM23 | Rattus norvegicus (Rat) | SS |
| P61751 | Arf4 | ADP-ribosylation factor 4 | Rattus norvegicus (Rat) | SS |
| P61206 | Arf3 | ADP-ribosylation factor 3 | Rattus norvegicus (Rat) | SS |
| P84079 | Arf1 | ADP-ribosylation factor 1 | Rattus norvegicus (Rat) | SS |
| P51823 | ARF | ADP-ribosylation factor 2 | Oryza sativa subsp. japonica (Rice) | SS |
| Q06396 | Os01g0813400 | ADP-ribosylation factor 1 | Oryza sativa subsp. japonica (Rice) | SS |
| Q10943 | arf-1.2 | ADP-ribosylation factor 1-like 2 | Caenorhabditis elegans | SS |
| P34212 | arl-5 | ADP-ribosylation factor-like protein 5 | Caenorhabditis elegans | SS |
| P40940 | ARF3 | ADP-ribosylation factor 3 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| P36397 | ARF1 | ADP-ribosylation factor 1 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| P0DH91 | ARF2-B | ADP-ribosylation factor 2-B | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9LQC8 | ARF2-A | ADP-ribosylation factor 2-A | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q5M9P8 | arl6 | ADP-ribosylation factor-like protein 6 | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGSLGSKNPQ | TKQAQVLLLG | LDSAGKSTLL | YKLKLAKDIT | TIPTIGFNVE | MIELERNLSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TVWDVGGQEK | MRTVWGCYCE | NTDGLVYVVD | STDKQRLEES | QRQFEHILKN | EHIKNVPVVL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LANKQDMPGA | LTAEDITRMF | KVKKLCSDRN | WYVQPCCALT | GEGLAQGFRK | LTGFVKSHMK |
| 190 | |||||
| SRGDTLAFFK | QN |