P38314

PR
Gene name
SDS24 (YBR214W, YBR1501)
Protein name
Protein SDS24
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YBR214W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-112 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P38314

Entry ID Method Resolution Chain Position Source
AF-P38314-F1 Predicted AlphaFoldDB

6 variants for P38314

Variant ID(s) Position Change Description Diseaes Association Provenance
s02-651499 30 M>I No SGRP
s02-651611 68 C>S No SGRP
s02-651629 74 P>A No SGRP
s02-652016 203 P>S No SGRP
s02-652368 320 G>D No SGRP
s02-652977 523 G>D No SGRP

No associated diseases with P38314

4 regional properties for P38314

Type Name Position InterPro Accession
domain CBS domain 118 - 167 IPR000644-1
domain CBS domain 198 - 256 IPR000644-2
domain CBS domain 283 - 342 IPR000644-3
domain CBS domain 368 - 415 IPR000644-4

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleotide-activated protein kinase complex A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
AMP binding Binding to AMP, adenosine monophosphate.
protein kinase binding Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
protein kinase regulator activity Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.
protein serine/threonine phosphatase inhibitor activity Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.

6 GO annotations of biological process

Name Definition
cellular response to glucose starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
protein phosphorylation The process of introducing a phosphate group on to a protein.
regulation of catalytic activity Any process that modulates the activity of an enzyme.
regulation of mitotic metaphase/anaphase transition Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
septum digestion after cytokinesis The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P53172 SDS23 Protein SDS23 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q8LBB2 KING1 SNF1-related protein kinase regulatory subunit gamma-1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MASTSNTFPP SQSNSSNNLP TSRHASIVEM LSTPPLLPHV QVNDTDDKEQ PEESTPPTAT
70 80 90 100 110 120
AAAPGPGCAA TPAPLRDEKP QFKLSAVPMT QTPSQCLSCV HAQKWQHIPL SQLIEQNKLI
130 140 150 160 170 180
FVPGSISVEE AFNTLIKYHL NSIPVESFPG DMNCFTFDYN DLNSYLLLVL NKITVSNKQL
190 200 210 220 230 240
TADCQNGKPV PVGEMVKLTP KNPFYKLPEN ESLSTVMGIL GSGVHRVAIT NEEMTKVKGI
250 260 270 280 290 300
LSQRRLIKYL WDNARSFTSL EPLLNSSLQD LHIGVLNIQS KPTSRQSRVI SIQGEEPLIM
310 320 330 340 350 360
GLYKMHVERI SSIAVIDKQG NLLGNISVTD VKHVTRTSQY PLLHKTCRHF ISVILNSRGL
370 380 390 400 410 420
ETGKDSFPIF HVYPSSSLAR TLAKLVATKS HRLWIVQPPE SSTSASSTNL TAANTAANAV
430 440 450 460 470 480
SATAQSSANG ATPMSKSSSS TSLNSHSPLM TAMEDPPSPR SSAIAIPPPS PASSTNTPNL
490 500 510 520
FEKEYRTGKL IGVVSLTDII NLLARKQTGN KEVDPQSARR QRGSIAM