AiPD: Autoinhibited Protein Database

Q8N0S6

Gene name	CENPL (C1orf155, ICEN33)
Protein name	Centromere protein L
Names	CENP-L, Interphase centromere complex protein 33
Species	Homo sapiens (Human)
KEGG Pathway	hsa:91687
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-85 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-85 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

9 structures for Q8N0S6

Entry ID	Method	Resolution	Chain	Position	Source
7PKN	EM	320 A	L	1-344	PDB
7QOO	EM	460 A	L	1-344	PDB
7R5S	EM	283 A	L	1-344	PDB
7R5V	EM	455 A	L	1-344	PDB
7XHN	EM	371 A	L	1-344	PDB
7XHO	EM	329 A	L	1-344	PDB
7YWX	EM	1200 A	L	1-344	PDB
7YYH	EM	890 A	L	1-344	PDB
AF-Q8N0S6-F1	Predicted				AlphaFoldDB

237 variants for Q8N0S6

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
TCGA novel	2	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1249949 rs778033095	4	Y>C		No	ClinGen ExAC gnomAD
rs200103202 CA1249947	6	A>V		No	ClinGen ExAC TOPMed gnomAD
rs759355150 CA1249945	9	S>T		No	ClinGen ExAC gnomAD
CA343751953 rs1180569993	10	T>I		No	ClinGen gnomAD
CA32754441 rs768818748	12	S>N		No	ClinGen Ensembl
rs1228713208 CA343751934	13	A>V		No	ClinGen TOPMed
rs1557846752 CA343751926	14	S>F		No	ClinGen Ensembl
CA1249943 rs766067591	15	S>*		No	ClinGen ExAC gnomAD
CA343751918 rs1435824380	16	R>K		No	ClinGen TOPMed gnomAD
CA1249942 rs760560286	16	R>S		No	ClinGen ExAC
CA1249941 rs139971891	17	P>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1489990736 CA343751912	17	P>S		No	ClinGen gnomAD
rs376379173 CA1249940	19	D>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs1571962062 CA343751890	20	Y>C		No	ClinGen Ensembl
CA343751892 rs1179549072	20	Y>N		No	ClinGen TOPMed
rs1557846727 CA343751886	21	F>I		No	ClinGen Ensembl
CA1249939 rs151044818	21	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs952181147 CA32754422	22	I>V		No	ClinGen Ensembl
TCGA novel	23	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343751832 rs1353856360	25	T>A		No	ClinGen gnomAD
rs999235861 CA343751828	25	T>I		No	ClinGen TOPMed gnomAD
CA32754397 rs999235861	25	T>N		No	ClinGen TOPMed gnomAD
CA1249937 rs139831401	26	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA343751800 rs1335290339	28	Q>*		No	ClinGen gnomAD
COSM424626 CA32754379 rs994018186	30	R>*	Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs201830798 CA1249934	30	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1249935 rs201830798 COSM3687805	30	R>Q	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA343751720 rs1427837069	33	S>L		No	ClinGen TOPMed
CA1249932 rs147657848	34	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs758553316 CA1249931	38	S>N		No	ClinGen ExAC TOPMed gnomAD
CA1249929 rs778918147	38	S>R		No	ClinGen ExAC TOPMed gnomAD
CA343751593 rs753688759	42	L>V		No	ClinGen ExAC TOPMed gnomAD
CA343751577 rs1362936641	43	T>I		No	ClinGen TOPMed gnomAD
CA1249926 rs373147233	45	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA1249924 rs750186632	46	R>*		No	ClinGen ExAC TOPMed gnomAD
rs750186632 CA343751555	46	R>G		No	ClinGen ExAC TOPMed gnomAD
CA343751551 rs767450186	46	R>P		No	ClinGen ExAC gnomAD
CA1249923 rs767450186	46	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs774194739 CA1249921	50	P>L		No	ClinGen ExAC TOPMed gnomAD
rs1363607351 CA343751498	50	P>S		No	ClinGen TOPMed gnomAD
rs1479323967 CA343751473	52	C>R		No	ClinGen TOPMed
rs1358009223 CA343751466	52	C>Y		No	ClinGen gnomAD
rs762589173 CA1249919	53	S>L		No	ClinGen ExAC TOPMed gnomAD
rs762589173 CA1249920	53	S>W		No	ClinGen ExAC TOPMed gnomAD
rs771407346 CA1249917	54	Q>H		No	ClinGen ExAC gnomAD
rs747479891 CA1249916	55	L>F		No	ClinGen ExAC TOPMed gnomAD
rs772451925 CA1249915	56	Q>P		No	ClinGen ExAC gnomAD
rs772451925 CA1249914	56	Q>R		No	ClinGen ExAC gnomAD
rs1370488914 CA343750524	57	E>D		No	ClinGen TOPMed
CA1249895 rs761125900	57	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1323092912 CA343750511	58	D>E		No	ClinGen TOPMed gnomAD
rs144027979 CA1249894	58	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs772398782 CA1249893	59	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1391937983 CA343750487	60	D>G		No	ClinGen gnomAD
rs1172538157 CA343750457	62	Q>*		No	ClinGen gnomAD
CA343750426 rs1466006233	63	K>N		No	ClinGen gnomAD
CA343750420 rs1422792514	64	V>F		No	ClinGen gnomAD
CA343750424 rs1422792514	64	V>I		No	ClinGen gnomAD
CA343750408 rs1268779099	65	A>S		No	ClinGen TOPMed gnomAD
CA1249892 rs748581087	67	L>F		No	ClinGen ExAC TOPMed gnomAD
CA343750347 rs1490985112	70	K>E		No	ClinGen gnomAD
rs774545206 CA1249891	74	L>S		No	ClinGen ExAC TOPMed gnomAD
rs369035559 CA1249890	75	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs7418622 CA32751637	76	S>N		No	ClinGen Ensembl
rs538592242 CA1249889	78	T>I		No	ClinGen 1000Genomes ExAC gnomAD
rs1203940804 CA343750227	78	T>S		No	ClinGen gnomAD
rs780132844 CA1249888	79	P>S		No	ClinGen ExAC TOPMed gnomAD
CA32751627 rs1021446812	80	L>V		No	ClinGen TOPMed gnomAD
TCGA novel	82	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745768571 CA1249886	85	Y>C		No	ClinGen ExAC gnomAD
CA343750133 rs1438873745	87	N>D		No	ClinGen gnomAD
rs199842348 CA1249884	87	N>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs759796518 CA1249881	93	R>G		No	ClinGen ExAC gnomAD
TCGA novel	93	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1249880 rs758033141	95	L>F		No	ClinGen ExAC gnomAD
CA343750077 rs1416115548	95	L>H		No	ClinGen gnomAD
rs1422081628 CA343750053	98	F>L		No	ClinGen TOPMed
CA1249877 rs759090025	99	I>V		No	ClinGen ExAC gnomAD
CA1249876 rs372282461	100	V>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs768071600 CA1249875	101	A>G		No	ClinGen ExAC gnomAD
CA32751564 rs1029680394	103	K>E		No	ClinGen Ensembl
CA343750017 rs1231532691	104	Q>P		No	ClinGen gnomAD
rs774711348 CA32751562	108	A>G		No	ClinGen ExAC gnomAD
rs774711348 CA1249873	108	A>V		No	ClinGen ExAC gnomAD
rs768923320 CA1249872	110	E>A		No	ClinGen ExAC gnomAD
CA1249870 rs138099730	111	V>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA1249871 rs763212615	111	V>M		No	ClinGen ExAC TOPMed gnomAD
CA1249869 rs557642625	116	N>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1249868 VAR_027081 rs12086855	117	I>F		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs781432131 CA1249867	118	K>R		No	ClinGen ExAC TOPMed gnomAD
CA1249866 rs770921269	120	I>N		No	ClinGen ExAC TOPMed gnomAD
rs1359644753	122	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA1249865 rs746971504	123	T>A		No	ClinGen ExAC TOPMed gnomAD
rs758180138 CA1249863	124	L>P		No	ClinGen ExAC gnomAD
CA343749872 rs1158802622	127	M>R		No	ClinGen TOPMed gnomAD
rs754113095 CA1249862	128	K>E		No	ClinGen ExAC TOPMed gnomAD
CA343749863 rs1268963763	128	K>R		No	ClinGen TOPMed
rs1405415343 CA343749848	130	T>I		No	ClinGen gnomAD
CA1249861 rs144722707	133	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA343749824 rs1183958847	134	P>A		No	ClinGen gnomAD
CA1249860 rs754472381	134	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs762268983 CA1249857	135	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA1249856 rs752054283	137	F>I		No	ClinGen ExAC gnomAD
TCGA novel	137	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM3934270 rs1007733437 CA32751486 COSM3934269	140	Q>R	oesophagus [Cosmic]	No	ClinGen cosmic curated TOPMed
rs1195069833 CA343748379	141	I>L		No	ClinGen gnomAD
CA343748343 rs1337364781	144	K>E		No	ClinGen gnomAD
rs528965924 CA1249838	146	Q>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1249836 rs758953713	149	S>P		No	ClinGen ExAC gnomAD
rs1300757505 CA343748246	150	E>D		No	ClinGen gnomAD
CA1249835 rs752933190	151	N>S		No	ClinGen ExAC gnomAD
CA343748236 rs752933190	151	N>T		No	ClinGen ExAC gnomAD
CA32748438 rs899167469	152	R>G		No	ClinGen Ensembl
TCGA novel	152	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343748206 rs1328582538	153	E>D		No	ClinGen gnomAD
rs1378040286 CA343748219	153	E>K		No	ClinGen gnomAD
rs1036470566 CA32748432	154	G>D		No	ClinGen Ensembl
CA343748132 rs1272127836	159	T>A		No	ClinGen TOPMed
CA1249832 rs200815000	162	F>V		No	ClinGen ExAC gnomAD
CA1249830 rs760737838	163	C>S		No	ClinGen ExAC gnomAD
CA1249829 rs773191929	164	C>S		No	ClinGen ExAC gnomAD
rs1363508108 CA343748060	165	V>I		No	ClinGen gnomAD
rs757321947 CA1249827	169	S>G		No	ClinGen ExAC TOPMed gnomAD
CA1249826 rs369995400	170	L>V		No	ClinGen ESP ExAC gnomAD
rs1205719296 CA343748020	171	L>M		No	ClinGen TOPMed
rs1277595643 CA343748003	173	T>S		No	ClinGen gnomAD
rs751694607 CA1249824	174	V>A		No	ClinGen ExAC TOPMed gnomAD
rs566411021 CA1249823	175	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA1249822 rs755636666	176	E>Q		No	ClinGen ExAC gnomAD
CA32748368 rs546596379	177	D>Y		No	ClinGen 1000Genomes
CA343747948 rs1237303999	182	P>S		No	ClinGen gnomAD
rs1414711835 CA343747938	183	L>F		No	ClinGen gnomAD
CA343747943 rs1314011403	183	L>V		No	ClinGen gnomAD
rs1310750273 CA343747914	186	A>T		No	ClinGen gnomAD
CA1249820 rs780754361	186	A>V		No	ClinGen ExAC TOPMed gnomAD
CA1249818 rs753266757	187	N>H		No	ClinGen ExAC TOPMed gnomAD
rs751817930 CA32748360	187	N>K		No	ClinGen TOPMed
rs765678249 CA1249817	189	A>P		No	ClinGen ExAC gnomAD
rs1157071135 CA343747868	190	E>K		No	ClinGen gnomAD
CA343747841 rs1468376180	192	N>D		No	ClinGen gnomAD
TCGA novel	195	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1249816 rs755437217	195	I>V		No	ClinGen ExAC gnomAD
rs964424861 CA32748330	196	I>T		No	ClinGen TOPMed
rs1188500701 CA343747795	196	I>V		No	ClinGen gnomAD
TCGA novel	197	G>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343747735 rs1381545173	199	W>C		No	ClinGen gnomAD
CA32748326 rs979008831	202	K>E		No	ClinGen TOPMed
CA343747703 rs1474834605	202	K>R		No	ClinGen gnomAD
rs1459501941 CA343747683	203	T>I		No	ClinGen TOPMed
TCGA novel	204	F>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1218122371 CA343747650	206	C>G		No	ClinGen gnomAD
CA1249814 rs766770133	206	C>Y		No	ClinGen ExAC TOPMed gnomAD
rs773099596 CA1249812	209	S>R		No	ClinGen ExAC gnomAD
CA1249811 rs767669166	210	P>S		No	ClinGen ExAC gnomAD
CA1249810 rs761609032	211	L>V		No	ClinGen ExAC TOPMed gnomAD
CA1249809 rs774310854	212	A>T		No	ClinGen ExAC TOPMed gnomAD
CA343747501 rs1354079523	213	I>M		No	ClinGen gnomAD
CA343747486 rs1280704912	214	N>S		No	ClinGen TOPMed gnomAD
rs1367037571 CA343747466	215	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA32748308 rs1025828219	219	S>A		No	ClinGen TOPMed
CA32748306 rs995220059	219	S>C		No	ClinGen TOPMed
rs967731883 CA343747372	220	W>*		No	ClinGen TOPMed
CA32748294 rs967731883	220	W>C		No	ClinGen TOPMed
CA343747339 rs1400640624	222	A>V		No	ClinGen gnomAD
rs1316412659 CA343747308	224	M>I		No	ClinGen gnomAD
CA1249808 rs766564911	224	M>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	227	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1165369201 CA343747185	230	M>I		No	ClinGen gnomAD
CA343747186 rs762795112	230	M>R		No	ClinGen ExAC gnomAD
CA1249807 rs762795112	230	M>T		No	ClinGen ExAC gnomAD
rs962493885 CA32748282	230	M>V		No	ClinGen TOPMed gnomAD
CA343747108 rs1485354608	234	V>M		No	ClinGen TOPMed
rs775277356 CA343747074	236	T>A		No	ClinGen ExAC gnomAD
rs775277356 CA1249806	236	T>S		No	ClinGen ExAC gnomAD
rs1415550770 CA343747062	237	T>A		No	ClinGen TOPMed gnomAD
TCGA novel	238	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs769260488 CA1249805	242	S>T		No	ClinGen ExAC gnomAD
rs375786847 CA1249804	243	V>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA343746924 rs41265234	245	C>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs956680000 CA32748240	245	C>R		No	ClinGen Ensembl
CA1249803 rs41265234	245	C>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA343746918 rs1190504676	245	C>W		No	ClinGen gnomAD
CA343746877 rs1383923406	248	Q>R		No	ClinGen TOPMed
rs1253283189 CA343746861	249	S>I		No	ClinGen TOPMed gnomAD
CA343746857 rs1253283189	249	S>T		No	ClinGen TOPMed gnomAD
rs1213435781 CA343746826	252	I>V		No	ClinGen gnomAD
rs1363033655 CA343746796	253	S>F		No	ClinGen gnomAD
rs143910289 CA343746780	254	F>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	255	A>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA343746778 rs779634048	255	A>S		No	ClinGen ExAC TOPMed gnomAD
CA1249800 rs779634048 COSM899784	255	A>T	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs755386136 CA1249799	255	A>V		No	ClinGen ExAC gnomAD
CA1249798 rs139873333	256	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1438788037 CA343746739	261	A>T		No	ClinGen gnomAD
TCGA novel	262	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs147875545 CA1249796	263	A>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs1439825393 CA343746719	264	L>V		No	ClinGen TOPMed gnomAD
CA343746710 rs1189955949	265	W>L		No	ClinGen gnomAD
rs1172646763 CA343746705	266	D>N		No	ClinGen gnomAD
rs767473743 CA1249794	267	S>G		No	ClinGen ExAC gnomAD
TCGA novel	268	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA32748202 rs376503908	273	G>E		No	ClinGen Ensembl
TCGA novel	273	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	274	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1249793 rs762017774	274	E>G		No	ClinGen ExAC gnomAD
CA1249791 rs763961090	281	D>N		No	ClinGen ExAC TOPMed gnomAD
CA343746576 rs1437759520	284	M>I		No	ClinGen gnomAD
rs139044055 CA1249789	285	D>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs769650444 CA1249788	286	C>Y		No	ClinGen ExAC gnomAD
rs191005165 CA1249787	289	S>L		No	ClinGen 1000Genomes ExAC gnomAD
CA1249785 rs770345706	290	H>Q		No	ClinGen ExAC gnomAD
rs1368440798 CA343746532	291	F>V		No	ClinGen gnomAD
CA343746479 rs1299654969	298	H>D		No	ClinGen gnomAD
rs1571956646 CA343746464	300	S>P		No	ClinGen Ensembl
rs150724604 CA1249783	302	T>S		No	ClinGen 1000Genomes ExAC gnomAD
rs1326798259 CA343746430	305	V>A		No	ClinGen TOPMed gnomAD
CA32748153 rs1036782482	306	R>C		No	ClinGen TOPMed gnomAD
CA1249781 rs41265232	306	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs41265232 CA1249782	306	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs750604400 CA1249778	310	S>A		No	ClinGen ExAC gnomAD
CA1249777 rs199858256	310	S>C		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	311	V>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1249776 rs141850049	313	S>L		No	ClinGen ESP ExAC
CA1249774 rs751570406	316	T>A		No	ClinGen ExAC
CA1249773 rs144597243	319	K>N		No	ClinGen ESP ExAC gnomAD
rs1474070062 CA343746344	320	I>L		No	ClinGen TOPMed
rs776106025 CA1249756	323	L>R		No	ClinGen ExAC gnomAD
CA343816217 rs1184050135	323	L>V		No	ClinGen gnomAD
CA343816191 rs1257515336	326	K>N		No	ClinGen gnomAD
rs1374481875 CA343816174	329	I>F		No	ClinGen TOPMed
CA343816172 rs1185860910	329	I>T		No	ClinGen TOPMed gnomAD
rs770040755 CA1249755	333	A>P		No	ClinGen ExAC TOPMed gnomAD
CA527394702 rs1316054826	340	I>N		No	ClinGen gnomAD
rs142489691 CA1249753	340	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1235140064 CA343816072	344	E>G		No	ClinGen TOPMed
CA527394697 rs1234976963	345	E>A		No	ClinGen gnomAD

No associated diseases with Q8N0S6

No regional properties for Q8N0S6

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q8N0S6

Functions

		Description
EC Number
Subcellular Localization	Nucleus Chromosome, centromere	Localizes exclusively in the centromeres The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

3 GO annotations of cellular component

Name	Definition
chromosome, centromeric region	The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.

No GO annotations of molecular function

Name	Definition
No GO annotations for molecular function

No GO annotations of biological process

Name	Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q1T7C0	CENPL	Centromere protein L	Gallus gallus (Chicken)	PR
Q28HN9	cenpl	Centromere protein L	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR

10	20	30	40	50	60
MDSYSAPEST	PSASSRPEDY	FIGATPLQKR	LESVRKQSSF	ILTPPRRKIP	QCSQLQEDVD
70	80	90	100	110	120
PQKVAFLLHK	QWTLYSLTPL	YKFSYSNLKE	YSRLLNAFIV	AEKQKGLAVE	VGEDFNIKVI
130	140	150	160	170	180
FSTLLGMKGT	QRDPEAFLVQ	IVSKSQLPSE	NREGKVLWTG	WFCCVFGDSL	LETVSEDFTC
190	200	210	220	230	240
LPLFLANGAE	SNTAIIGTWF	QKTFDCYFSP	LAINAFNLSW	MAAMWTACKM	DHYVATTEFL
250	260	270	280	290	300
WSVPCSPQSL	DISFAIHPED	AKALWDSVHK	TPGEVTQEEV	DLFMDCLYSH	FHRHFKIHLS
310	320	330	340
ATRLVRVSTS	VASAHTDGKI	KILCHKYLIG	VLAYLTELAI	FQIE