A7MB73
PR
Gene name |
CERCAM (CEECAM1, GLT25D3) |
Protein name |
Probable inactive glycosyltransferase 25 family member 3 |
Names |
Cerebral endothelial cell adhesion molecule |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:516122 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7MB73
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7MB73-F1 | Predicted | AlphaFoldDB |
294 variants for A7MB73
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs461446013 | 85 | A>G | No | EVA | |
| rs448595761 | 87 | V>G | No | EVA | |
| rs523193771 | 90 | N>D | No | EVA | |
| rs437295612 | 95 | V>G | No | EVA | |
| rs450850202 | 98 | P>A | No | EVA | |
| rs464550249 | 101 | E>G | No | EVA | |
| rs432248822 | 102 | P>A | No | EVA | |
| rs797905327 | 121 | F>L | No | EVA | |
| rs459828919 | 131 | T>P | No | EVA | |
| rs516280611 | 139 | D>A | No | EVA | |
| rs442138241 | 142 | L>P | No | EVA | |
| rs466509355 | 143 | F>L | No | EVA | |
| rs435151849 | 146 | T>S | No | EVA | |
| rs476093334 | 147 | D>H | No | EVA | |
| rs438312388 | 148 | N>T | No | EVA | |
| rs451805336 | 149 | I>F | No | EVA | |
| rs472029750 | 149 | I>N | No | EVA | |
| rs472029750 | 149 | I>S | No | EVA | |
| rs440652891 | 150 | L>P | No | EVA | |
| rs462992530 | 152 | N>K | No | EVA | |
| rs442760707 | 152 | N>S | No | EVA | |
| rs482152733 | 153 | N>T | No | EVA | |
| rs444365713 | 155 | T>A | No | EVA | |
| rs477764756 | 160 | I>V | No | EVA | |
| rs466472724 | 169 | P>A | No | EVA | |
| rs469051291 | 172 | D>E | No | EVA | |
| rs448762703 | 172 | D>G | No | EVA | |
| rs480386321 | 172 | D>N | No | EVA | |
| rs438274944 | 173 | S>A | No | EVA | |
| rs451984419 | 173 | S>C | No | EVA | |
| rs438274944 | 173 | S>T | No | EVA | |
| rs465669404 | 175 | T>P | No | EVA | |
| rs454336757 | 176 | Y>* | No | EVA | |
| rs434137545 | 176 | Y>S | No | EVA | |
| rs442937449 | 179 | N>T | No | EVA | |
| rs474279335 | 179 | N>Y | No | EVA | |
| rs456462612 | 180 | F>C | No | EVA | |
| rs476680290 | 181 | W>G | No | EVA | |
| rs438791370 | 183 | G>A | No | EVA | |
| rs457854249 | 185 | T>P | No | EVA | |
| rs477924614 | 187 | Q>P | No | EVA | |
| rs135616522 | 190 | Y>S | No | EVA | |
| rs456574529 | 194 | A>P | No | EVA | |
| rs438728130 | 195 | D>G | No | EVA | |
| rs476733070 | 195 | D>H | No | EVA | |
| rs471490542 | 196 | Y>* | No | EVA | |
| rs452426586 | 196 | Y>N | No | EVA | |
| rs473985322 | 197 | F>L | No | EVA | |
| rs460167261 | 197 | F>S | No | EVA | |
| rs440313580 | 197 | F>V | No | EVA | |
| rs458556440 | 202 | R>L | No | EVA | |
| rs444832562 | 202 | R>S | No | EVA | |
| rs479301342 | 203 | Q>E | No | EVA | |
| rs468053885 | 204 | R>G | No | EVA | |
| rs436542921 | 207 | C>Y | No | EVA | |
| rs450217039 | 209 | R>S | No | EVA | |
| rs432482031 | 216 | T>A | No | EVA | |
| rs432482031 | 216 | T>P | No | EVA | |
| rs452389899 | 218 | L>M | No | EVA | |
| rs472445095 | 220 | S>A | No | EVA | |
| rs434758112 | 221 | L>M | No | EVA | |
| rs453953513 | 221 | L>R | No | EVA | |
| rs442575683 | 223 | A>G | No | EVA | |
| rs474131386 | 223 | A>P | No | EVA | |
| rs432637287 | 227 | G>A | No | EVA | |
| rs462758702 | 228 | Q>P | No | EVA | |
| rs438564589 | 230 | A>G | No | EVA | |
| rs476324684 | 230 | A>P | No | EVA | |
| rs461627052 | 235 | H>P | No | EVA | |
| rs461627052 | 235 | H>R | No | EVA | |
| rs432445225 | 243 | D>E | No | EVA | |
| rs470422398 | 243 | D>H | No | EVA | |
| rs446065033 | 245 | I>T | No | EVA | |
| rs466106767 | 247 | V>L | No | EVA | |
| rs434719436 | 248 | F>L | No | EVA | |
| rs454861221 | 249 | A>V | No | EVA | |
| rs457891035 | 257 | V>F | No | EVA | |
| rs471364737 | 257 | V>G | No | EVA | |
| rs440217121 | 258 | A>P | No | EVA | |
| rs480411307 | 259 | V>A | No | EVA | |
| rs460218616 | 259 | V>I | No | EVA | |
| rs448848793 | 262 | C>* | No | EVA | |
| rs462595132 | 263 | N>T | No | EVA | |
| rs483280081 | 265 | Q>P | No | EVA | |
| rs445518263 | 266 | R>G | No | EVA | |
| rs434142172 | 268 | G>W | No | EVA | |
| rs447801761 | 279 | G>A | No | EVA | |
| rs467875736 | 284 | R>G | No | EVA | |
| rs476452146 | 287 | F>L | No | EVA | |
| rs432355654 | 289 | H>P | No | EVA | |
| rs451469200 | 292 | L>P | No | EVA | |
| rs451469200 | 292 | L>R | No | EVA | |
| rs471688839 | 293 | E>A | No | EVA | |
| rs440173247 | 294 | A>E | No | EVA | |
| rs440173247 | 294 | A>V | No | EVA | |
| rs473927379 | 295 | L>R | No | EVA | |
| rs460333638 | 295 | L>V | No | EVA | |
| rs454435648 | 296 | V>A | No | EVA | |
| rs442534299 | 296 | V>L | No | EVA | |
| rs436764631 | 307 | V>G | No | EVA | |
| rs474372126 | 307 | V>M | No | EVA | |
| rs457449735 | 308 | S>A | No | EVA | |
| rs471121604 | 314 | P>A | No | EVA | |
| rs439772729 | 314 | P>L | No | EVA | |
| rs459975106 | 318 | G>V | No | EVA | |
| rs473486688 | 319 | F>I | No | EVA | |
| rs473486688 | 319 | F>L | No | EVA | |
| rs473486688 | 319 | F>V | No | EVA | |
| rs442146779 | 321 | E>D | No | EVA | |
| rs432787213 | 322 | V>G | No | EVA | |
| rs467262676 | 323 | F>V | No | EVA | |
| rs435749663 | 324 | V>A | No | EVA | |
| rs435749663 | 324 | V>G | No | EVA | |
| rs475896382 | 325 | I>F | No | EVA | |
| rs475896382 | 325 | I>L | No | EVA | |
| rs444588591 | 325 | I>T | No | EVA | |
| rs451833418 | 326 | S>R | No | EVA | |
| rs471765633 | 326 | S>T | No | EVA | |
| rs459615324 | 327 | L>R | No | EVA | |
| rs440417621 | 327 | L>V | No | EVA | |
| rs441741698 | 328 | A>P | No | EVA | |
| rs476769425 | 332 | D>H | No | EVA | |
| rs476769425 | 332 | D>Y | No | EVA | |
| rs450455902 | 340 | S>L | No | EVA | |
| rs446421288 | 343 | E>D | No | EVA | |
| rs477811503 | 343 | E>V | No | EVA | |
| rs435923576 | 344 | M>I | No | EVA | |
| rs467274405 | 344 | M>L | No | EVA | |
| rs449490839 | 345 | E>D | No | EVA | |
| rs469536735 | 346 | I>S | No | EVA | |
| rs438213952 | 349 | R>P | No | EVA | |
| rs451796663 | 350 | V>E | No | EVA | |
| rs451796663 | 350 | V>G | No | EVA | |
| rs471895617 | 351 | V>G | No | EVA | |
| rs433957851 | 352 | D>E | No | EVA | |
| rs454069657 | 353 | A>T | No | EVA | |
| rs461885987 | 354 | V>A | No | EVA | |
| rs461885987 | 354 | V>G | No | EVA | |
| rs441906522 | 354 | V>M | No | EVA | |
| rs444219625 | 355 | D>E | No | EVA | |
| rs452107050 | 358 | M>V | No | EVA | |
| rs472871569 | 359 | L>V | No | EVA | |
| rs461481576 | 361 | S>R | No | EVA | |
| rs441507058 | 361 | S>T | No | EVA | |
| rs474981509 | 362 | S>N | No | EVA | |
| rs477568306 | 367 | L>I | No | EVA | |
| rs445994232 | 369 | V>A | No | EVA | |
| rs445994232 | 369 | V>G | No | EVA | |
| rs459792412 | 370 | D>N | No | EVA | |
| rs479869189 | 371 | L>V | No | EVA | |
| rs467688766 | 375 | Y>S | No | EVA | |
| rs481177799 | 377 | D>A | No | EVA | |
| rs469843369 | 379 | Y>C | No | EVA | |
| rs449937049 | 379 | Y>D | No | EVA | |
| rs3423332392 | 383 | T>M | No | EVA | |
| rs432104007 | 383 | T>P | No | EVA | |
| rs452001392 | 384 | L>M | No | EVA | |
| rs434370723 | 386 | K>R | No | EVA | |
| rs455040860 | 389 | V>G | No | EVA | |
| rs443773601 | 390 | G>A | No | EVA | |
| rs475142916 | 390 | G>R | No | EVA | |
| rs457588186 | 391 | C>G | No | EVA | |
| rs471065381 | 392 | F>S | No | EVA | |
| rs379653526 | 393 | L>P | No | EVA | |
| rs439644588 | 395 | H>P | No | EVA | |
| rs459789632 | 395 | H>Q | No | EVA | |
| rs479777960 | 397 | S>F | No | EVA | |
| rs518168991 | 405 | R>Q | No | EVA | |
| rs525500462 | 429 | Q>R | No | EVA | |
| rs455632536 | 449 | K>R | No | EVA | |
| rs876416041 | 451 | V>G | No | EVA | |
| rs475561264 | 452 | N>I | No | EVA | |
| rs475561264 | 452 | N>T | No | EVA | |
| rs444242716 | 455 | E>D | No | EVA | |
| rs451259640 | 461 | G>R | No | EVA | |
| rs876356973 | 462 | L>R | No | EVA | |
| rs440027929 | 463 | P>A | No | EVA | |
| rs443095534 | 464 | H>L | No | EVA | |
| rs473800175 | 464 | H>N | No | EVA | |
| rs443095534 | 464 | H>P | No | EVA | |
| rs445458338 | 466 | V>G | No | EVA | |
| rs483238590 | 466 | V>L | No | EVA | |
| rs478962804 | 467 | A>E | No | EVA | |
| rs478962804 | 467 | A>G | No | EVA | |
| rs458963348 | 467 | A>S | No | EVA | |
| rs478962804 | 467 | A>V | No | EVA | |
| rs447590366 | 469 | G>C | No | EVA | |
| rs436357413 | 470 | Y>S | No | EVA | |
| rs469319384 | 471 | S>F | No | EVA | |
| rs449058273 | 471 | S>P | No | EVA | |
| rs437764268 | 472 | Y>F | No | EVA | |
| rs451527711 | 473 | W>G | No | EVA | |
| rs451527711 | 473 | W>R | No | EVA | |
| rs471480914 | 474 | T>P | No | EVA | |
| rs473761506 | 476 | A>G | No | EVA | |
| rs453827153 | 476 | A>S | No | EVA | |
| rs442420888 | 477 | Y>H | No | EVA | |
| rs463197229 | 477 | Y>S | No | EVA | |
| rs476970108 | 478 | V>A | No | EVA | |
| rs438983272 | 481 | L>R | No | EVA | |
| rs461303648 | 483 | G>A | No | EVA | |
| rs447651594 | 483 | G>C | No | EVA | |
| rs469250444 | 484 | A>D | No | EVA | |
| rs469250444 | 484 | A>G | No | EVA | |
| rs450101676 | 484 | A>P | No | EVA | |
| rs437931737 | 485 | R>P | No | EVA | |
| rs433782630 | 486 | K>N | No | EVA | |
| rs465115598 | 486 | K>Q | No | EVA | |
| rs453790222 | 487 | L>R | No | EVA | |
| rs435962950 | 488 | L>P | No | EVA | |
| rs456162170 | 489 | A>G | No | EVA | |
| rs451133026 | 490 | S>A | No | EVA | |
| rs451133026 | 490 | S>P | No | EVA | |
| rs451133026 | 490 | S>T | No | EVA | |
| rs439047688 | 491 | Q>P | No | EVA | |
| rs439047688 | 491 | Q>R | No | EVA | |
| rs452695611 | 492 | P>A | No | EVA | |
| rs441384087 | 493 | L>P | No | EVA | |
| rs443588278 | 498 | P>A | No | EVA | |
| rs463725327 | 499 | V>L | No | EVA | |
| rs465278989 | 500 | D>E | No | EVA | |
| rs445098644 | 500 | D>G | No | EVA | |
| rs477449193 | 500 | D>Y | No | EVA | |
| rs447509941 | 502 | F>L | No | EVA | |
| rs478788299 | 502 | F>V | No | EVA | |
| rs467467705 | 504 | P>A | No | EVA | |
| rs436134018 | 505 | I>F | No | EVA | |
| rs436134018 | 505 | I>L | No | EVA | |
| rs469756368 | 506 | M>I | No | EVA | |
| rs456179254 | 506 | M>L | No | EVA | |
| rs456179254 | 506 | M>V | No | EVA | |
| rs431985559 | 510 | H>P | No | EVA | |
| rs452656998 | 510 | H>Q | No | EVA | |
| rs457418521 | 513 | E>Q | No | EVA | |
| rs471099391 | 513 | E>V | No | EVA | |
| rs439626368 | 514 | Q>E | No | EVA | |
| rs473405816 | 515 | Y>D | No | EVA | |
| rs481227925 | 520 | W>C | No | EVA | |
| rs461229388 | 520 | W>L | No | EVA | |
| rs461229388 | 520 | W>S | No | EVA | |
| rs449838274 | 521 | P>T | No | EVA | |
| rs477191657 | 522 | R>G | No | EVA | |
| rs445714986 | 522 | R>P | No | EVA | |
| rs434368734 | 527 | F>S | No | EVA | |
| rs468882889 | 529 | A>S | No | EVA | |
| rs437367036 | 531 | P>H | No | EVA | |
| rs457510048 | 532 | L>M | No | EVA | |
| rs133914873 | 535 | A>S | No | EVA | |
| rs471094453 | 537 | T>N | No | EVA | |
| rs433218367 | 538 | H>D | No | EVA | |
| rs433218367 | 538 | H>N | No | EVA | |
| rs453435881 | 539 | Y>H | No | EVA | |
| rs473368707 | 542 | D>G | No | EVA | |
| rs461237016 | 545 | W>G | No | EVA | |
| rs477010771 | 551 | T>K | No | EVA | |
| rs445678027 | 552 | S>C | No | EVA | |
| rs479195563 | 556 | D>A | No | EVA | |
| rs479195563 | 556 | D>G | No | EVA | |
| rs448012965 | 557 | D>E | No | EVA | |
| rs437524515 | 558 | D>A | No | EVA | |
| rs451193505 | 558 | D>E | No | EVA | |
| rs437524515 | 558 | D>G | No | EVA | |
| rs468896282 | 558 | D>H | No | EVA | |
| rs464679395 | 559 | S>G | No | EVA | |
| rs433382878 | 559 | S>N | No | EVA | |
| rs453399889 | 559 | S>R | No | EVA | |
| rs464679395 | 559 | S>R | No | EVA | |
| rs435559235 | 564 | S>R | No | EVA | |
| rs455702999 | 565 | W>G | No | EVA | |
| rs474918604 | 566 | T>P | No | EVA | |
| rs443449862 | 566 | T>S | No | EVA | |
| rs439397559 | 569 | Y>S | No | EVA | |
| rs479359034 | 570 | K>Q | No | EVA | |
| rs461668888 | 571 | T>N | No | EVA | |
| rs441592478 | 571 | T>P | No | EVA | |
| rs481874683 | 572 | L>R | No | EVA | |
| rs451067460 | 573 | R>G | No | EVA | |
| rs464880515 | 573 | R>P | No | EVA | |
| rs446973005 | 580 | A>P | No | EVA | |
| rs446973005 | 580 | A>T | No | EVA | |
| rs455820780 | 581 | G>D | No | EVA | |
| rs455820780 | 581 | G>V | No | EVA | |
| rs438005063 | 582 | G>R | No | EVA | |
| rs470730167 | 583 | S>C | No | EVA | |
| rs439356889 | 583 | S>N | No | EVA | |
| rs470730167 | 583 | S>R | No | EVA | |
| rs473016423 | 584 | G>A | No | EVA | |
| rs453026711 | 584 | G>W | No | EVA | |
| rs441647127 | 585 | H>L | No | EVA | |
| rs461880451 | 585 | H>Q | No | EVA | |
| rs481843820 | 588 | R>H | No | EVA | |
| rs444054761 | 590 | H>P | No | EVA | |
| rs458409566 | 593 | D>E | No | EVA | |
| rs478551374 | 594 | E>V | No | EVA |
No associated diseases with A7MB73
1 regional properties for A7MB73
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Rhodanese-like domain | 158 - 266 | IPR001763 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum lumen | The volume enclosed by the membranes of the endoplasmic reticulum. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| identical protein binding | Binding to an identical protein or proteins. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cell adhesion | The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8IPK4 | CG31915 | Glycosyltransferase 25 family member | Drosophila melanogaster (Fruit fly) | PR |
| Q5T4B2 | CERCAM | Inactive glycosyltransferase 25 family member 3 | Homo sapiens (Human) | PR |
| O60568 | PLOD3 | Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 | Homo sapiens (Human) | PR |
| A3KGW5 | Cercam | Inactive glycosyltransferase 25 family member 3 | Mus musculus (Mouse) | PR |
| Q20679 | let-268 | Multifunctional procollagen lysine hydroxylase and glycosyltransferase | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRAAPAAPLL | QLLLLLGPRP | EAAGVAEPPL | PTVVLAILAR | NAEHSLPHYL | GALERLDYPR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ARLALWCATD | HNVDNTTAML | REWLAAVGDN | YAAVVWRPEG | EPRSYPDEEG | PKHWTKERHQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FLMELKQEAL | TFARDWGADY | ILFADTDNIL | TNNQTLRLLI | EPGLPVVAPM | LDSQTYYSNF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WCGITPQGYY | RRTADYFPTK | NRQRRGCFRV | PMVHSTFLVS | LRAEGTGQLA | FYPPHPNYTW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PFDDIIVFAY | ACQAAGVAVH | VCNEQRYGYL | NVPVKSHQGL | EDERVNFIHL | ILEALVDGPP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MWASAHVSRP | PKRPSKMGFD | EVFVISLARR | PDRRERMLTS | LWEMEISGRV | VDAVDGRMLN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SSVMRTLGVD | LLPGYQDPYS | GRTLTKGEVG | CFLSHYSIWE | EVVTRGLAQV | VVFEDDVRFE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SNFKGRLEQL | MEEVEAEKLP | WDLIYLGRKQ | VNPEEEAVVE | GLPHLVAAGY | SYWTLAYVLS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LAGARKLLAS | QPLRRMLPVD | EFLPIMFDQH | PNEQYKAHFW | PRDLQAFSAR | PLLAAPTHYA |
| 550 | 560 | 570 | 580 | 590 | |
| GDSEWLSDTE | TSSPWDDDSG | RLISWTGSYK | TLRGPRLDLA | GGSGHSLRPH | PRDEL |