A3KGW5

PR
Gene name
Cercam (Ceecam1, Glt25d3)
Protein name
Inactive glycosyltransferase 25 family member 3
Names
Cerebral endothelial cell adhesion molecule
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:99151
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

509-592 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A3KGW5

Entry ID Method Resolution Chain Position Source
AF-A3KGW5-F1 Predicted AlphaFoldDB

30 variants for A3KGW5

Variant ID(s) Position Change Description Diseaes Association Provenance
rs222089347 2 H>L No EVA
rs242001424 15 Q>P No EVA
rs222464683 21 S>G No EVA
rs3388538288 39 A>S No EVA
rs3391430435 66 T>R No EVA
rs3388540185 67 D>V No EVA
rs27196611 92 V>I No EVA
rs3412829869 104 D>Y No EVA
rs3388537300 152 T>I No EVA
rs3388542713 162 P>Q No EVA
rs3388542770 180 G>W No EVA
rs3388539811 183 P>T No EVA
rs241500864 202 Q>L No EVA
rs3388542159 235 Y>* No EVA
rs265589040 236 S>T No EVA
rs230913866 256 M>V No EVA
rs216496586 311 L>P No EVA
rs3388537319 348 V>A No EVA
rs864265128 412 D>N No EVA
rs253717452 433 I>T No EVA
rs3388541573 454 V>L No EVA
rs3388541619 473 A>E No EVA
rs3388542172 477 S>G No EVA
rs3388541787 488 Q>H No EVA
rs3388539357 489 P>S No EVA
rs3388535291 509 N>I No EVA
rs3388537306 513 K>N No EVA
rs3388540152 541 E>K No EVA
rs27196593 562 Q>R No EVA
rs3388541751 566 Q>H No EVA

No associated diseases with A3KGW5

No regional properties for A3KGW5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A3KGW5

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum lumen
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
endoplasmic reticulum lumen The volume enclosed by the membranes of the endoplasmic reticulum.

1 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.

1 GO annotations of biological process

Name Definition
cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A7MB73 CERCAM Probable inactive glycosyltransferase 25 family member 3 Bos taurus (Bovine) PR
Q8IPK4 CG31915 Glycosyltransferase 25 family member Drosophila melanogaster (Fruit fly) PR
Q5T4B2 CERCAM Inactive glycosyltransferase 25 family member 3 Homo sapiens (Human) PR
O60568 PLOD3 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 Homo sapiens (Human) PR
Q20679 let-268 Multifunctional procollagen lysine hydroxylase and glycosyltransferase Caenorhabditis elegans PR
10 20 30 40 50 60
MHVARLLPLL LLLGQQLRAA SVTEPTLPTV VLAILARNAE HSLPHYLGAL ERLDYPRARL
70 80 90 100 110 120
ALWCATDHNM DNTTGMLREW LAAVGRDYAT VVWKPEEEAR SYPDEQGPKH WTKERHQFLM
130 140 150 160 170 180
ELRQEALAFA RDWGADYILF ADTDNILTNN QTLKLLIDRQ LPVVAPMLDS QTYYSNFWCG
190 200 210 220 230 240
ITPQGYYRRT AEYFPTKNRQ RQGCFRVPMV HSTFLLSLQT EETARLAFYP PHPNYSWPFD
250 260 270 280 290 300
DIIVFAYACQ AAGVSMHVCN DHRYGYMNVV VKPHQSLEEE KTNFIHLILE ALVDGPPMLA
310 320 330 340 350 360
SAHVSRPPKK LSKMGFDEVF VISLARRPQR RARMLSSLWE MEISAQVVDA VDGRTLNSSI
370 380 390 400 410 420
LKHLGVDLLP GYQDPYSGHT LTKGEVGCFL SHYSIWEEVV ARGLARVVVF EDDVRFKDNF
430 440 450 460 470 480
RRRLERLMED VLIQKLSWDL IYLGRKQVNP EEEVAVEGLP GLVVAGYSYW TLAYTLSLAG
490 500 510 520 530 540
ARKLLASQPL HRMLPVDEFL PVMFDRHPND QYKAYFWPRD LQAFSARPLL ASPTHYSGDA
550 560 570 580 590
EWLSDTETSS PWDDDSGRLI SQTGSQKALR GPHLHLTGSS GHSLHPHHRD EL