AiPD: Autoinhibited Protein Database

Q8IXB3

Gene name	TRARG1
Protein name	Trafficking regulator of GLUT4 1
Names	Dispanin subfamily B member 1, DSPB1, Interferon-induced transmembrane domain-containing protein D3, Protein located at seventeen-p-thirteen point three 1, Tumor suppressor candidate 5
Species	Homo sapiens (Human)
KEGG Pathway	hsa:286753
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-124 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

2-124 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q8IXB3

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8IXB3-F1	Predicted				AlphaFoldDB

207 variants for Q8IXB3

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA397520318 rs1344736629	2	A>G		No	ClinGen gnomAD
rs760146336 CA8265834	2	A>T		No	ClinGen ExAC gnomAD
rs75616699 CA8265835 VAR_029589	3	H>Y		No	ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD
CA8265836 rs753774828	4	P>L		No	ClinGen ExAC gnomAD
rs1196162829 CA397520335	5	V>A		No	ClinGen gnomAD
CA8265838 rs765124946	7	S>C		No	ClinGen ExAC TOPMed gnomAD
CA397520346 rs1173826888	7	S>P		No	ClinGen TOPMed
rs758716428 CA8265840	8	E>K		No	ClinGen ExAC gnomAD
rs1598185991 CA397520359	9	F>V		No	ClinGen Ensembl
rs1429037358 CA397520368	10	P>L		No	ClinGen TOPMed
rs1168241505 CA397520385	13	Q>*		No	ClinGen gnomAD
CA8265842 rs751625945	13	Q>R		No	ClinGen ExAC gnomAD
rs1371809442 CA397520396	14	E>D		No	ClinGen gnomAD
rs1325612642 CA397520394	14	E>G		No	ClinGen gnomAD
CA8265843 rs755077393	14	E>K		No	ClinGen ExAC gnomAD
rs111587833 CA286744635	15	P>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA397520400 rs1184529604	15	P>L		No	ClinGen TOPMed
CA8265844 VAR_029590 rs111587833	15	P>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs770104149 CA8265846	16	G>A		No	ClinGen ExAC gnomAD
rs1355227640 CA397520415	18	A>D		No	ClinGen TOPMed gnomAD
CA286744646 rs111701043	18	A>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8265848 VAR_029591 rs111701043	18	A>T		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA397520418 rs1468529132	19	A>E		No	ClinGen gnomAD
CA8265851 rs199751182	19	A>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA397520416 rs199751182	19	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs6502774 CA286744693	20	F>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8265852 rs6502774 VAR_029592	20	F>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA397520424 rs6502774	20	F>Y		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs776561613 CA8265853	22	D>H		No	ClinGen ExAC TOPMed gnomAD
CA8265854 rs761869292	23	L>P		No	ClinGen ExAC gnomAD
rs1193647945 CA397520440	23	L>V		No	ClinGen gnomAD
CA8265855 rs765075771	24	P>L		No	ClinGen ExAC
rs762879334 CA8265857	26	M>I		No	ClinGen ExAC TOPMed gnomAD
rs1395370433 CA397520477	28	I>R		No	ClinGen gnomAD
CA397520476 rs1395370433 COSM242139	28	I>T	prostate [Cosmic]	No	ClinGen cosmic curated gnomAD
rs1191422406 CA397520473	28	I>V		No	ClinGen TOPMed gnomAD
rs1373155421 CA397520483	29	L>P		No	ClinGen TOPMed
rs190456061 CA8265859	30	L>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA397520488 rs1368006465	30	L>P	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs930288091 CA286744748	31	T>I		No	ClinGen TOPMed gnomAD
CA286744754 rs984350544	32	K>E		No	ClinGen gnomAD
CA8265860 VAR_029593 rs75025906	34	E>D		No	ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD
rs767526514 CA8265861	35	N>K		No	ClinGen ExAC gnomAD
CA8265864 rs560160029	37	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs749652638 CA8265865	38	D>E		No	ClinGen ExAC TOPMed gnomAD
CA8265866 rs757679975	39	K>E		No	ClinGen ExAC TOPMed gnomAD
CA397520558 rs1205639597	41	L>V		No	ClinGen gnomAD
CA8265868 rs746643952	44	S>C		No	ClinGen ExAC gnomAD
rs768168367 CA8265869	45	K>N		No	ClinGen ExAC gnomAD
rs1418883199 CA397520593	47	L>I		No	ClinGen gnomAD
rs527632397 CA8265870	48	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs201434030 CA286744820	49	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen 1000Genomes NCI-TCGA
rs895363969 CA286744834	50	P>L		No	ClinGen TOPMed
rs762826527 CA8265874	50	P>S		No	ClinGen ExAC TOPMed gnomAD
CA8265875 rs766094067	51	L>R		No	ClinGen ExAC gnomAD
CA8265876 rs371689207	52	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA397520621 rs1218495154	52	D>G		No	ClinGen TOPMed
rs1400577991 CA397520617	52	D>N		No	ClinGen gnomAD
rs201625477 CA8265877	54	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs201625477 CA397520629	54	E>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA286744860 rs552062038	56	N>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA397520652 rs6502776	57	S>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
VAR_029594 CA8265880 rs6502776	57	S>G		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA397520651 rs6502776	57	S>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1332986088 CA397520660	58	Q>*		No	ClinGen TOPMed
rs375213755 CA286744880	59	G>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA8265881 rs375213755	59	G>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs866986320 CA286744881	61	P>A		No	ClinGen Ensembl
CA8265882 rs754353569	62	F>S		No	ClinGen ExAC gnomAD
CA8265883 rs757573314	63	K>E		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	63	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs757573314 CA397520687	63	K>Q		No	ClinGen ExAC TOPMed gnomAD
CA397520708 rs1212786758	66	S>P		No	ClinGen gnomAD
CA397520710 rs1464982179	66	S>Y		No	ClinGen TOPMed
CA8265886 rs754563276	67	E>D		No	ClinGen ExAC gnomAD
rs751171532 CA8265885	67	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA397520723 rs1166818204	68	G>A		No	ClinGen TOPMed
CA397520719 rs1410332590	68	G>R		No	ClinGen gnomAD
CA8265887 rs780938203	71	E>G		No	ClinGen ExAC TOPMed gnomAD
CA397520748 rs1567927245	72	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA8265889 rs369899312	74	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA8265890 rs777788387	74	L>P		No	ClinGen ExAC TOPMed gnomAD
rs777788387 CA397520757	74	L>Q		No	ClinGen ExAC TOPMed gnomAD
CA286744909 rs369899312	74	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs770710409 CA397520767	76	R>L		No	ClinGen ExAC TOPMed gnomAD
CA8265892 rs770710409	76	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs749271661 CA8265891	76	R>W		No	ClinGen ExAC gnomAD
rs773995458 CA397520774	78	P>S		No	ClinGen ExAC gnomAD
CA8265893 rs773995458	78	P>T		No	ClinGen ExAC gnomAD
CA8265895 rs772183424	79	S>F		No	ClinGen ExAC gnomAD
TCGA novel	79	S>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs200966114 CA397520786	80	R>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs200966114 CA8265898	80	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8265897 rs760691629	80	R>W		No	ClinGen ExAC TOPMed gnomAD
CA397520787 rs1275487896	81	A>T		No	ClinGen TOPMed
CA8265899 rs754300458	81	A>V		No	ClinGen ExAC gnomAD
rs762244907 CA8265901 CA8265900	84	R>S		No	ClinGen ExAC gnomAD
rs568148069 CA8265902	85	R>W		No	ClinGen 1000Genomes ExAC gnomAD
CA8265904 rs372635148	86	A>E		No	ClinGen ExAC TOPMed gnomAD
CA8265903 COSM1231432 rs372635148	86	A>V	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1190697258 CA397520822	87	S>P		No	ClinGen gnomAD
rs1189419630 CA397520842	90	A>T		No	ClinGen gnomAD
CA397520850 rs1323633453	91	T>I		No	ClinGen Ensembl
rs375426779 CA8265911	93	S>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA286745095 rs1034846432	95	A>G		No	ClinGen gnomAD
CA397520880 rs372563106	96	Q>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA8265912 rs372563106	96	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA397520889 rs1355938101	97	D>E		No	ClinGen gnomAD
CA397520892 rs1442413012	98	Q>*		No	ClinGen gnomAD
CA8265914 rs760915398	100	A>D		No	ClinGen ExAC gnomAD
CA397520907 rs1368149210	100	A>T		No	ClinGen TOPMed gnomAD
rs760915398 CA397520911	100	A>V		No	ClinGen ExAC gnomAD
CA397520918 rs1364243886	102	R>G		No	ClinGen gnomAD
CA8265916 rs776666793	103	D>N		No	ClinGen ExAC gnomAD
CA8265917 rs761992799	104	Y>D		No	ClinGen ExAC gnomAD
CA397520935 rs1598186285	104	Y>S		No	ClinGen Ensembl
TCGA novel	105	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	105	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
COSM3712255 rs72816260 CA8265918	106	I>T	upper_aerodigestive_tract [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA286745157 COSM352012 rs971805745	108	A>D	lung [Cosmic]	No	ClinGen cosmic curated Ensembl
CA397520965 rs1567927294	109	V>A		No	ClinGen Ensembl
CA8265920 rs763167536 COSM352013	109	V>I	lung Variant assessed as Somatic; 4.668e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA8265923 rs752350080 COSM1470905	110	V>I	prostate [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs752350080 CA8265924	110	V>L		No	ClinGen ExAC TOPMed gnomAD
CA8265926 rs753286797	111	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1192261469 CA397520975	111	A>V		No	ClinGen TOPMed
COSM109157 CA286745205 rs140849117	115	P>S	skin [Cosmic]	No	ClinGen cosmic curated Ensembl
rs56071414 CA8265931	116	V>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs56071414 CA8265929	116	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs56071414 CA8265930	116	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8265933 rs746851996	117	W>*		No	ClinGen ExAC gnomAD
CA8265934 rs768832176	118	P>L		No	ClinGen ExAC gnomAD
rs1387847729 CA397521017	118	P>T		No	ClinGen gnomAD
CA397521032 rs1382500698	120	N>S		No	ClinGen TOPMed gnomAD
CA8265936 rs928019418	122	I>N		No	ClinGen TOPMed
TCGA novel	122	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1362382645 CA397521051	123	P>S		No	ClinGen gnomAD
rs762000687	124	L>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs1337166747 CA397521073	126	I>M		No	ClinGen gnomAD
rs748162909 CA8265938	126	I>V		No	ClinGen ExAC gnomAD
rs1214418422 CA397521087	129	M>L		No	ClinGen gnomAD
CA397521091 rs1567927346	129	M>T		No	ClinGen Ensembl
rs1052112216 CA286762310	131	R>*		No	ClinGen TOPMed gnomAD
rs200319809 CA8265969	131	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs200319809 COSM264500 CA8265970	131	R>Q	lung Variant assessed as Somatic; 0.0 impact. large_intestine [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA397521656 TCGA novel rs1344942677	132	S>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen gnomAD
rs1189106758 CA397521660	133	S>N		No	ClinGen TOPMed
rs373545515 CA8265971	133	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA397521670 rs1177740267	134	M>I		No	ClinGen TOPMed
CA397521668 rs1467971930	134	M>T		No	ClinGen TOPMed gnomAD
CA397521683 rs1282982313	136	Q>*		No	ClinGen gnomAD
CA8265972 rs751510149	136	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs781071180 CA8265974	137	G>A		No	ClinGen ExAC gnomAD
CA397521689 rs754701438	137	G>C		No	ClinGen ExAC TOPMed gnomAD
rs754701438 CA8265973	137	G>R		No	ClinGen ExAC TOPMed gnomAD
rs781071180 CA397521690	137	G>V		No	ClinGen ExAC gnomAD
CA8265975 rs369302621	138	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs777926793 CA397521700	139	V>L		No	ClinGen ExAC TOPMed gnomAD
rs777926793 CA8265977 COSM3378076	139	V>M	pancreas [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs916272871 CA286762417	141	G>S		No	ClinGen TOPMed gnomAD
CA397521714 rs1396714659	141	G>V		No	ClinGen gnomAD
rs779499580 CA8265980	142	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1394633037 CA397521721	142	A>V		No	ClinGen gnomAD
rs1411811214 CA397521722	143	R>G		No	ClinGen TOPMed gnomAD
rs746411798 CA8265982	143	R>P		No	ClinGen ExAC TOPMed gnomAD
CA8265981 rs746411798	143	R>Q		No	ClinGen ExAC TOPMed gnomAD
COSM975557 rs1411811214 CA397521723	143	R>W	endometrium [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA286762461 rs1035830727	144	R>S		No	ClinGen Ensembl
CA8265983 rs775897419	145	L>M		No	ClinGen ExAC gnomAD
rs779102520 COSM3378077 CA8265985	147	R>C	pancreas [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs370410748 COSM975558 CA8265986	147	R>H	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA8265987 rs762389709	149	A>S		No	ClinGen ExAC TOPMed gnomAD
CA8265989 rs751457450	150	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs374210765 CA8265988	150	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs1467625236 CA397521765	152	L>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA8265990 rs759447889	153	S>G		No	ClinGen ExAC gnomAD
rs1454623153 CA397521789	155	T>I		No	ClinGen gnomAD
COSM472313 rs1454623153 CA397521788	155	T>S	kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA8265992 rs752534868	156	L>P		No	ClinGen ExAC gnomAD
rs1235262932 CA397521791	156	L>V		No	ClinGen gnomAD
CA8265995 rs370923967	157	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA8265994 rs370923967	157	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA397521818 rs1459969392	160	G>S		No	ClinGen gnomAD
rs757375759 CA8265996	161	I>T		No	ClinGen ExAC gnomAD
rs1327951523 CA397521826	161	I>V		No	ClinGen gnomAD
CA8265998 rs200766728	162	V>I		No	ClinGen ExAC TOPMed gnomAD
CA286762559 rs201414985	163	I>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8266001 rs201414985	163	I>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8266000 rs201414985	163	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs772782807 CA8266003	164	I>T		No	ClinGen ExAC TOPMed gnomAD
CA8266005 rs770378061 CA397521851	165	M>I		No	ClinGen ExAC TOPMed gnomAD
CA286762594 rs187534319	165	M>T		No	ClinGen 1000Genomes TOPMed gnomAD
rs762625401 CA8266004	165	M>V		No	ClinGen ExAC TOPMed gnomAD
rs1434416986 CA397521855	166	V>E		No	ClinGen TOPMed gnomAD
rs376944339 CA8266006	167	A>T		No	ClinGen ESP ExAC gnomAD
rs372589098 CA8266008 COSM172212	168	V>M	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1022986829 CA286762607	169	T>I		No	ClinGen TOPMed gnomAD
CA397521871 rs1022986829	169	T>S		No	ClinGen TOPMed gnomAD
rs1378961733 CA397521874	170	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs760454130 CA8266010	172	F>L		No	ClinGen ExAC TOPMed gnomAD
rs760454130 CA397521888	172	F>V		No	ClinGen ExAC TOPMed gnomAD
CA8266012 rs533341843	173	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA286762659 rs533341843	173	T>R		No	ClinGen 1000Genomes ExAC gnomAD
CA8266013 rs757527314	174	V>I		No	ClinGen ExAC TOPMed gnomAD
rs771564599 CA8266047	175	Q>R		No	ClinGen ExAC
rs746565517 CA8266049	176	K>E		No	ClinGen ExAC gnomAD
rs768705249 CA8266050 COSM975561	176	K>N	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD

No associated diseases with Q8IXB3

4 regional properties for Q8IXB3

Type	Name	Position	InterPro Accession
repeat	WD40 repeat	283 - 320	IPR001680-1
repeat	WD40 repeat	377 - 455	IPR001680-2
repeat	WD40 repeat	499 - 538	IPR001680-3
repeat	WD40 repeat	541 - 578	IPR001680-4

Functions

		Description
EC Number
Subcellular Localization	Cell membrane ; Single-pass membrane protein Endomembrane system ; Single-pass membrane protein Cytoplasm, perinuclear region	Shifts from low-density microsome vesicles to the cell membrane upon insulin stimulation
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

6 GO annotations of cellular component

Name	Definition
cytoplasmic vesicle membrane	The lipid bilayer surrounding a cytoplasmic vesicle.
endomembrane system	A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
perinuclear region of cytoplasm	Cytoplasm situated near, or occurring around, the nucleus.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name	Definition
No GO annotations for molecular function

5 GO annotations of biological process

Name	Definition
cellular response to insulin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
endosome to plasma membrane protein transport	The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.
glucose import in response to insulin stimulus	The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus.
protein localization to plasma membrane	A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
vesicle fusion to plasma membrane	Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.

3 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
B4DJY2	TMEM233	Transmembrane protein 233	Homo sapiens (Human)	PR
Q8C838	Trarg1	Trafficking regulator of GLUT4 1	Mus musculus (Mouse)	PR
Q2MHH0	Trarg1	Trafficking regulator of GLUT4 1	Rattus norvegicus (Rat)	PR

10	20	30	40	50	60
MAHPVQSEFP	SAQEPGSAAF	LDLPEMEILL	TKAENKDDKT	LNLSKTLSGP	LDLEQNSQGL
70	80	90	100	110	120
PFKAISEGHL	EAPLPRSPSR	ASSRRASSIA	TTSYAQDQEA	PRDYLILAVV	ACFCPVWPLN
130	140	150	160	170
LIPLIISIMS	RSSMQQGNVD	GARRLGRLAR	LLSITLIIMG	IVIIMVAVTV	NFTVQKK