Q28HN9

PR
Gene name
cenpl (TTpA009f13.1)
Protein name
Centromere protein L
Names
CENP-L
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:733519
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-160 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q28HN9

Entry ID Method Resolution Chain Position Source
AF-Q28HN9-F1 Predicted AlphaFoldDB

No variants for Q28HN9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q28HN9

No associated diseases with Q28HN9

No regional properties for Q28HN9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q28HN9

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Chromosome, centromere
  • Localizes exclusively in the centromeres
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chromosome, centromeric region The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q1T7C0 CENPL Centromere protein L Gallus gallus (Chicken) PR
Q8N0S6 CENPL Centromere protein L Homo sapiens (Human) PR
10 20 30 40 50 60
MQSPTNGVST PKDFSSARRS IQFQNTGFPQ IGLASARRHT PFHHAPSKRR IPQTSPLSET
70 80 90 100 110 120
VDPLKIALLL SKQWTLYSVT PMHKFSYTNL KEYARLLSAH ICAEKQKGLA VEVGTELNVK
130 140 150 160 170 180
ATFSPLPGLK GREQDPGSIL IQVLAKPQFS AAGAQDRIVW SGCFCCTFAD EDTLDLLTSE
190 200 210 220 230 240
TLLCLPLFLV NGAEALTAMV GTWFQKAFDC SFSNLPISSR DLAWMAAMWT GYEAHEHITA
250 260 270 280 290 300
TEFIFSVPIE PHMDISYAIH PEDIKALWSN IHKGQDEVLA EEVDLLFQCL YTHFFRHFKI
310 320 330 340
HLSATHLVKV STSVASAHCD GKVKFLSKEY LLQVLGYLTE LAINNIQY