Q2MHH0
Gene name |
Trarg1 |
Protein name |
Trafficking regulator of GLUT4 1 |
Names |
Brain endothelial cell-derived protein 1, BEC-1, Dispanin subfamily B member 1, DSPB1, Tumor suppressor candidate 5 homolog |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:360576 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2MHH0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2MHH0-F1 | Predicted | AlphaFoldDB |
No variants for Q2MHH0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2MHH0 | |||||
No associated diseases with Q2MHH0
No regional properties for Q2MHH0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q2MHH0 | |||
Functions
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic vesicle membrane | The lipid bilayer surrounding a cytoplasmic vesicle. |
| endomembrane system | A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to insulin stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. |
| endosome to plasma membrane protein transport | The directed movement of proteins from the endosome to the plasma membrane in transport vesicles. |
| establishment of localization in cell | Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. |
| glucose import in response to insulin stimulus | The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus. |
| protein localization to plasma membrane | A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. |
| vesicle fusion to plasma membrane | Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MANPVQPQLQ | DPGSTSPLDL | PEMEKLLTKV | ENKDDQALNL | SKSLSGALDL | EQNGHSLPFK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VISEGHRQPS | LSGSPSRASS | RRASSVVTTS | YAQDQEAPKD | YLVLAIASCF | CPVWPLNLIP |
| 130 | 140 | 150 | 160 | 170 | |
| LIFSIMSRSS | VQQGDLDGAR | RLGRLARLLS | ITFIILGIVI | IIVAVTVNFT | VPK |