Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8GXH3

Entry ID Method Resolution Chain Position Source
AF-Q8GXH3-F1 Predicted AlphaFoldDB

51 variants for Q8GXH3

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06731559 2 S>N No 1000Genomes
ENSVATH12053408 5 S>P No 1000Genomes
ENSVATH06731562 9 A>G No 1000Genomes
ENSVATH06731563 11 I>V No 1000Genomes
tmp_4_10842165_G_C 13 C>S No 1000Genomes
ENSVATH06731564 15 P>S No 1000Genomes
tmp_4_10842191_T_G 22 S>A No 1000Genomes
tmp_4_10842194_G_A,C 23 E>K No 1000Genomes
tmp_4_10842194_G_A,C 23 E>Q No 1000Genomes
ENSVATH06731567 31 T>A No 1000Genomes
ENSVATH06731568 32 S>T No 1000Genomes
ENSVATH06731569 33 P>R No 1000Genomes
ENSVATH00525100 35 I>T No 1000Genomes
ENSVATH06731571 40 A>E No 1000Genomes
ENSVATH06731570 40 A>T No 1000Genomes
tmp_4_10842258_G_C 44 G>A No 1000Genomes
tmp_4_10842272_A_G 49 N>D No 1000Genomes
ENSVATH02889775 53 K>N No 1000Genomes
tmp_4_10842289_A_T 54 Q>H No 1000Genomes
tmp_4_10842291_G_A 55 R>K No 1000Genomes
ENSVATH06731572 63 P>S No 1000Genomes
tmp_4_10842345_A_T 73 E>V No 1000Genomes
ENSVATH02889776 75 A>T No 1000Genomes
ENSVATH06731576 83 N>S No 1000Genomes
ENSVATH00525101 87 R>Q No 1000Genomes
tmp_4_10842392_A_C 89 N>H No 1000Genomes
ENSVATH12053410 92 A>V No 1000Genomes
tmp_4_10842405_A_C 93 Y>S No 1000Genomes
tmp_4_10842416_G_A 97 V>I No 1000Genomes
ENSVATH06731578 117 S>C No 1000Genomes
ENSVATH12053412 130 R>S No 1000Genomes
ENSVATH02889777 132 A>S No 1000Genomes
ENSVATH00525103 156 V>I No 1000Genomes
tmp_4_10842735_T_G 172 S>A No 1000Genomes
tmp_4_10842759_G_T 180 A>S No 1000Genomes
ENSVATH12053466 200 S>A No 1000Genomes
tmp_4_10843024_C_A 221 P>T No 1000Genomes
ENSVATH06731599 226 Q>K No 1000Genomes
tmp_4_10843255_T_A 234 S>T No 1000Genomes
tmp_4_10843276_A_G 241 I>V No 1000Genomes
ENSVATH06731604 282 N>I No 1000Genomes
ENSVATH02889786 289 E>K No 1000Genomes
tmp_4_10843546_T_C 293 F>L No 1000Genomes
tmp_4_10843550_A_G 294 D>G No 1000Genomes
tmp_4_10843555_C_G 296 L>V No 1000Genomes
tmp_4_10843713_A_C 309 E>A No 1000Genomes
tmp_4_10843723_G_T 312 W>C No 1000Genomes
tmp_4_10843931_C_T 353 T>I No 1000Genomes
tmp_4_10843955_C_T 361 P>L No 1000Genomes
ENSVATH02889791 362 V>A No 1000Genomes
ENSVATH06731616 369 I>N No 1000Genomes

No associated diseases with Q8GXH3

No regional properties for Q8GXH3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8GXH3

Functions

Description
EC Number
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
chloroplast nucleoid The region of a chloroplast to which the DNA is confined.
mitochondrial nucleoid The region of a mitochondrion to which the DNA is confined.
nucleoid The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.

1 GO annotations of molecular function

Name Definition
single-stranded DNA binding Binding to single-stranded DNA.

2 GO annotations of biological process

Name Definition
mitochondrial DNA replication The process in which new strands of DNA are synthesized in the mitochondrion.
positive regulation of helicase activity Any process that activates or increases the activity of a helicase.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9FYJ2 OSB4 Protein OSB4, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9SX99 OSB1 Protein OSB1, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q8GWJ4 OSB3 Protein OSB3, chloroplastic/mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSLISKSLAR IECSPFFYPR ASEITTGKRI TSPQIRLYTA AAVGGKTGNG ERKQRAKAPA
70 80 90 100 110 120
KTPEAVTPVK PLEIASVTAT TENELPRPNE IAYESEVANW VNLIGFVDQP VQFEASSDGK
130 140 150 160 170 180
FWAGTVISQR SASDSSGFWI PIIFEGDLAK TAARYVSKDD QIHVSGKLFI DSPPPNMTYA
190 200 210 220 230 240
QANVQVLVQN LNFIQPMSPS PSPFMVMSSS EKEESGIKKQ PARAKQDIVI DEASDSWNHL
250 260 270 280 290 300
IENPKEWWDH RENKVNGLVK PRHPDFKSKD SSFSLWLNKA PNWVLPKLEG LEFDVLVPKA
310 320 330 340 350 360
RVVKQLKGEE SWKDLVQNPD KWWDNRIDKR NAKAPDFKHK ETGEALWLNE SPTWVLPKLP
370
PVKKKQESIV F