Q8IPK4

PR
Gene name
CG31915
Protein name
Glycosyltransferase 25 family member
Names
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG31915
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

524-612 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8IPK4

Entry ID Method Resolution Chain Position Source
AF-Q8IPK4-F1 Predicted AlphaFoldDB

No variants for Q8IPK4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8IPK4

No associated diseases with Q8IPK4

2 regional properties for Q8IPK4

Type Name Position InterPro Accession
domain Fatty acyl-coenzyme A reductase, NAD-binding domain 130 - 400 IPR013120
domain Fatty acyl-CoA reductase, C-terminal 472 - 562 IPR033640

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum lumen
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
endoplasmic reticulum lumen The volume enclosed by the membranes of the endoplasmic reticulum.

1 GO annotations of molecular function

Name Definition
procollagen galactosyltransferase activity Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine.

1 GO annotations of biological process

Name Definition
positive regulation of collagen fibril organization Any process that activates or increases the frequency, rate or extent of collagen fibril organization.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A7MB73 CERCAM Probable inactive glycosyltransferase 25 family member 3 Bos taurus (Bovine) PR
Q5T4B2 CERCAM Inactive glycosyltransferase 25 family member 3 Homo sapiens (Human) PR
O60568 PLOD3 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 Homo sapiens (Human) PR
A3KGW5 Cercam Inactive glycosyltransferase 25 family member 3 Mus musculus (Mouse) PR
Q20679 let-268 Multifunctional procollagen lysine hydroxylase and glycosyltransferase Caenorhabditis elegans PR
10 20 30 40 50 60
MNKQVIFGLL LACILVCISG QDEEDYQESP TVLIALLVRN KAHILPMFLS YLEQQDYPKE
70 80 90 100 110 120
RIAIWLRCDH SNDDSIELLR QWLDNSGDLY HSVSYEFKPE EQSFVNGTSP YEWPASRFKH
130 140 150 160 170 180
LIALKEEAFQ YGRDIWADYV FFLDADVLLT SKDSLKVLTR LQLPIVAPML ISESLYSNFW
190 200 210 220 230 240
CGMTEDYYYR RTDEYKEIYH VKKQGSFPVP MVHTAVLVNM NHRAVRNLTF DRNKLVELQK
250 260 270 280 290 300
SRQQEPLYDG PADDIIVFAI SANSSGIPLH ICNDITFGYI LQPLEPGDTL DHDVQQLVNL
310 320 330 340 350 360
KSIMVNELGA VPPLLDYYKH LEKKPEKSKL SLDRIFMINL KRRPERREKM ERLFDEIGIE
370 380 390 400 410 420
AEHFPAVDGK ELSTERLLEM GVRFLPGYED PYHHRAMTMG EIGCFLSHYN IWVMMVRKQL
430 440 450 460 470 480
KEVLILEDDI RFEPYFRQNA VRILNQARNA AQYDLIYFGR KRLKEESEPA VENADNLVHA
490 500 510 520 530 540
GYSYWTLGYV ISLQGALKLL AAKPLDKLIP VDEFLPLMFD RHPNKTWTEA FPKRNLVAFS
550 560 570 580 590 600
ASPLLLYPIY YTGESGYISD TEDSQQISVE TSEEGEARLK SDREQVFDHE QEFKLNPELK
610
LGESLSKSHQ EL