Q5ZKK2

PR
Gene name
INTS9 (RCJMB04_10e20)
Protein name
Integrator complex subunit 9
Names
Int9
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:422023
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

114-187 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5ZKK2

Entry ID Method Resolution Chain Position Source
AF-Q5ZKK2-F1 Predicted AlphaFoldDB

No variants for Q5ZKK2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ZKK2

No associated diseases with Q5ZKK2

5 regional properties for Q5ZKK2

Type Name Position InterPro Accession
domain Helicase, C-terminal 353 - 518 IPR001650
domain Mitochondrial degradasome RNA helicase subunit, C-terminal domain 625 - 670 IPR022192
domain Suv3, C-terminal domain 1 558 - 598 IPR041082
domain Suv3, N-terminal 62 - 179 IPR041453
domain Suv3, DEXQ-box helicase domain 200 - 345 IPR044774

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integrator complex A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
snRNA 3'-end processing Any process involved in forming the mature 3' end of an snRNA molecule.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2KJA6 INTS9 Integrator complex subunit 9 Bos taurus (Bovine) PR
Q9NV88 INTS9 Integrator complex subunit 9 Homo sapiens (Human) PR
Q8K114 Ints9 Integrator complex subunit 9 Mus musculus (Mouse) PR
10 20 30 40 50 60
MKLYCLSGHP TLPCNVLKFK STTIMLDCGL DMTSTLNFLP LPLVQSPRLS KLPGLVLKDG
70 80 90 100 110 120
STFLDKELKE CSGHVFVDSV PEFCLPETEL LDLSTVDVIL ISNYHCMMAL PYITEYTGFT
130 140 150 160 170 180
GTVYATEPTV QIGRLLMEEL VNSIERVPKA QSASTWKNKE VQRLLPAPLK DAVEVSMWRK
190 200 210 220 230 240
CYTMPEVNAA LSKIQLVGYS QKIELFGAVQ VTPLSSGYAL GSSNWIIQSH YEKVSYVSGS
250 260 270 280 290 300
SLLTTHPQPM DQASLKNSDV LILTGLTQIP TANPDGMVGE FCSNLAMTVR NGGNVLVPCY
310 320 330 340 350 360
PSGVIYDLLE CLYQYIDSAG LSNVPFYFIS PVANSSLEFS QIFAEWLCHN KQTKVYLPEP
370 380 390 400 410 420
PFPHAELIQT NKLKHYPSIH GDFSNDFKQP CVIFTGHPSL RFGDVVHFME LWGKSSLNTV
430 440 450 460 470 480
IFTEPDFSYL DALAPYQPLA MKCVYCPIDT RLNFIQVSKL LKEVQPLHVV CPEQYTQPPP
490 500 510 520 530 540
SQSHRTDLMI DCQPPPMSYR RAEVLTLPYK RRYEKIEIMP ELADSLVPLE IKPGISLATV
550 560 570 580 590 600
SAMLHTKDNK HVLQLPPKPP QPPTSKKRKR VSDDVPECKP LKPLLSGSIP VDQFVQTLEK
610 620 630 640 650
HGFSDVKVED TAKGHIVLLQ EAETLIQIEE DSTHIICDND EPLRVKLRDL VLKFLQKF