Q8LBB2
Gene name |
KING1 (CBSCBS1, At3g48530, T8P19.40) |
Protein name |
SNF1-related protein kinase regulatory subunit gamma-1 |
Names |
AKIN subunit gamma-1, AKING1, AKINgamma1, CBS domain-containing protein CBSCBS1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G48530 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8LBB2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8LBB2-F1 | Predicted | AlphaFoldDB |
18 variants for Q8LBB2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH14402075 | 35 | L>P | No | 1000Genomes | |
| tmp_3_17988163_G_A | 75 | D>N | No | 1000Genomes | |
| tmp_3_17988179_A_T | 80 | E>V | No | 1000Genomes | |
| tmp_3_17988513_T_G | 152 | L>R | No | 1000Genomes | |
| tmp_3_17988858_A_T | 236 | H>L | No | 1000Genomes | |
| tmp_3_17988933_C_T | 261 | P>L | No | 1000Genomes | |
| ENSVATH12640218 | 263 | M>T | No | 1000Genomes | |
| ENSVATH06271926 | 275 | E>K | No | 1000Genomes | |
| tmp_3_17989128_A_C | 300 | E>A | No | 1000Genomes | |
| ENSVATH02470628 | 346 | T>A | No | 1000Genomes | |
| tmp_3_17989408_A_C | 364 | K>T | No | 1000Genomes | |
| tmp_3_17989419_T_A | 368 | L>M | No | 1000Genomes | |
| ENSVATH06271927 | 372 | A>T | No | 1000Genomes | |
| tmp_3_17989461_G_A | 382 | D>N | No | 1000Genomes | |
| ENSVATH00408589 | 383 | D>E | No | 1000Genomes | |
| tmp_3_17989471_G_A | 385 | G>D | No | 1000Genomes | |
| ENSVATH06271928 | 390 | L>I | No | 1000Genomes | |
| tmp_3_17989565_G_A | 416 | M>I | No | 1000Genomes |
No associated diseases with Q8LBB2
4 regional properties for Q8LBB2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | CBS domain | 63 - 131 | IPR000644-1 |
| domain | CBS domain | 190 - 239 | IPR000644-2 |
| domain | CBS domain | 262 - 324 | IPR000644-3 |
| domain | CBS domain | 350 - 408 | IPR000644-4 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein kinase regulator activity | Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
| fatty acid biosynthetic process | The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. |
| nitrate assimilation | The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P38314 | SDS24 | Protein SDS24 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P53172 | SDS23 | Protein SDS23 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q9UGJ0 | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (Human) | PR |
| Q91WG5 | Prkag2 | 5'-AMP-activated protein kinase subunit gamma-2 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATVPEIKIM | RSESLGHRSD | VSSPEAKLGM | RVEDLWDEQK | PQLSPNEKLN | ACFESIPVSA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FPLSSDSQDI | EIRSDTSLAE | AVQTLSKFKV | LSAPVVDVDA | PEDASWIDRY | IGIVEFPGIV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VWLLHQLEPP | SPRSPAVAAS | NGFSHDFTTD | VLDNGDSAVT | SGNFFEVLTS | SELYKNTKVR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DISGTFRWAP | FLALQKENSF | LTMLLLLSKY | KMKSIPVVDL | GVAKIENIIT | QSGVIHMLAE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CAGLLWFEDW | GIKTLSEVGL | PIMSKDHIIK | IYEDEPVLQA | FKLMRRKRIG | GIPVIERNSE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KPVGNISLRD | VQFLLTAPEI | YHDYRSITTK | NFLVSVREHL | EKCGDTSAPI | MSGVIACTKN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HTLKELILML | DAEKIHRIYV | VDDFGNLEGL | ITLRDIIARL | VHEPSGYFGD | FFDGVMPLPE |
| NYRV |