AiPD: Autoinhibited Protein Database

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

516-604 (Predicted disordered autoinhibitory region) PR

516-604 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8K114-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3389292174	12	L>I	No	EVA
rs3389261381	24	I>N	No	EVA
rs3389332658	41	L>S	No	EVA
rs3389333746	62	A>T	No	EVA
rs3405175555	67	E>D	No	EVA
rs3405107003	67	E>Q	No	EVA
rs3405194838	67	E>V	No	EVA
rs3389326921	159	K>N	No	EVA
rs3412878035	226	I>T	No	EVA
rs3389261423	238	S>T	No	EVA
rs3389333785	271	T>I	No	EVA
rs3389338035	280	E>V	No	EVA
rs3389301474	311	C>R	No	EVA
rs3389353423	318	S>F	No	EVA
rs3389309824	326	F>L	No	EVA
rs3389340420	327	Y>F	No	EVA
rs3389332636	350	N>Y	No	EVA
rs3389343110	358	P>T	No	EVA
rs3389336237	390	P>S	No	EVA
rs3389261414	412	W>L	No	EVA
rs49558279	420	I>V	No	EVA
rs3389292171	440	A>D	No	EVA
rs3389261371	464	V>E	No	EVA
rs3389353459	491	D>N	No	EVA
rs233135710	525	S>T	No	EVA
rs3389332651	539	T>A	No	EVA
rs3389336174	544	L>V	No	EVA
rs45803182	575	I>V	No	EVA
rs3389332634	642	T>I	No	EVA

Type	Name	Position	InterPro Accession
domain	Metallo-beta-lactamase	85 - 238	IPR001279
domain	Beta-Casp domain	305 - 433	IPR022712

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
integrator complex	A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
No GO annotations for molecular function

Name	Definition
snRNA 3'-end processing	Any process involved in forming the mature 3' end of an snRNA molecule.
snRNA processing	Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q2KJA6	INTS9	Integrator complex subunit 9	Bos taurus (Bovine)	PR
Q5ZKK2	INTS9	Integrator complex subunit 9	Gallus gallus (Chicken)	PR
Q9NV88	INTS9	Integrator complex subunit 9	Homo sapiens (Human)	PR